@article{2-s2.0-85213521584,

title = {Investigation of potential cytotoxicity of a water-soluble, red-fluorescent [70]fullerene nanomaterial in Drosophila melanogaster},

author = { M.M. Rost-Roszkowska and A.Z. Urbisz and K. Małota and G. Wilczek and M. Serda and M. Skonieczna},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85213521584&doi=10.1080%2f17435390.2024.2445250&partnerID=40&md5=16eb371b5b236a39631a4065a18f18ab},

doi = {10.1080/17435390.2024.2445250},

year  = {2025},

date = {2025-01-01},

journal = {Nanotoxicology},

publisher = {Taylor and Francis Ltd.},

abstract = {Fullerenes (C60; C70) as carbon nanomaterials can enter the environment through natural processes and anthropogenic activities, while synthetic fullerenes are commonly used in medicine in targeted therapies in association with antibodies, or anticancer and antimicrobial drugs. As the nanoparticles, they can pass through cell membranes and organelles and accumulate in the entire cytoplasm. The red-fluorescent, water-soluble [70]fullerene derivative C70-OMe-ser, which produces reactive oxygen species upon illumination with an appropriate wavelength, passed into the cytoplasm of the middle region in the Drosophila melanogaster digestive system. To determine whether [70]fullerene nanomaterials that produce fluorescence after entering the cell cytoplasm will hurt its homeostasis, it is necessary to investigate the activation of degenerative and possibly regenerative processes. In vivo, studies on the model species D. melanogaster may help to elucidate whether the water-soluble [70]fullerene derivative that produces fluorescence can still be considered among the most promising nanomaterials. The experiment involved feeding insects ad libitum with yeast paste supplemented with 40 µg of fullerenes/mL for 1 week and 1 month. Thus, adult females and males of D. melanogaster were divided into control (CWM; CWF; CMM; and CMF) and experimental groups (FWM; FWF; FMM; and FMF). The quantitative and qualitative analysis enabled the presentation of the effects of the water-soluble [70]fullerene derivatives on cell proliferation and degeneration. Our study presented that [70]fullerene derivative showed a cytoprotective effect and activated cell proliferation. Therefore, we could conclude that analyzed carbon nanomaterials seemed to be safe for the cells into which they have penetrated. © 2024 Informa UK Limited, trading as Taylor & Francis Group.},

note = {0},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-85178151628,

title = {Survival, growth and digestive functions after exposure to nanodiamonds - Transgenerational effects beyond contact time in house cricket strains},

author = { M. Augustyniak and A.K. Ajay and A. Kędziorski and M. Tarnawska and M.M. Rost-Roszkowska and B. Flasz and A. Babczyńska and B. Mazur and K. Rozpędek and R.S. Alian and M. Skowronek and E. Świerczek and Kl. Wiśniewska and P. Ziętara},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85178151628&doi=10.1016%2fj.chemosphere.2023.140809&partnerID=40&md5=8596e027ee47c37b61120de37d91f704},

doi = {10.1016/j.chemosphere.2023.140809},

year  = {2024},

date = {2024-01-01},

journal = {Chemosphere},

volume = {349},

publisher = {Elsevier Ltd},

abstract = {The long-term exposure effects of nanodiamonds (NDs), spanning an organism's entire lifespan and continuing for subsequent generation, remain understudied. Most research has focused on evaluating their biological impacts on cell lines and selected organisms, typically over short exposure durations lasting hours or days. The study aimed to assess growth, mortality, and digestive functions in wild (H) and long-lived (D) strains of Acheta domesticus (Insecta: Orthoptera) after two-generational exposure to NDs in concentrations of 0.2 or 2 mg kg−1 of food, followed by their elimination in the third generation. NDs induced subtle stimulating effect that depended on the strain and generation. In the first generation, more such responses occurred in the H than in the D strain. In the first generation of H strain insects, contact with NDs increased survival, stimulated the growth of young larvae, and the activity of most digestive enzymes in mature adults. The same doses and exposure time did not cause similar effects in the D strain. In the first generation of D strain insects, survival and growth were unaffected by NDs, whereas, in the second generation, significant stimulation of those parameters was visible. Selection towards longevity appears to support higher resistance of the insects to exposure to additional stressor, at least in the first generation. The cessation of ND exposure in the third generation caused potentially harmful changes, which included, e.g., decreased survival probability in H strain insects, slowed growth of both strains, as well as changes in heterochromatin density and distribution in nuclei of the gut cells in both strains. Such a reaction may suggest the involvement of epigenetic inheritance mechanisms, which may become inadequate after the stress factor is removed. © 2023 Elsevier Ltd},

note = {2},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-85184730898,

title = {Consumption of polypropylene caused some ultrastructural and physiological changes in some tissues of Galleria mellonella (Lepidoptera: Pyralidae) larvae},

author = { M.M. Rost-Roszkowska and P. Mermer and Ł. Chajec and A. Sosinka and G. Wilczek and S. Student and A.K. Wrońska and O. Karnówka},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85184730898&doi=10.1080%2f24750263.2024.2308529&partnerID=40&md5=bf8c4c030f37d08c900af092c647bfff},

doi = {10.1080/24750263.2024.2308529},

year  = {2024},

date = {2024-01-01},

journal = {European Zoological Journal},

volume = {91},

number = {1},

pages = {213-234},

publisher = {Taylor and Francis Ltd.},

abstract = {G. mellonella is a promising species for use in the biodegradation of plastics. It is easy to breed and has high resistance to diverse climatic conditions, which is particularly valuable when considering its potential application in the decomposition of plastics. Thus, it demonstrated the capacity for biodegradation of the most common types of plastics, such as polyethylene (PE) and polypropylene (PP). However, reports on whether consumed plastics or their decomposition products will adversely affect the structure and functioning of the internal organs are rather poor. The studies aimed to determine whether the consumption of PP by a greater wax moth larvae caused any ultrastructural changes in the organs of the animal’s body, evaluate the survival rate of the animals, and describe their reproduction. Thus, this study provided an understanding of histological and ultrastructural changes caused, or not caused, by the PP diet. We investigated three organs–midgut, silk gland, and fat body–under PP consumption by G. mellonella caterpillars (7th instar larvae). The level of reactive oxygen species (ROS) in selected organs, as well as the ability of larvae to survive and undergo metamorphosis were also examined. The animals were divided into four groups: G0-C, G0-S, G0-24, and G0-48. The research used transmission electron microscopy (TEM), confocal microscopy, and flow cytometry. Our study showed that a diet containing PP did not affect internal organs at the ultrastructural level. Cells in the analyzed organs–midgut, silk gland, and fat body–showed no degenerative changes. An increase in the intensity of autophagy and cell vacuolization was noted, but they probably act as a survival pathway. These observations suggest that the final larval stage of the greater wax moth can potentially be applied in PP biodegradation. © 2024 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.},

note = {1},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-85184696427,

title = {Toxic effects of nickel on tolerance and regeneration in the freshwater shrimp Neocaridina davidi},

author = { A. Ostróżka and Ł. Chajec and G. Wilczek and S. Student and K. Kocot and J. Homa and M.M. Rost-Roszkowska},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85184696427&doi=10.1080%2f24750263.2024.2310041&partnerID=40&md5=65d4437a7e8c700b222268bf3d805f30},

doi = {10.1080/24750263.2024.2310041},

year  = {2024},

date = {2024-01-01},

journal = {European Zoological Journal},

volume = {91},

number = {1},

pages = {180-205},

publisher = {Taylor and Francis Ltd.},

abstract = {Heavy metals cause environmental pollution and produce toxic effects on organisms. Nickel (Ni) is a common metallic pollutant of aquatic ecosystems and potentially can produce multifarious changes in the body of aquatic organisms. The average nickel content in rivers is about 0.7 μg/l. As a result, the homeostasis of the affected organism is disturbed, and processes that can counteract the changes are activated. To better understand the effects of Ni in the freshwater environment and its fauna, it is important to establish whether all changes caused in cells and tissues by Ni exposure are reversible when the animal returns to the non-polluted environment. Thus, the main aim of the study was to analyze changes that occur after Ni exposure and after it is returned to non-contaminated water at various levels of the animal’s body. The freshwater shrimp Neocaridina davidi (Crustacea) was selected as the subject of the study. As the organ for studies, we chose the midgut because it is a barrier against stressors that enter the organism. A concentration of 3.63 mg Ni/l was selected for the experiment, at which approximately 50% mortality of the population was observed after 14 days. The midgut was analyzed using light and transmission electron microscopy (TEM), confocal microscopy, and flow cytometry for qualitative and quantitative results. When the organisms were transferred to clean water, a prolong exposure resulted in a decrease in the values of the analyzed parameters (e.g. ROS; cell death; etc.) proportional to the purification time. The recovery time was insufficient to return to control values in most analyzed groups. Nevertheless, the occurrence of regenerative changes suggests that freshwater shrimps are relatively tolerant to nickel, when the exposure time is short and the recovery time is long. © 2024 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.},

note = {0},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-85180363492,

title = {Adaptation by death? Cell death-based tolerance to cadmium in 150-generation exposure of Spodoptera exiqua Hübner (Lepidoptera: Noctuidae)},

author = { A. Babczyńska and M.M. Rost-Roszkowska and A. Kafel and B. Łozowski and M. Augustyniak and M. Tarnawska},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85180363492&doi=10.1093%2fee%2fnvad077&partnerID=40&md5=65b08164a16d96d7682214b4d1536977},

doi = {10.1093/ee/nvad077},

issn = {0046225X},

year  = {2023},

date = {2023-01-01},

journal = {Environmental Entomology},

volume = {52},

number = {6},

pages = {1057-1070},

publisher = {Entomological Society of America},

abstract = {Mechanisms, including autophagy and apoptosis, which serve to regulate and ensure proper organism functions under optimal conditions, play additional defensive roles under environmental pressure.The aim of this study was to test the following hypotheses: (i) elevated autophagy and apoptosis intensity levels, as defensive processes in response to contact with cadmium, are maintained for a limited number of generations and (ii) the number of generations after which levels of cell death processes reach the reference level depends on selective pressure. Cell death processes were assessed by light and transmission electron microscopy, terminal deoxynucleotidyl transferase dUTP nick end labeling(TUNEL), and cytometric analyses. Model insects (Spodoptera exiqua; Hübner; 1808) were orally exposed to various concentrations of cadmium for 18 generations and compared with reference strains exposed to cadmium or not (control) for over 150 generations. Elevated programmed cell death intensity levels decreased after several generations, indicating tolerance of individuals to cadmium in the diet and verifying the first hypothesis; however, testing the second hypothesis indicated that the number of generations depended not only on pressure intensity, but also on cell death type, since levels of autophagy remained increased for a minimum of 12 generations. © The Author(s) 2023. Published by Oxford University Press on behalf of Entomological Society of America.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-85159275551,

title = {Influence of the modifiers in polyol method on magnetically induced hyperthermia and biocompatibility of ultrafine magnetite nanoparticles},

author = { A. Radoń and A. Włodarczyk and Ł. Sieroń and M.M. Rost-Roszkowska and Ł. Chajec and D. Łukowiec and A. Ciuraszkiewicz and P. Gȩbara and S. Wacławek and A. Kolano-Burian},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85159275551&doi=10.1038%2fs41598-023-34738-z&partnerID=40&md5=9fc8926f037eff98af4e0172e8e49528},

doi = {10.1038/s41598-023-34738-z},

issn = {20452322},

year  = {2023},

date = {2023-01-01},

journal = {Scientific Reports},

volume = {13},

number = {1},

publisher = {Nature Research},

abstract = {Magnetite nanoparticles (Fe3O4 NPs) are widely tested in various biomedical applications, including magnetically induced hyperthermia. In this study, the influence of the modifiers, i.e., urotropine, polyethylene glycol, and NH4HCO3, on the size, morphology, magnetically induced hyperthermia effect, and biocompatibility were tested for Fe3O4 NPs synthesized by polyol method. The nanoparticles were characterized by a spherical shape and similar size of around 10 nm. At the same time, their surface is functionalized by triethylene glycol or polyethylene glycol, depending on the modifiers. The Fe3O4 NPs synthesized in the presence of urotropine had the highest colloidal stability related to the high positive value of zeta potential (26.03 ± 0.55 mV) but were characterized by the lowest specific absorption rate (SAR) and intrinsic loss power (ILP). The highest potential in the hyperthermia applications have NPs synthesized using NH4HCO3, for which SAR and ILP were equal to 69.6 ± 5.2 W/g and 0.613 ± 0.051 nHm2/kg, respectively. Their application possibility was confirmed for a wide range of magnetic fields and by cytotoxicity tests. The absence of differences in toxicity to dermal fibroblasts between all studied NPs was confirmed. Additionally, no significant changes in the ultrastructure of fibroblast cells were observed apart from the gradual increase in the number of autophagous structures. © 2023, The Author(s).},

note = {5},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-85151449439,

title = {Uncovering nanotoxicity of a water-soluble and red-fluorescent [70]fullerene nanomaterial},

author = { D. Dreszer and G.M. Szewczyk and M. Szubka and A. Maroń and A.Z. Urbisz and K. Małota and J. Sznajder and M.M. Rost-Roszkowska and R. Musioł and M. Serda},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85151449439&doi=10.1016%2fj.scitotenv.2023.163052&partnerID=40&md5=d39a18e5d9df9484ec32cd0bbc2dafe3},

doi = {10.1016/j.scitotenv.2023.163052},

issn = {00489697},

year  = {2023},

date = {2023-01-01},

journal = {Science of the Total Environment},

volume = {879},

publisher = {Elsevier B.V.},

abstract = {Engineered fullerene materials have attracted the attention of researchers in the biomedical sciences, especially when their synthetic methodology is developed to endow them with significant levels of water-solubility and bioavailability. In this study, we synthesized and characterized a water-soluble and red-fluorescent [70]fullerene nanomaterial, which fluoresced at 693 nm with a quantum yield of 0.065 and a large Stokes shift (around 300 nm). The fullerene nanomaterial generated mainly singlet oxygen after illumination with blue LED light, while superoxide anion radical production was minimal. The transmission electron microscopy as well as fluorescent studies of Drosophila melanogaster revealed that prepared [70]fullerene nanoparticles had better bioavailability than pristine [70]fullerene nanoparticles. The designed nanomaterials were observed in the apical, perinuclear, and basal regions of digestive cells, as well as the basal lamina of the digestive system's epithelium, with no damage to cell organelles and no activation of degenerative processes and cell death. Our findings provide a new perspective for understanding the in vivo behavior of fullerene nanomaterials and their future application in bioimaging and light-activated nanotherapeutics. © 2023 Elsevier B.V.},

note = {2},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-85182557182,

title = {Inorganic nanoparticles and their applications in cosmetology [Nanoczastki nieorganiczne i ich zastosowanie w kosmetologii]},

author = { J. Szer and R.J. Balwierz and M.M. Rost-Roszkowska},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85182557182&doi=10.52336%2facm.2023.026&partnerID=40&md5=d38a277658aa0d8f87b0a2ca61008c1d},

doi = {10.52336/acm.2023.026},

issn = {27193241},

year  = {2023},

date = {2023-01-01},

journal = {Aesthetic Cosmetology and Medicine},

volume = {12},

number = {6},

pages = {229-235},

publisher = {INDYGO Zahir Media},

abstract = {Nanotechnology is a rapidly growing field of knowledge that finds application in many areas of everyday life - from cosmetology, medicine, the food industry, and environmental protection. This study aimed to present inorganic nanoparticles, as well as nanotechnology itself, with a limitation to its cosmetic applications and a focus on the safety aspect. Despite the vast potential and wide range of prospective uses, nanotechnology still raises numerous concerns regarding its application. One of the issues is the insufficient investigation of the enduring impacts of nanoparticles on the human body. However, nanoparticles are commonly found in the environment and their usage is expanding. © 2023 Kauno Technologijos Universitetas. All rights reserved.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-85165967465,

title = {How cadmium and copper change the sensitivity of the hemocytes of Steatoda grossa spider on immunostimulation: qualitative and quantitative analysis},

author = { G. Wilczek and M.M. Rost-Roszkowska and J. Homa and E. Szulińska and S. Student and Ł. Chajec and Kl. Wiśniewska and K. Surmiak-Stalmach},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85165967465&doi=10.1080%2f24750263.2023.2237989&partnerID=40&md5=d78134cfb2a4a0526661036b6548776b},

doi = {10.1080/24750263.2023.2237989},

issn = {24750263},

year  = {2023},

date = {2023-01-01},

journal = {European Zoological Journal},

volume = {90},

number = {2},

pages = {624-642},

publisher = {Taylor and Francis Ltd.},

abstract = {The purpose of this study was to evaluate the sensitivity of hemocytes of adult Steatoda grossa females to cadmium and copper administered orally for 4 weeks or 12 months, and to check the metabolic condition of these cells after immunostimulation with phorbol 12-myristate 13-acetate (PMA). The viability of hemocytes (flow cytometry and luminescence techniques), their ultrastructure (transmission electron microscopy), and the antioxidant activity of hemolymph (superoxide dismutase; catalase; total antioxidant capacity; TAC) were analyzed. The results showed that, compared to copper, cadmium caused severe necrotic changes in hemocytes and impaired oxygen burst reactions and antioxidant responses, regardless of the exposure time. Copper induced degenerative changes only during short-term exposure, but its long-term intoxication did not impair the metabolic processes of hemocytes. Administration of PMA to spiders that were chronically exposed to either of the metals caused an increase in TAC levels in the hemolymph. Although the concentration of ATP in hemocytes was reduced relative to the control, the ADP/ATP ratio did not change, precluding a strong depletion of cellular energy resources. The metabolic condition of hemocytes stabilized with prolonged metal exposure, indicating the activation of defense mechanisms under operating stressors. © 2023 University of Silesia. Published by Informa UK Limited, trading as Taylor & Francis Group.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-85144323876,

title = {Effect of gluten on the digestive tract and fat body of Telodeinopus aoutii (Diplopoda)},

author = { F. Błaszczyk and A. Sosinka and G. Wilczek and S. Student and M.M. Rost-Roszkowska},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85144323876&doi=10.1002%2fjmor.21546&partnerID=40&md5=e081a74179e2400fb67b1e829e62bcc9},

doi = {10.1002/jmor.21546},

issn = {03622525},

year  = {2023},

date = {2023-01-01},

journal = {Journal of Morphology},

volume = {284},

number = {1},

publisher = {John Wiley and Sons Inc},

abstract = {Adult specimens or larvae of invertebrates used as food for vertebrates are often maintained close to gluten so they might become vectors for cereal proteins. However, the tissues and internal organs can respond differently in animals with different feeding habits. The midgut epithelium might be a first and sufficient barrier preventing uptake and effects of gluten on the whole body, while the fat body is the main organ that accumulates different xenobiotics. Good models for such research are animals that do not feed on gluten-rich products in their natural environment. The project's goal was to investigate alterations in the midgut epithelium and fat body of the herbivorous millipede Telodeinopus aoutii (Diplopoda) and analyze cell death processes activated by gluten. It enabled us to determine whether changes were intensified or reversed by adaptive mechanisms. Adult specimens were divided into control and experimental animals fed with mushrooms supplemented with gluten and analyzed using transmission electron microscopy, flow cytometry, and confocal microscopy. Two organs were isolated for the qualitative and quantitative analysis: the midgut and the fat body. Our study of the herbivorous T. aoutii which does not naturally feed on gluten containing diet showed that continuous and prolonged gluten feeding activates repair processes that inhibit the processes of cell death (apoptosis and necrosis) and induce an increase in cell viability. © 2022 Wiley Periodicals LLC.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-85128842423,

title = {Ovaries and testes of Lithobius forficatus (Myriapoda, Chilopoda) react differently to the presence of cadmium in the environment},

author = { I. Poprawa and Ł. Chajec and A. Chachulska-Żymełka and G. Wilczek and S. Student and M. Leśniewska and M.M. Rost-Roszkowska},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85128842423&doi=10.1038%2fs41598-022-10664-4&partnerID=40&md5=8b63d068ae6726dff9844ca0d4a93be1},

doi = {10.1038/s41598-022-10664-4},

issn = {20452322},

year  = {2022},

date = {2022-01-01},

journal = {Scientific Reports},

volume = {12},

number = {1},

publisher = {Nature Research},

abstract = {Proper reproduction depends on properly functioning gonads (ovaries and testes). Many xenobiotics, including heavy metals, can cause changes in somatic and germ line cells, thus damaging the reproductive capacity. The aim of this study was to investigate the effect of the heavy metal cadmium on the gonads, including germ line and somatic cells. It is important to determine whether cell death processes are triggered in both types of cells in the gonads, and which gonads are more sensitive to the presence of cadmium in the environment. The research was conducted on the soil-dwelling arthropod Lithobius forficatus (Myriapoda; Chilopoda), which is common for European fauna. Animals were cultured in soil supplemented with Cd for different periods (short- and long-term treatment). Gonads were isolated and prepared for qualitative and quantitative analysis, which enabled us to describe all changes which appeared after both the short- and long-term cadmium treatment. The results of our study showed that cadmium affects the structure and ultrastructure of both gonads in soil-dwelling organisms including the activation of cell death processes. However, the male germ line cells are more sensitive to cadmium than female germ line cells. We also observed that germ line cells are protected by the somatic cells of both gonads. © 2022, The Author(s).},

note = {3},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-85134226759,

title = {Hazards related to the presence of cadmium in food – Studies on the European soil centipede, Lithobius forficatus},

author = { M.M. Rost-Roszkowska and I. Poprawa and Ł. Chajec and A. Chachulska-Żymełka and G. Wilczek and M. Skowronek and S. Student and M. Leśniewska},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85134226759&doi=10.1016%2fj.scitotenv.2022.157298&partnerID=40&md5=3e44db2c8124fdeab23b618b4495900f},

doi = {10.1016/j.scitotenv.2022.157298},

issn = {00489697},

year  = {2022},

date = {2022-01-01},

journal = {Science of the Total Environment},

volume = {845},

publisher = {Elsevier B.V.},

abstract = {The soil is an environment rich in numerous potentially toxic substances/elements when present at elevated concentrations. They can be transported through the successive levels of the trophic chain. Animals living in a contaminated environment or eating contaminated food can accumulate potentially toxic elements in their bodies. One of the potentially toxic metals is cadmium, which accumulates significantly in soils. The aim of our research was to evaluate the changes caused by cadmium supplied with the food administered to invertebrates living in uncontaminated soil. The results were compared with those obtained for animals raised in contaminated soil, where cadmium entered the body via the epidermis. As the material for studies, we chose a common European soil centipede, Lithobius forficatus. Adult specimens were divided into the following experimental groups: C – control animals, Cd12 and Cd45 – animals fed with Chironomus larvae maintained in water containing 80 mg/l CdCl2, for 12 and 45 days, respectively. The material was analyzed using qualitative and quantitative analysis (transmission electron microscopy; confocal microscopy; flow cytometry; atomic absorption spectrometry). Eventually, we can conclude that the digestive system is an effective barrier against the effects of toxic metals on the entire organism, but among the gonads, ovaries are more protected than testes, however, this protection is not sufficient. Accumulation of spherites and mitochondrial alterations are probably involved in survival mechanisms of tissues after Cd intoxication. © 2022},

note = {2},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-85149772138,

title = {Assessment of the knowledge of clients of beauty salons about treatments with the use of hyaluronic acid and their impact on skin revitalization [Ocena wiedzy klientek salonów kosmetycznych na temat zabiegów z wykorzystaniem kwasu hialuronowego i ich wpływu na rewitalizację skóry]},

author = { A. Aleksa and M.M. Rost-Roszkowska},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85149772138&doi=10.52336%2facm.2022.011&partnerID=40&md5=f7209abba5b5ce88685e997a2018137d},

doi = {10.52336/acm.2022.011},

issn = {27193241},

year  = {2022},

date = {2022-01-01},

journal = {Aesthetic Cosmetology and Medicine},

volume = {11},

number = {2},

pages = {65-73},

publisher = {INDYGO Zahir Media},

abstract = {Skin aging is a natural, physiological and inevitable process. Today, many women strive to keep their young appearance as long as possible. The knowledge of women about the factors accelerating or slowing down the aging process of the skin is growing. Hyaluronic acid is a substance widely used in modern cosmetology and is one of the most valued on the aesthetic market due to its high biocompatibility and low toxicity. It maintains proper hydration, a healthy and youthful appearance of the skin. It occurs naturally in the human body and other living organisms and it is a crucial element of both cosmetic and aesthetic medicine treatments. Hyaluronic acid is a component of cosmetics used externally in preparations intended for home care. Therapies with HA support the counteraction against such skin defects as wrinkles, dry skin, loss of skin elasticity and firmness, scars, stretch marks, cellulite, burns, and wounds. Women are aware of the effects of hyaluronic acid on the skin. The aim of this study was to examine the knowledge of clients of beauty salons about treatments with the use of hyaluronic acid and their impact on skin revitalization. The study was achieved by conducting a proprietary questionnaire checking the knowledge of female respondents about hyaluronic acid and its use in anti-aging therapy. By analyzing the obtained results, it can be concluded that women have basic knowledge of hyaluronic acid. © 2022 by the Author(s).},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-85124244211,

title = {Can insecticide-free clean water regenerate the midgut epithelium of the freshwater shrimp after dimethoate treatment?},

author = { A. Ostróżka and Z. Tiffert and G. Wilczek and M.M. Rost-Roszkowska},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85124244211&doi=10.1016%2fj.micron.2021.103162&partnerID=40&md5=8e8f25bae5caedee6ed162aa6f89a051},

doi = {10.1016/j.micron.2021.103162},

issn = {09684328},

year  = {2022},

date = {2022-01-01},

journal = {Micron},

volume = {155},

publisher = {Elsevier Ltd},

abstract = {Insecticides such as dimethoate persist for a long time in freshwater environments, influencing the physiology of the animals inhabiting such environments. In aquatic organisms, toxic substances can enter the body through the epidermis and the digestive system. The midgut is part of this system in which intense processes constitute a barrier against the effects of toxic substances on the body. The aim of this study was to evaluate the toxic potential of dimethoate in the midgut epithelium of the freshwater shrimp Neocaridina davidi, emphasizing ultrastructural alterations. However, the additional and main purpose was to determine whether the midgut epithelium can regenerate after placing animals in insecticide-free clean water after various periods of exposure to dimethoate. N. davidi originates from Asia, but it has also been described in European rivers. This species is of particular interest among breeders worldwide due to its ease of breeding and reproduction. The animals were treated with dimethoate for 1, 2, and 3 weeks and then placed in clean water for 1, 2, and 3 weeks. The qualitative and quantitative analysis revealed different sensitivity of organs forming the midgut in freshwater crustaceans and the possibility for midgut regeneration after insecticide exposure. We concluded that different processes were triggered in the intestine and hepatopancreas to regenerate cells after damage, and mitochondria were the first organelles to respond to the appearance of a stressor in the living environment. © 2021 The Authors},

note = {3},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-85120968815,

title = {The effect of selected immunostimulants on hemocytes of the false black widow Steatoda grossa (Theridiidae) spiders under chronic exposition to cadmium},

author = { K. Wiśniewska and M.M. Rost-Roszkowska and J. Homa and K. Kasperkiewicz and K. Surmiak-Stalmach and E. Szulińska and G. Wilczek},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85120968815&doi=10.1016%2fj.cbpc.2021.109221&partnerID=40&md5=a540ad597a3ee7233969b92b35b3305d},

doi = {10.1016/j.cbpc.2021.109221},

issn = {15320456},

year  = {2022},

date = {2022-01-01},

journal = {Comparative Biochemistry and Physiology Part - C: Toxicology and Pharmacology},

volume = {252},

publisher = {Elsevier Inc.},

abstract = {The aim of this study was to analyze whether, and to what extent, long–term exposure to cadmium, administered in sublethal concentrations by the oral route, caused changes in the immune potential of hemocytes in adult female Steatoda grossa spiders. We used artificial and natural immunostimulants, namely phorbol 12–myristate 13–acetate (PMA) and bacterial cell suspension based on Gram–positive (G+; Staphylococcus aureus) and Gram–negative (G−; Pseudomonas fluorescens) bacteria, to compare the status of hemocytes in nonstimulated individuals and those subjected to immunostimulation. After cadmium exposure, the percentage of small nongranular hemocytes in response to G+ cell suspension and PMA mitogen was decreased. Furthermore, in the cadmium–intoxicated spiders the percentage of plasmatocytes after immunostimulation remained lower compared to the complementary control group. Exposure to cadmium also induced several degenerative changes, including typical apoptotic and necrotic changes, in the analyzed types of cells. Immunostimulation by PMA mitogen and G+ bacterial suspension resulted in an increase in the number of cisterns in the rough endoplasmic reticulum of granulocytes, in both the control group and cadmium–treated individuals. These changes were accompanied with a low level of metallothioneins in hemolymph. Chronic cadmium exposure may significantly weaken the immune defense system of spiders during infections. © 2021 Elsevier Inc.},

note = {4},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-85109750684,

title = {Changes in the avascular area of the meniscus using mesenchymal stem cells and growth plate chondrocytes in a pig model},

author = { R. Tomaszewski and M.M. Rost-Roszkowska and G. Wilczek and A. Gap and Ł. Wiktor},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85109750684&doi=10.1111%2fjoa.13508&partnerID=40&md5=abd18f892229d99ef33b1719243ee404},

doi = {10.1111/joa.13508},

issn = {00218782},

year  = {2021},

date = {2021-01-01},

journal = {Journal of Anatomy},

volume = {239},

number = {6},

pages = {1409-1418},

publisher = {John Wiley and Sons Inc},

abstract = {Menisci are wedge-shaped cartilage discs that are divided into two parts: the avascular and vascular regions. They are formed by fibrocartilage tissue, which contains round cartilage-like cells and extracellular matrix. Meniscus injury in animals is a common orthopedic problem, but data on the natural healing process mainly deals with the vascular zone. The healing processes in the avascular zone of the meniscus are significantly limited. Thus, this study aimed to evaluate autologous growth plate chondrocytes' impact on the healing process of a damaged meniscus in the avascular zone based on a growing animal model. The study group consisted of 10 pigs at about three months of age. From each animal, chondrocytes from the iliac growth plate and from concentrated bone marrow were taken. Knee joints were divided into right (R) and left (L). The medial meniscus of the R knee joint was treated with a hyaluronic acid based scaffold incubated with bone marrow cells from marrow aspirates (nCHON). The medial meniscus of the L knee joint was treated with a hyaluronic acid based scaffold incubated with bone marrow cells from marrow aspirates supplemented with immature chondrocytes isolated from growth plates (wCHON). The meniscus was damaged in the avascular zone in both knee joints. Followingly, the damaged part of the meniscus was filled with a scaffold with cells from the concentrated bone marrow and from growth plate chondrocytes. In the control group, a scaffold with concentrated bone marrow cells was used. After three months the animals were euthanized and preparations (microscopic slides) were made from the meniscus' damaged part. A qualitative and quantitative analysis have been prepared. The wCHON group in comparison with the nCHON group showed a statistically significantly higher number of fusiform cells on the surface of the graft as well as better healing of the graft. In addition, the degree of vascularization was higher in specimens from the wCHON group than in the nCHON group. The results of our research on immature pig knees revealed that mesenchymal stem cell and growth plate chondrocytes could be treated as the cell source for meniscus reconstruction, and growth plate chondrocytes enhance healing processes in the avascular zone of the injured meniscus. © 2021 Anatomical Society},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-85112328133,

title = {Structure of the midgut epithelium in four diplopod species: histology, histochemistry and ultrastructure},

author = { M.M. Rost-Roszkowska and J. Vilimová and K. Tajovský and V. Šustr and A. Ostróżka and F. Kaszuba},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85112328133&doi=10.3897%2fASP.79.E67022&partnerID=40&md5=e03fc427483f12cafaa72bc2fd759d15},

doi = {10.3897/ASP.79.E67022},

issn = {18637221},

year  = {2021},

date = {2021-01-01},

journal = {Arthropod Systematics and Phylogeny},

volume = {79},

pages = {295-308},

publisher = {Staatliche Naturhistorische Sammlungen Dresden},

abstract = {The middle region of the digestive system of millipedes, the midgut, is responsible for all processes connected with digestion, but also takes part in homeostasis maintenance thanks to the ability to activate many mechanisms which neutralize changes occurring at different levels of the animal’s body. Numerous millipede species are treated as bioindicators of the natural environment and they are exposed to different stressors which originate from external environment. To obtain all data on the functioning of midgut of millipedes as the barrier against stressors, it is necessary to have a precise and general description of the midgut epithelium. Members from four millipede orders were selected for the studies: Polydesmus angustus (Polydesmida), Epibolus pulchripes (Spirobolida), Unciger transsilvanicus (Julida) and Glomeris tetrasticha (Glomerida). The structure and ultrastructure of their midgut epithelial cells (the digestive; secretory and regenerative cells) were documented using transmission electron microscopy and histochemical methods. The obtained results have been compared and discussed to previous ones, to present the general and structural organization of the midgut in Diplopoda. Our studies revealed that the ultrastructure of all cells which form the midgut epithelium in millipedes is general for all the species studied up to now and it resembles the cell ultrastructure observed in Chilopoda and Hexapoda, including the digestive, secretory and stem cells. © 2021. All Rights Reserved.},

note = {2},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-85105631786,

title = {Effects of cadmium on mitochondrial structure and function in different organs: studies on the soil centipede Lithobius forficatus (Myriapoda, Chilopoda)},

author = { M.M. Rost-Roszkowska and I. Poprawa and Ł. Chajec and A. Chachulska-Żymełka and G. Wilczek and P. Wilczek and M. Tarnawska and S. Student and M. Leśniewska},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85105631786&doi=10.1080%2f24750263.2021.1912199&partnerID=40&md5=521cb3648cd8129014a1058fea253b44},

doi = {10.1080/24750263.2021.1912199},

issn = {24750263},

year  = {2021},

date = {2021-01-01},

journal = {European Zoological Journal},

volume = {88},

number = {1},

pages = {632-648},

publisher = {Taylor and Francis Ltd.},

abstract = {Mitochondria are organelles that play a crucial role in cell physiology, cell death, and aging. They are among the first responders to different stressors that originate from the environment. Cadmium as a heavy metal affects different levels of body organization: from organs through tissues and cells to organelles. Based on our previous research results, we decided to check how the exposure to cadmium affects the functioning of mitochondria in different organs of soil living centipede Lithobius forficatus. The activity of mitochondria in somatic and germ cells has been analyzed using transmission electron microscopy (TEM), confocal microscopy, and flow cytometry. Changes in the mitochondrial membrane potential and mitochondrial dismutase (MnSOD) activity in relation to the accumulation of reactive oxygen species (ROS) caused by cadmium exposure have been studied. Individuals were divided into 3 experimental groups depending on cadmium concentration in soil. Changes in mitochondrial ultrastructure caused by cadmium are tissue-dependent and associated with an increase of ROS levels. The system of ROS and MnSOD activation works more efficiently in the case of gonads than in the digestive system. While the short-term cadmium exposure alters the fine structure of both the somatic and germ-line cells in gonads, the long-term cadmium exposure causes mitochondrial ultrastructure regeneration. © 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.},

note = {2},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-85099868244,

title = {The activity of hydrolytic enzymes in the digestive system of Acanthobdellida, Branchiobdellida and Hirudinida (Annelida, Clitellata)–considerations on similarity and phylogeny},

author = { J.M. Cichocka and A. Bielecki and P. Świątek and I. Jabłońska-Barna and J. Kobak and J. Hildebrand and M. Dmitryjuk and W. Strużyński and M.M. Rost-Roszkowska},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85099868244&doi=10.1080%2f24750263.2020.1851402&partnerID=40&md5=743f9aa03cd10f5d9db1444c9a1a648d},

doi = {10.1080/24750263.2020.1851402},

issn = {24750263},

year  = {2021},

date = {2021-01-01},

journal = {European Zoological Journal},

volume = {88},

number = {1},

pages = {26-43},

publisher = {Taylor and Francis Ltd.},

abstract = {Activities of nineteen hydrolases were measured in the digestive systems of predatory and blood-feeding true leeches (Hirudinida) and their closest relatives, Branchiobdellida and Acanthobdellida. Hydrolase activities were analyzed in different parts of the digestive systems: the species-specific anterior part, i.e. jaws, pharynx or proboscis, crop and intestine. The results obtained suggest that food digestion and possible absorption predominate in the intestine of most of the studied Hirudinida and A. peledina, whereas in B. astaci these processes take place in the anterior part of the digestive system and crop. In Erpobdellidae and Piscicola respirans, the activity of acid and alkaline phosphatases, N-acetyl-β-glucosaminidase, leucine and valine arylamidases, and α-fucosidase was also detected in the anterior part of the digestive system. We also detected differences in enzyme occurrence between the studied species, which are probably connected with their different food preferences. Moreover, the presence of the whole spectrum of enzymes in predatory leeches and the absence of trypsin and α-chymotrypsin activity in the crop of all the leeches support the hypothesis that the leech ancestor was a blood-feeder. Our study showed that “Rhynchobdellida” constitute a paraphyletic group which confirms the previous results based on molecular phylogenetics, while Arhynchobdellida appears to be a non-monophyletic group which is not consistent with previous molecular results. © 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.},

note = {2},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-85092623504,

title = {Postembryonic development and differentiation of the midgut in the freshwater shrimp Neocaridina davidi (Crustacea, Malacostraca, Decapoda) larvae},

author = { L. Sonakowska-Czajka and J. Śróbka and A. Ostróżka and M.M. Rost-Roszkowska},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85092623504&doi=10.1002%2fjmor.21281&partnerID=40&md5=c6fe50316c339b4b40c6adedb7ff9bf3},

doi = {10.1002/jmor.21281},

issn = {03622525},

year  = {2021},

date = {2021-01-01},

journal = {Journal of Morphology},

volume = {282},

number = {1},

pages = {48-65},

publisher = {John Wiley and Sons Inc},

abstract = {Neocaridina davidi is a freshwater shrimp that originates from Taiwan and is commonly bred all over the word. Like all decapods, which develop indirectly, this species has pelagic larvae that may differ entirely in their morphology and habits from adult specimens. To fill a gap of knowledge about the developmental biology of freshwater shrimps we decided to document the 3D-localization of the midgut inside the body cavity of larval stages of N. davidi using X-ray microtomography, and to describe all structural and ultrastructural changes of the midgut epithelium (intestine and hepatopancreas) which occur during postembryonic development of N. davidi using light and transmission electron microscopy. We laid emphasis on stem cell functioning and cell death processes connected with differentiation. Our study revealed that while the intestine in both larval stages of N. davidi has the form of a fully developed organ, which resembles that of adult specimens, the hepatopancreas undergoes elongation and differentiation. E-cells, which are midgut stem cells, due to their proliferation and differentiation are responsible for the above-mentioned processes. Our study revealed that apoptosis is a common process in both larval stages of N. davidi in the intestine and proximal region of the hepatopancreas. In zoea III, autophagy as a survival factor is activated in order to protect cells against their death. However, when there are too many autophagic structures in epithelial cells, necrosis as passive cell death is activated. The presence of all types of cell death in the midgut in the zoea III stage confirms that this part of the digestive tract is fully developed and functional. Here, we present the first description of apoptosis, autophagy and necrosis in the digestive system of larval stages of Malacostraca and present the first description of their hepatopancreas elongation and differentiation due to midgut stem cell functioning. © 2020 Wiley Periodicals LLC.},

note = {7},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-85097069721,

title = {Autophagy: a necessary defense against extreme cadmium intoxication in a multigenerational 2D experiment},

author = { A. Babczyńska and A. Nowak and A. Kafel and B. Łozowski and M.M. Rost-Roszkowska and M. Tarnawska and M. Augustyniak and M.K. Sawadro and A.E. Molenda},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85097069721&doi=10.1038%2fs41598-020-78316-z&partnerID=40&md5=7ec842d0f44a16b6784907a0728b2823},

doi = {10.1038/s41598-020-78316-z},

issn = {20452322},

year  = {2020},

date = {2020-01-01},

journal = {Scientific Reports},

volume = {10},

number = {1},

publisher = {Nature Research},

abstract = {Autophagy is a natural process that aims to eliminate malfunctioning cell parts, organelles or molecules under physiological conditions. It is also induced in response to infection, starvation or oxidative stress to provide energy in case of an energy deficit. The aim of this 2-dimensional study was to test if, and if so, how, this process depends on the concentration of cadmium in food (with Cd concentrations from 0 to 352 μg of Cd per g of food (dry weight)—D1 dimension) and the history of selection pressure (160 vs 20 generations of exposure to Cd—D2 dimension). For the study, the 5th instar larvae of a unique strain of the moth Spodoptera exigua that was selected for cadmium tolerance for 160 generations (44 μg of Cd per g of food (dry weight)), as well as 20-generation (11; 22 and 44 μg of Cd per g of food (dry weight)) and control strains, were used. Autophagy intensity was measured by means of flow cytometry and compared with life history parameters: survivability and duration of the 3rd larval stage. The highest values of autophagy markers were found in the groups exposed to the highest Cd concentration and corresponded (with a significant correlation coefficient) to an increased development duration or decreased survivorship in the respective groups. In conclusion, autophagy is probably initiated only if any other defense mechanisms, e.g., antioxidative mechanisms, are not efficient. Moreover, in individuals from pre-exposed populations, the intensity of autophagy is lower. © 2020, The Author(s).},

note = {2},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-85088645994,

title = {DNA damage in Spodoptera exigua after multigenerational cadmium exposure - A trade-off between genome stability and adaptation},

author = { M. Augustyniak and M. Tarnawska and M. Dziewięcka and A. Kafel and M.M. Rost-Roszkowska and A. Babczyńska},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85088645994&doi=10.1016%2fj.scitotenv.2020.141048&partnerID=40&md5=8e46a0514984c19ad9d2fba14b49e9bf},

doi = {10.1016/j.scitotenv.2020.141048},

issn = {00489697},

year  = {2020},

date = {2020-01-01},

journal = {Science of the Total Environment},

volume = {745},

publisher = {Elsevier B.V.},

abstract = {Human activity is a serious cause of extensive changes in the environment and a constant reason for the emergence of new stress factors. Thus, to survive and reproduce, organisms must constantly implement a program of adaptation to continuously changing conditions. The research presented here is focused on tracking slow changes occurring in Spodoptera exigua (Lepidoptera: Noctuidae) caused by multigenerational exposure to sub-lethal cadmium doses. The insects received food containing cadmium at concentrations of 5, 11, 22 and 44 μg per g of dry mass of food. The level of DNA stability was monitored by a comet assay in subsequent generations up to the 36th generation. In the first three generations, the level of DNA damage was high, especially in the groups receiving higher doses of cadmium in the diet. In the fourth generation, a significant reduction in the level of DNA damage was observed, which could indicate that the desired stability of the genome was achieved. Surprisingly, however, in subsequent generations, an alternating increase and decrease was found in DNA stability. The observed cycles of changing DNA stability were longer lasting in insects consuming food with a lower Cd content. Thus, a transient reduction in genome stability can be perceived as an opportunity to increase the number of genotypes that undergo selection. This phenomenon occurs faster if the severity of the stress factor is high but is low enough to allow the population to survive. © 2020 Elsevier B.V.},

note = {11},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-85087489337,

title = {Effects of short- and long-term exposure to cadmium on salivary glands and fat body of soil centipede Lithobius forficatus (Myriapoda, Chilopoda): Histology and ultrastructure},

author = { M.M. Rost-Roszkowska and I. Poprawa and Ł. Chajec and A. Chachulska-Żymełka and M. Leśniewska and S. Student},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85087489337&doi=10.1016%2fj.micron.2020.102915&partnerID=40&md5=6309db2f521f14d140f64b2f7000a299},

doi = {10.1016/j.micron.2020.102915},

issn = {09684328},

year  = {2020},

date = {2020-01-01},

journal = {Micron},

volume = {137},

publisher = {Elsevier Ltd},

abstract = {Cadmium (Cd) is the most widely studied heavy metal in terms of food-chain accumulation and contamination because it can strongly affect all environments (e.g.; soil; water; air). It can accumulate in different tissues and organs and can affect the organism at different levels of organization: from organs, tissues and cells though cell organelles and structures to activation of mechanisms of survival and cell death. In soil-dwelling organisms heavy metals gather in all tissues with accumulation properties: midgut, salivary glands, fat body. The aim of this study was to describe the effects of cadmium on the soil species Lithobius forficatus, mainly on two organs responsible for gathering different substances, the fat body and salivary glands, at the ultrastructural level. Changes caused by cadmium short- and long-term intoxication, connected with cell death (autophagy; apoptosis; necrosis), and the crosstalk between them, were analyzed. Adult specimens of L. forficatus were collected in a natural environment and divided into three experimental groups: C (the control group), Cd1 (cultured in soil with 80 mg/kg of CdCl2 for 12 days) and Cd2 (cultured in soil with 80 mg/kg of CdCl2 for 45 days). Transmission electron microscopy revealed ultrastructural alterations in both of the organs analyzed (reduction in the amount of reserve material; the appearance of vacuoles; etc.). Qualitative analysis using TUNEL assay revealed distinct crosstalk between autophagy and necrosis in the fat body adipocytes, while crosstalk between autophagy, apoptosis and necrosis in the salivary glands was detected in salivary glands of the centipedes examined here. We conclude that different organs in the body can react differently to the same stressor, as well as to the same concentration and time of exposure. Different mechanisms at the ultrastructural level activate different types of cell death and with different dynamics. © 2020 Elsevier Ltd},

note = {4},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-85083788720,

title = {Graphene oxide as a new anthropogenic stress factor - multigenerational study at the molecular, cellular, individual and population level of Acheta domesticus},

author = { M. Dziewięcka and B. Flasz and M.M. Rost-Roszkowska and A. Kędziorski and A. Kochanowicz and M. Augustyniak},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85083788720&doi=10.1016%2fj.jhazmat.2020.122775&partnerID=40&md5=4c5ac8dd6643714067dd963491c30c94},

doi = {10.1016/j.jhazmat.2020.122775},

issn = {03043894},

year  = {2020},

date = {2020-01-01},

journal = {Journal of Hazardous Materials},

volume = {396},

publisher = {Elsevier B.V.},

abstract = {Although interest in transgenerational phenomena is constantly growing, little is known about the long-term toxicity of nanoparticles. In this study we investigate the multigenerational effects of graphene oxide (GO) which was given to Acheta domesticus in low doses (0.2; 2 and 20 μg·g-1 of food) for three subsequent generations. We assessed the influence of GO nanoparticles in many contexts, basing on parameters which represented different levels of biological organization: activity of antioxidant enzymes, level of apoptosis, DNA damage, histological analysis, hatching abilities, body mass and body length of insects, as well as their survival rate. The results have shown that exposing insects to nanoparticles over an extended period of time causes surprising intergenerational effects, based on significant differences in the life cycle and reproductive processes, which are not always dose-dependent. The second generation of insects appeared as the most unstable among the parameters that were studied, and did not match trends and patterns in the first and third generation categories. An increase of DNA damage was observed, but only in the third generation. This reduction of genome stability can be perceived as an essential element of adaptation, leading to an increase of genotype variants, which then undergo selection. © 2020 Elsevier B.V.},

note = {16},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-85075281812,

title = {Enzymatic activities in the digestive tract of spirostreptid and spirobolid millipedes (Diplopoda: Spirostreptida and Spirobolida)},

author = { V. Šustr and S. Semanová and M.M. Rost-Roszkowska and K. Tajovský and A. Sosinka and F. Kaszuba},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85075281812&doi=10.1016%2fj.cbpb.2019.110388&partnerID=40&md5=81875be3727b690bdc14d9c10aaf86f8},

doi = {10.1016/j.cbpb.2019.110388},

issn = {10964959},

year  = {2020},

date = {2020-01-01},

journal = {Comparative Biochemistry and Physiology Part - B: Biochemistry and Molecular Biology},

volume = {241},

publisher = {Elsevier Inc.},

abstract = {Millipedes represent a model for the study of organic matter transformation, animal-microbial interactions, and compartmentalisation of digestion. The activity of saccharidases (amylase; laminarinase; cellulase; xylanase; chitinase; maltase; cellobiase; and trehalase) and protease were measured in the midgut and hindgut contents and walls of the millipedes Archispirostreptus gigas and Epibolus pulchripes. Assays done at pH 4 and 7 confirmed activities of all enzymes except xylanase. Hydrolysing of starch and laminarin prevailed. The hindgut of E. pulchripes was shorter, less differentiated. Micro-apocrine secretion was observed only in the midgut of A. gigas. Merocrine secretion was present in midgut and hindgut of E. pulchripes, and in the pyloric valve and anterior hindgut of A. gigas. Alpha-polysaccharidases were mostly active in the midgut content and walls, with higher activity at pH 4. The low activity of amylase (A. gigas) and laminarinase (E. pulchripes) in midgut tissue may indicate their synthesis in salivary glands. Cellulases were found in midgut. Chitinases, found in midgut content and tissue (E. pulchripes) or concentrated in the midgut wall (A. gigas), were more active at an acidic pH. Polysaccharidases were low in hindguts. Protease shows midgut origin and alkaline activity extending to the hindgut in E. pulchripes, whereas in A. gigas it is of salivary gland origin and acid activity restricted to the midgut. Some disaccharidases, with more alkaline activity, showed less apparent midgut-hindgut differences. It may indicate an axial separating of the primary and secondary digestion along the intestinal pH gradient or the presence of enzymes of hindgut parasites. © 2019},

note = {5},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-85086015206,

title = {Influence of soil contaminated with cadmium on cell death in the digestive epithelium of soil centipede Lithobius forficatus (Myriapoda, Chilopoda)},

author = { M.M. Rost-Roszkowska and I. Poprawa and Ł. Chajec and A. Chachulska-Żymełka and G. Wilczek and P. Wilczek and S. Student and M. Skowronek and A. Nadgórska-Socha and M. Leśniewska},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85086015206&doi=10.1080%2f24750263.2020.1757168&partnerID=40&md5=58f49682d112d8cec5ea24fe0e5c2b11},

doi = {10.1080/24750263.2020.1757168},

issn = {24750263},

year  = {2020},

date = {2020-01-01},

journal = {European Zoological Journal},

volume = {87},

number = {1},

pages = {242-262},

publisher = {Taylor and Francis Ltd.},

abstract = {Cadmium is a heavy metal that is treated as an environmental pollutant (air; water; soil). In order to understand the potential effects of cadmium in soil and soil invertebrates, it is important to describe all alterations which appear at different levels in organisms. The main aim of this study was to investigate, analyze and describe the alterations caused by cadmium short- and long-term intoxication at different levels in the organisms: from tissues to cells and organelles. In addition, the activation of cell death mechanisms that take part in homeostasis maintenance according to cadmium has been studied. Therefore, as the species for this project, a terrestrial and well-known widespread European species–the centipede Lithobius forficatus (Myriapoda; Chilopoda; Lithobiomorpha)–was chosen. This omnivorous species lives under upper layers of soil, under stones, litter, rocks, and leaves, and it is also commonly found in human habitats. The animals were divided into three groups: C–the control group, animals cultured in a horticultural soil; Cd1–animals cultured in a horticultural soil supplemented with 80 mg/kg (dry weight) of CdCl2, 12 days–short-term exposure; Cd2–animals cultured in a horticultural soil supplemented with 80 mg/kg (dry weight) of CdCl2, 45 days–long-term exposure. The midgut was isolated from each specimen and it was prepared for analysis using some histological, histochemical and immunohistochemical methods. Our studies showed that short-term intoxication causes intensification of autophagy and digestion of reserve material, while long-term exposure to this heavy metal causes activation of cell death processes together with inhibition of autophagy connected with the lack of reserve material. Additionally, we can infer that autophagy and cell death are nutrient deprivation-induced processes. Finally, we can conclude that short- and long-term exposure of soil centipede to cadmium affects different mechanisms and processes of cell death. © 2020, © 2020 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.},

note = {9},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-85083692263,

title = {Ultrastructure of the midgut epithelium in three species of Macrobiotidae (Tardigrada: Eutardigrada: Parachela)},

author = { M.M. Rost-Roszkowska and K. Janelt and I. Poprawa},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85083692263&doi=10.1093%2fzoolinnean%2fzlz052&partnerID=40&md5=98795359bf5de4e4ae3ec09aa4a9f4bf},

doi = {10.1093/zoolinnean/zlz052},

issn = {00244082},

year  = {2020},

date = {2020-01-01},

journal = {Zoological Journal of the Linnean Society},

volume = {188},

number = {3},

pages = {788-796},

publisher = {Oxford University Press},

abstract = {Three species of Macrobiotidae, Macrobiotus polonicus, Macrobiotus diversus and Macrobiotus pallarii, were selected for analysis of the fine structure of the midgut epithelium. They are gonochoric and carnivorous species that live in wet terrestrial and freshwater environments. The ultrastructure of the midgut epithelium of the investigated Macrobiotidae species was analysed in both males and females. Their digestive system is composed of fore- and hindguts that are covered by a cuticle, and the middle region, termed the midgut. It is lined with a simple epithelium that is formed by digestive cells that have a distinct brush border. Crescent-shaped cells that form an anterior ring in the border between the fore- and midgut were detected. The ultrastructure of the intestinal epithelium of the examined species differs slightly depending on sex. The digestive cells of the posterior segment of the intestine contain numerous lipid droplets, which are the reserve material. We concluded that the digestive cells of the Macrobiotidae midgut are responsible for its intracellular digestion owing to endocytosis. They also participate in the extracellular digestion owing to merocrine secretion (exocytosis). However, the midgut is not the main organ that accumulates reserve material. Additionally, the midgut epithelium does not participate in oogenesis. © 2019 The Linnean Society of London},

note = {2},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-85064267438,

title = {Microevolution or wide tolerance? Level of stress proteins in the beet armyworm Spodoptera eqigua hübner (Lepidoptera: Noctuidae) exposed to cadmium for over 150 generations},

author = { M. Tarnawska and A. Kafel and M. Augustyniak and M.M. Rost-Roszkowska and A. Babczyńska},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85064267438&doi=10.1016%2fj.ecoenv.2019.04.017&partnerID=40&md5=5f3adb3246bf4dcbd5777ca3f52fe722},

doi = {10.1016/j.ecoenv.2019.04.017},

issn = {01476513},

year  = {2019},

date = {2019-01-01},

journal = {Ecotoxicology and Environmental Safety},

volume = {178},

pages = {1-8},

publisher = {Academic Press},

abstract = {The aim of this study was to investigate whether the cadmium tolerance developed in the beet armyworm Spodoptera exigua selected for over 150 generations may be related to synthesis of the stress proteins metallothioneins (Mts) and 70 kDa heat shock proteins (HSP70). To achieve this, six S. exigua strains (control; k), 150-generation Cd exposure strain (cd), and four 18-generation Cd exposure strains differing in Cd concentration (cd44; cd22; cd11; cd5) were reared. Stress protein level was measured in the midgut of the 5th larval stage after 1–6, 12 and 18 generations. Cd contents was measured in the pupae. Unlike Cd concentration, which depended on metal contents in food but was not generation-dependent, the pattern of Mts and HSP70 concentrations changed in experimental strains from generation to generation. Stress protein levels in the insects exposed to the highest Cd concentration (the same as in the 150-generation Cd exposure strain), initially higher than in the control strain, after the 12th generation did not differ from the level measured in the control strains. It seems therefore that stress proteins play a protective role in insects of lower tolerance to cadmium. The tolerance developed during multigenerational exposure probably relies on mechanisms other than Mt and HSP70 synthesis. © 2019 Elsevier Inc.},

note = {12},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-85065912638,

title = {Autophagy and apoptosis in the midgut epithelium of millipedes},

author = { M.M. Rost-Roszkowska and J. Vilimová and K. Tajovský and A. Chachulska-Żymełka and A. Sosinka and M. Kszuk-Jendrysik and A. Ostróżka and F. Kaszuba},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85065912638&doi=10.1017%2fS143192761900059X&partnerID=40&md5=c61361bfea2cb26d1ebf674d1ed0a10d},

doi = {10.1017/S143192761900059X},

issn = {14319276},

year  = {2019},

date = {2019-01-01},

journal = {Microscopy and Microanalysis},

volume = {25},

number = {4},

pages = {1004-1016},

publisher = {Cambridge University Press},

abstract = {The process of autophagy has been detected in the midgut epithelium of four millipede species: Julus scandinavius, Polyxenus lagurus, Archispirostreptus gigas, and Telodeinopus aoutii. It has been examined using transmission electron microscopy (TEM), which enabled differentiation of cells in the midgut epithelium, and some histochemical methods (light microscope and fluorescence microscope). While autophagy appeared in the cytoplasm of digestive, secretory, and regenerative cells in J. scandinavius and A. gigas, in the two other species, T. aoutii and P. lagurus, it was only detected in the digestive cells. Both types of macroautophagy, the selective and nonselective processes, are described using TEM. Phagophore formation appeared as the first step of autophagy. After its blind ends fusion, the autophagosomes were formed. The autophagosomes fused with lysosomes and were transformed into autolysosomes. As the final step of autophagy, the residual bodies were detected. Autophagic structures can be removed from the midgut epithelium via, e.g., atypical exocytosis. Additionally, in P. lagurus and J. scandinavius, it was observed as the neutralization of pathogens such as Rickettsia-like microorganisms. Autophagy and apoptosis ca be analyzed using TEM, while specific histochemical methods may confirm it. © Microscopy Society of America 2019.},

note = {10},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-85057501676,

title = {Evaluation of selected biological properties of the hunting web spider (Steatoda grossa, Theridiidae) in the aspect of short- and long-term exposure to cadmium},

author = { G. Wilczek and J. Karcz and M.M. Rost-Roszkowska and A. Kędziorski and P. Wilczek and M. Skowronek and K. Wiśniewska and F. Kaszuba and K. Surmiak},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85057501676&doi=10.1016%2fj.scitotenv.2018.11.374&partnerID=40&md5=920625e28f19c9227a0da1dee9ae8325},

doi = {10.1016/j.scitotenv.2018.11.374},

issn = {00489697},

year  = {2019},

date = {2019-01-01},

journal = {Science of the Total Environment},

volume = {656},

pages = {297-306},

publisher = {Elsevier B.V.},

abstract = {The study aimed at comparing the effects of short- and long-term exposure of Steatoda grossa female spiders to cadmium on the web's architecture, its energy content, and ultrastructure of ampullate glands. Simple food chain model (medium with 0.25 mM CdCl 2 → Drosophila hydei flies → spider (for 4 weeks or 12 months) was used for the exposure. Analysis of Cd content provided evidence that silk fibers of the web are well protected against its incorporation irrespectively of the exposure period. Long-term exposure to cadmium resulted in the occurrence of numerous autophagosomes with degenerated organelles as well as apoptotic and necrotic cells in the ampullate glands. Concurrently; the individual silk fibers building double and multiple combination complexes were significantly thinner than in the control threads. Moreover; exposed spiders spun net with smaller mean calorific value than did the control individuals. Hence; evaluation of both the diameter of silk fibers and calorific value of the web can serve as biomarkers of the effects caused by exposure of these predators to cadmium. © 2018 Elsevier B.V.},

note = {11},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-85061080905,

title = {Ultrastructure of the fat body in the soil centipedes Lithobius forficatus (Lithobiidae) and Geophilus flavus (Geophilidae) according to their seasonal rhythms},

author = { K. Kamińska and S. Lipovšek and F. Kaszuba and M.M. Rost-Roszkowska},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85061080905&doi=10.1016%2fj.jcz.2019.01.004&partnerID=40&md5=3e937d4fb764090a718e2742aefd1980},

doi = {10.1016/j.jcz.2019.01.004},

issn = {00445231},

year  = {2019},

date = {2019-01-01},

journal = {Zoologischer Anzeiger},

volume = {279},

pages = {82-93},

publisher = {Elsevier GmbH},

abstract = {The behavior, metabolism and physiology of animals are regulated by seasonal and/or circadian rhythms. The main aim of this study was to describe all of the alterations that are connected with the structure, ultrastructure and histochemistry in the fat body according to the seasonal cycles in centipedes. We selected the common European and long-living centipedes Lithobius forficatus and Geophilus flavus (Myriapoda; Chilopoda) as the material for this study. The fat body, which is the organ that is responsible for the accumulation of organic and non-organic material, was isolated from adult males and females in three seasons – spring, summer and autumn. However, some of animals that were collected in the autumn, were placed in aquaria and kept in a refrigerator (the temperature was about 0–4 °C) in order to stimulate the winter. The analysis revealed that the fat body in both of the species of centipedes formed irregular lobular masses that were composed of adipocytes, which fill the hemocoel and surround the internal organs. The adipocytes are responsible for the accumulation of the reserve material; the main reserve material are lipids. However, some polysaccharides, mucopolysaccharides and proteins were also detected. Seasonal changes, which are primarily connected with the accumulation of the reserve material and organelles that are responsible for synthesis, occurred in the cytoplasm of the adipocytes. Additionally, there was a distinct relationship between the amount of reserve material, the number of vacuoles and the intensity of autophagy in the cytoplasm of the adipocytes. © 2019 Elsevier GmbH},

note = {2},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-85059464706,

title = {Fine structure of the midgut epithelium of Thulinius ruffoi (Tardigrada, Eutardigrada, Parachela) in relation to oogenesis and simplex stage},

author = { M.M. Rost-Roszkowska and K. Janelt and I. Poprawa},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85059464706&doi=10.1016%2fj.asd.2018.12.002&partnerID=40&md5=ebb830d538630fb7deaef04387168e72},

doi = {10.1016/j.asd.2018.12.002},

issn = {14678039},

year  = {2019},

date = {2019-01-01},

journal = {Arthropod Structure and Development},

volume = {49},

pages = {128-136},

publisher = {Elsevier Ltd},

abstract = {Thulinius ruffoi is a small freshwater tardigrade that lives in both non-polluted and polluted freshwater environments. As a result of tardigradan body miniaturization, the digestive system is reduced and simplified. It consists of a short fore- and hindgut, and the midgut in the shape of a short tube is lined with a simple epithelium. The midgut epithelium is formed by the digestive cells and two rings of crescent-shaped cells were also detected. The anterior ring is located at the border between the fore- and midgut, while the posterior ring is situated between the mid- and hindgut. The precise ultrastructure of the digestive and crescent-shaped cells was examined using transmission electron microscopy, serial block face scanning electron microscopy and histochemical methods. We analyzed the changes that occurred in the midgut epithelial cells according to oogenesis (the species is parthenogenetic and there were only females in the laboratory culture). We focused on the accumulation of reserve material and the relationship between this and the intensity of autophagy. We concluded that autophagy supplies energy during a natural period of starvation (the simplex stage) and delivers the energy and probably the substances that are required during oogenesis. Apoptosis was not detected in the midgut epithelium of T. ruffoi. © 2018 Elsevier Ltd},

note = {6},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-85074111126,

title = {Relationship between ROS production, MnSOD activation and periods of fasting and re-feeding in freshwater shrimp Neocaridina davidi (Crustacea, Malacostraca)},

author = { A. Włodarczyk and G. Wilczek and P. Wilczek and S. Student and A. Ostróżka and M. Tarnawska and M.M. Rost-Roszkowska},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85074111126&doi=10.7717%2fpeerj.7399&partnerID=40&md5=60bccc587e4acdd09cf38ccdc212914d},

doi = {10.7717/peerj.7399},

issn = {21678359},

year  = {2019},

date = {2019-01-01},

journal = {PeerJ},

volume = {2019},

number = {9},

publisher = {PeerJ Inc.},

abstract = {The middle region of the digestive system, the midgut of freshwater shrimp Neocaridina davidi is composed of a tube-shaped intestine and the hepatopancreas formed by numerous caeca. Two types of cells have been distinguished in the intestine, the digestive cells (D-cells) and regenerative cells (R-cells). The hepatopancreatic tubules have three distinct zones distinguished along the length of each tubule-the distal zone with R-cells, the medial zone with differentiating cells, and the proximal zone with F-cells (fibrillar cells) and B-cells (storage cells). Fasting causes activation of cell death, a reduction in the amount of reserve material, and changes in the mitochondrial membrane potential. However, here we present how the concentration of ROS changes according to different periods of fasting and whether re-feeding causes their decrease. In addition, the activation/deactivation of mitochondrial superoxide dismutase (MnSOD) was analyzed. The freshwater shrimps Neocaridina davidi (Crustacea; Malacostraca; Decapoda) were divided into experimental groups: animals starved for 14 days, animals re-fed for 4, 7, and 14 days. The material was examined using the confocal microscope and the flow cytometry. Our studies have shown that long-term starvation increases the concentration of free radicals and MnSOD concentration in the intestine and hepatopancreas, while return to feeding causes their decrease in both organs examined. Therefore, we concluded that a distinct relationship between MnSOD concentration, ROS activation, cell death activation and changes in the mitochondrial membrane potential occurred. Copyright © 2019 Włodarczyk et al.},

note = {7},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-85064083974,

title = {Autophagy and apoptosis in starved and refed Neocaridina davidi (Crustacea, Malacostraca) midgut},

author = { A. Włodarczyk and S. Student and M.M. Rost-Roszkowska},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85064083974&doi=10.1139%2fcjz-2018-0104&partnerID=40&md5=4da092af5c25d61ce45f18798dc04feb},

doi = {10.1139/cjz-2018-0104},

issn = {00084301},

year  = {2019},

date = {2019-01-01},

journal = {Canadian Journal of Zoology},

volume = {97},

number = {4},

pages = {294-303},

publisher = {Canadian Science Publishing},

abstract = {Adult specimens of the freshwater shrimp Neocaridina davidi Bouvier, 1904 (Crustacea) were starved for 7, 14, and 21 days. Specimens from the first and second experimental group were collected for the studies. The majority of animals starved for 21 days died. Additionally, some specimens from each group were refed for 4, 7, and 14 days. The epithelium of the midgut, which is composed of the intestine and hepatopancreas, was analyzed. While the epithelium of the intestine is formed by D-and R-cells, the epithelium of the hepatopancreas has R-, B-, and F-cells. Autophagy and apoptosis in the midgut epithelium were analyzed using transmission electron microscopy and immunohistochemical methods. These processes were only observed in the D-cells of the intestine and the F-and B-cells of the hepatopancreas. Starvation led to a reduction in the amount of reserve material in the B-cells. Although this process activated autophagy in both regions of the midgut, the intestine and hepatopancreas, after refeeding, the level of autophagy decreased. Starvation caused an increase in the apoptotic cells in both organs, while the refeeding caused a decrease in the number of apoptotic cells in both organs analyzed. Refeeding after periods of starvation caused an accumulation of reserve material in the hepatopancreas. © 2019, Canadian Science Publishing. All rights reserved.},

note = {9},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-85046726029,

title = {The role of autophagy in the midgut epithelium of Parachela (Tardigrada)},

author = { M.M. Rost-Roszkowska and K. Janelt and I. Poprawa},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85046726029&doi=10.1007%2fs00435-018-0407-x&partnerID=40&md5=0c5243383ecda419d277cc18238a6d9a},

doi = {10.1007/s00435-018-0407-x},

issn = {0720213X},

year  = {2018},

date = {2018-01-01},

journal = {Zoomorphology},

volume = {137},

number = {4},

pages = {501-509},

publisher = {Springer Verlag},

abstract = {The process of cell death has been detected in the midgut epithelium of four tardigrade species which belong to Parachela: Macrobiotus diversus, Macrobiotus polonicus, Hypsibius dujardini and Xerobiotus pseudohufelandi. They originated from different environments so they have been affected by different stressors: M. polonicus was extracted from a moss sample collected from a railway embankment; M. diversus was extracted from a moss sample collected from a petrol station; X. pseudohufelandi originated from sandy and dry soil samples collected from a pine forest; H. dujardini was obtained commercially but it lives in a freshwater or even in wet terrestrial environment. Autophagy is caused in the digestive cells of the midgut epithelium by different factors. However, a distinct crosstalk between autophagy and necrosis in tardigrades’ digestive system has been described at the ultrastructural level. Apoptosis has not been detected in the midgut epithelium of analyzed species. We also determined that necrosis is the major process that is responsible for the degeneration of the midgut epithelium of tardigrades, and “apoptosis–necrosis continuum” which is the relationship between these two processes, is disrupted. © 2018, The Author(s).},

note = {16},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-85040594067,

title = {The ultrastructure of the hepatic cells in millipedes (Myriapoda, Diplopoda)},

author = { M.M. Rost-Roszkowska and J. Vilimová and K. Tajovský and V. Šustr and A. Sosinka and M. Kszuk-Jendrysik and A. Ostróżka and F. Kaszuba and K. Kamińska and A. Marchewka},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85040594067&doi=10.1016%2fj.jcz.2018.01.006&partnerID=40&md5=e1a5d1c546a04e9960db4d0b7878c65b},

doi = {10.1016/j.jcz.2018.01.006},

issn = {00445231},

year  = {2018},

date = {2018-01-01},

journal = {Zoologischer Anzeiger},

volume = {274},

pages = {95-102},

publisher = {Elsevier GmbH},

abstract = {The hepatic cells are characteristic cells that occur in millipede body where they form a continuous layer which surrounds the midgut epithelium. The following species, which represent five millipede orders were selected: Julus scandinavius (Julida), Polyxenus lagurus (Polyxenida), Polydesmus angustus (Polydesmida; Polydesmidae), Strongylosoma stigmatosum (Polydesmida; Paradoxosomatidae), Epibolus pulchripes (Spirobolida; Pachybolidae), and two species of the order Spirostreptida, Archispirostreptus gigas and Telodeinopus aoutii. The hepatic cells are absent in P. lagurus in which the midgut epithelium is surrounded by the visceral muscles. In the other species they were arranged around the midgut as coherent hepatic cells of mesenchymal character. Each hepatic cell possessed its own basal lamina and formed the cellular processes which protrude into the basal lamina of the midgut to make contact with midgut digestive cells. Accumulation of reserve material in different millipede taxa has been described with the special emphasis on the process of autophagy in the cytoplasm of the hepatic cells. The lack of hepatic cells may represent an ancestral condition within millipedes. © 2018 Elsevier GmbH},

note = {2},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-85037975120,

title = {Effects of food contaminated with cadmium and copper on hemocytes of Steatoda grossa (Araneae: Theridiidae)},

author = { G. Wilczek and K. Wiśniewska and B. Kozina and P. Wilczek and M.M. Rost-Roszkowska and M. Stalmach and M. Skowronek and F. Kaszuba},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85037975120&doi=10.1016%2fj.ecoenv.2017.12.007&partnerID=40&md5=0065fdd37db8fba7fb6784c5cf29e2e3},

doi = {10.1016/j.ecoenv.2017.12.007},

issn = {01476513},

year  = {2018},

date = {2018-01-01},

journal = {Ecotoxicology and Environmental Safety},

volume = {149},

pages = {267-274},

publisher = {Academic Press},

abstract = {The aim of this study was to evaluate the metabolic condition of Steatoda grossa (Theridiidae) spider, from their hemocytes, after a short-term (four-week) exposure to cadmium and copper in sublethal doses by administering them into the body of the preys. The ultrastructure of the dominant types of hemocytes, such as granulocytes, plasmatocytes and prohemocytes, was evaluated using transmission electron microscope (TEM). Quantitative evaluation of apoptotic and necrotic cells, as well as the ones with depolarized mitochondria in hemolymph, was performed using flow cytometry, while ATP concentration and ADP/ATP ratio in hemocytes were measured by luminescent methods. Cadmium, unlike copper, demonstrated proapoptotic and pronecrotic activity. Low ATP levels and high ADP/ATP ratio in hemocytes indicate a disturbance in the energy metabolism of cells and may account for their qualitative and quantitative degenerative changes. The intensification of death processes in hemocytes after an exposure to cadmium-contaminated food may impair the ability of these cells to fight infectious diseases. Copper at the applied dosage was safe for the spiders without causing visible changes in the hemocyte ultrastructure and in the level of analyzed cell death indices. © 2017 Elsevier Inc.},

note = {12},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-85034645962,

title = {Changes in the midgut cells in the European cave spider, Meta menardi, during starvation in spring and autumn},

author = { S. Lipovšek and G. Leitinger and T. Novak and F. Janžekovič and S. Gorgoń and K. Kamińska and M.M. Rost-Roszkowska},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85034645962&doi=10.1007%2fs00418-017-1623-z&partnerID=40&md5=5fc4ae06f1b590ba36a54b7f6086a3c0},

doi = {10.1007/s00418-017-1623-z},

issn = {09486143},

year  = {2018},

date = {2018-01-01},

journal = {Histochemistry and Cell Biology},

volume = {149},

number = {3},

pages = {245-260},

publisher = {Springer Verlag},

abstract = {During the growth period, in surface habitats, spiders catch enough prey to feed normally. In contrast, in the cave entrance zone, prey may be relatively scarce. Meta menardi inhabits this cave section, resulting in temporary starvation. We studied structural changes in the midgut epithelial cells of M. menardi during a short-term and a medium-term controlled starvation to mimic the occasional starvation in caves, during spring and autumn. Digestive cells, secretory cells and adipocytes were examined before the experimental starvation, in the middle and at the end of starvation. We used light microscopy, transmission electron microscopy and specific histochemical methods for the detection of lipids, polysaccharides and proteins. Detection of lysosomes, autolysosomes and apoptosis was also carried out. The general structures of the cells did not change during the experimental starvation in either season, while some specific differences in the ultrastructure were observed. In both sexes, in both seasons, the amounts of lipids, glycogen and proteins decreased during starvation. Larger amounts of lipids were found in autumn, while there were no significant differences in the amounts of glycogen and proteins. In both sexes, in both seasons, autophagy and apoptosis intensified with starvation in progress, but more intensively in females. Thus, autumn individuals, in contrast to spring ones, compile energy-supplying stores to confront the subsequent winter deficiency of prey in caves, while the cellular ultrastructures undergo the same starvation-dependant changes at any time during the growth period. © 2017, Springer-Verlag GmbH Germany, part of Springer Nature.},

note = {18},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-85020752319,

title = {Fine structure of the midgut epithelium in the millipede Telodeinopus aoutii (Myriapoda, Diplopoda) with special emphasis on epithelial regeneration},

author = { M.M. Rost-Roszkowska and M. Kszuk-Jendrysik and A. Marchewka and I. Poprawa},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85020752319&doi=10.1007%2fs00709-017-1131-y&partnerID=40&md5=a3781f2c8cd62a43c01405cb2d7fa4b6},

doi = {10.1007/s00709-017-1131-y},

issn = {0033183X},

year  = {2018},

date = {2018-01-01},

journal = {Protoplasma},

volume = {255},

number = {1},

pages = {43-55},

publisher = {Springer-Verlag Wien},

abstract = {The midgut of millipedes is composed of a simple epithelium that rests on a basal lamina, which is surrounded by visceral muscles and hepatic cells. As the material for our studies, we chose Telodeinopus aoutii (Demange; 1971) (Kenyan millipede) (Diplopoda; Spirostreptida), which lives in the rain forests of Central Africa. This commonly reared species is easy to obtain from local breeders and easy to culture in the laboratory. During our studies, we used transmission and scanning electron microscopes and light and fluorescent microscopes. The midgut epithelium of the species examined here shares similarities to the structure of the millipedes analyzed to date. The midgut epithelium is composed of three types of cells—digestive, secretory, and regenerative cells. Evidence of three types of secretion have been observed in the midgut epithelium: merocrine, apocrine, and microapocrine secretion. The regenerative cells of the midgut epithelium in millipedes fulfill the role of midgut stem cells because of their main functions: self-renewal (the ability to divide mitotically and to maintain in an undifferentiated state) and potency (ability to differentiate into digestive cells). We also confirmed that spot desmosomes are common intercellular junctions between the regenerative and digestive cells in millipedes. © 2017, Springer-Verlag Wien.},

note = {7},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-85008512145,

title = {Ultrastructure of the midgut in Heteroptera (Hemiptera) with different feeding habits},

author = { H.P. Santos and M.M. Rost-Roszkowska and J. Vilimová and J.E. Serrão},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85008512145&doi=10.1007%2fs00709-016-1051-2&partnerID=40&md5=611dbc357a2a12b95a88343e7e1c2252},

doi = {10.1007/s00709-016-1051-2},

issn = {0033183X},

year  = {2017},

date = {2017-01-01},

journal = {Protoplasma},

volume = {254},

number = {4},

pages = {1743-1753},

publisher = {Springer-Verlag Wien},

abstract = {Heteroptera have diverse feeding habits with phytophagous, zoophagous, and haematophagous species. This dietary diversity associated with the monophyly of Heteroptera makes these insects a good object for comparative studies of the digestive tract. This work compares the ultrastructure of the middle midgut region in the phytophagous Coptosoma scutellatum (Plataspidae), Graphosoma lineatum (Pentatomidae), Kleidocerys resedae (Lygaeidae), and zoophagous Rhynocoris iracundus (Reduviidae), Nabis rugosus (Nabidae), and Himacerus apterus (Nabidae), to verify if diet affects midgut cells in phylogenetically related insects. The middle region of the midgut was used for comparison because it is the main site for digestion and absorption of the midgut. The digestive cell ultrastructure was similar in the six species, with features of secretory, absorptive, transport, storage, and excretory cells, suggesting a stronger correlation of middle digestive cell ultrastructure with the phylogeny of these species than with the different heteropteran feeding habits. © 2017, Springer-Verlag Wien.},

note = {17},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-85015287243,

title = {The effect of starvation and re-feeding on mitochondrial potential in the midgut of Neocaridina davidi (Crustacea, Malacostraca)},

author = { A. Włodarczyk and L. Sonakowska and K. Kamińska and A. Marchewka and G. Wilczek and P. Wilczek and S. Student and M.M. Rost-Roszkowska},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85015287243&doi=10.1371%2fjournal.pone.0173563&partnerID=40&md5=2515bc379b7fb722c49bbc72ba10f29e},

doi = {10.1371/journal.pone.0173563},

issn = {19326203},

year  = {2017},

date = {2017-01-01},

journal = {PLoS ONE},

volume = {12},

number = {3},

publisher = {Public Library of Science},

abstract = {The midgut in the freshwater shrimp Neocaridina davidi (previously named N. heteropoda) (Crustacea; Malacostraca) is composed of a tube-shaped intestine and a large hepatopancreas that is formed by numerous blind-ended tubules. The precise structure and ultrastructure of these regions were presented in our previous papers, while here we focused on the ultrastructural changes that occurred in the midgut epithelial cells (D-cells in the intestine; Band F- cells in the hepatopancreas) after long-term starvation and re-feeding. We used transmission electron microscopy, light and confocal microscopes and flow cytometry to describe all of the changes that occurred due to the stressor with special emphasis on mitochondrial alterations. A quantitative assessment of cells with depolarized mitochondria helped us to establish whether there is a relationship between starvation, re-feeding and the inactivation/activation of mitochondria. The results of our studies showed that in the freshwater shrimp N. davidi that were analyzed, long-term starvation activates the degeneration of epithelial cells at the ultrastructural level and causes an increase of cells with depolarized (non-active) mitochondria. The process of re-feeding leads to the gradual regeneration of the cytoplasm of the midgut epithelial cells; however, these changes were observed at the ultrastructural level. Additionally, re-feeding causes the regeneration of mitochondrial ultrastructure. Therefore, we can state that the increase in the number of cells with polarized mitochondria occurs slowly and does not depend on ultrastructural alterations. © 2017 Włodarczyk et al.This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.},

note = {17},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-85010006578,

title = {Investigation of the midgut structure and ultrastructure in Cimex lectularius and Cimex pipistrelli (Hemiptera: Cimicidae)},

author = { M.M. Rost-Roszkowska and J. Vilimová and A. Włodarczyk and L. Sonakowska and K. Kamińska and F. Kaszuba and A. Marchewka and D. Sadílek},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85010006578&doi=10.1007%2fs13744-016-0430-x&partnerID=40&md5=439129b41c6b9d2da771bbf898953f73},

doi = {10.1007/s13744-016-0430-x},

issn = {1519566X},

year  = {2017},

date = {2017-01-01},

journal = {Neotropical Entomology},

volume = {46},

number = {1},

pages = {45-57},

publisher = {Springer New York LLC},

abstract = {Cimicidae are temporary ectoparasites, which means that they cannot obtain food continuously. Both Cimex species examined here, Cimex lectularius (Linnaeus 1758) and Cimex pipistrelli (Jenyns 1839), can feed on a non-natal host, C. lectularius from humans on bats, C. pipistrelli on humans, but never naturally. The midgut of C. lectularius and C. pipistrelli is composed of three distinct regions—the anterior midgut (AMG), which has a sack-like shape, the long tube-shaped middle midgut (MMG), and the posterior midgut (PMG). The different ultrastructures of the AMG, MMG, and PMG in both of the species examined suggest that these regions must fulfill different functions in the digestive system. Ultrastructural analysis showed that the AMG fulfills the role of storing food and synthesizing and secreting enzymes, while the MMG is the main organ for the synthesis of enzymes, secretion, and the storage of the reserve material. Additionally, both regions, the AMG and MMG, are involved in water absorption in the digestive system of both Cimex species. The PMG is the part of the midgut in which spherites accumulate. The results of our studies confirm the suggestion of former authors that the structure of the digestive tract of insects is not attributed solely to diet but to the basic adaptation of an ancestor. © 2016, The Author(s).},

note = {5},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-85009157214,

title = {Short-term in vivo exposure to graphene oxide can cause damage to the gut and testis},

author = { M. Dziewięcka and J. Karpeta-Kaczmarek and M. Augustyniak and M.M. Rost-Roszkowska},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85009157214&doi=10.1016%2fj.jhazmat.2017.01.012&partnerID=40&md5=ca2682854bc1a00b81f9cfc494e9ce7b},

doi = {10.1016/j.jhazmat.2017.01.012},

issn = {03043894},

year  = {2017},

date = {2017-01-01},

journal = {Journal of Hazardous Materials},

volume = {328},

pages = {80-89},

publisher = {Elsevier B.V.},

abstract = {Graphene oxide (GO) has unique physicochemical properties and also has a potentially widespread use in every field of daily life (industry; science; medicine). Demand for nanotechnology is growing every year, and therefore many aspects of its toxicity and biocompatibility still require further clarification. This research assesses the in vivo toxicity of pure and manganese ion-contaminated GO that were administrated to Acheta domesticus with food (at 200 mg kg−1of food) throughout their ten-day adult life. Our results showed that short-term exposure to graphene oxide in food causes an increase in the parameters of oxidative stress of the tested insects (catalase – CAT; total antioxidant capacity – TAC), induces damage to the DNA at a level of approximately 35% and contributes to a disturbance in the stages of the cell cycle and causes an increase of apoptosis. Moreover, upon analyzing histological specimens, we found numerous degenerative changes in the cells of the gut and testis of Acheta domesticus as early as ten days after applying GO. A more complete picture of the GO risk can help to define its future applications and methods for working with the material, which may help us to avoid any adverse effects and damage to the animal. © 2017 Elsevier B.V.},

note = {25},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-85013763791,

title = {Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)},

author = { I. Poprawa and M.M. Rost-Roszkowska and D.J. Klionsky and K. Abdelmohsen and A. Abe and M.J. Abedin and H. Abeliovich and A. Acevedo-Arozena and H. Adachi and C.M. Adams and P.D. Adams and K. Adeli and P.J. Adhihetty and S.G. Adler and G. Agam and R. Agarwal and M.K. Aghi and M. Agnello and P. Agostinis and P.V. Aguilar and J.A. Aguirre-Ghiso and E.M. Airoldi and S. Ait-Si-Ali and T. Akematsu and E.T. Akporiaye and M. Al-Rubeai and G.M. Albaiceta and C. Albanese and D. Albani and M.L. Albert and J. Aldudo and H. Algül and M. Alirezaei and I. Alloza and A. Almasan and M. Almonte-Beceril and E.S. Alnemri and C. Alonso and N. Altan-Bonnet and D.C. Altieri and S. Alvarez and L. Alvarez-Erviti and S. Alves and G. Amadoro and A. Amano and C. Amantini and S. Ambrosio and I. Amelio and A.O. Amer and M. Amessou and A. Amon and Z. An and Authors. Other},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85013763791&doi=10.1080%2f15548627.2015.1100356&partnerID=40&md5=c7b9c89e5113f0c72d642ba75e5097c9},

doi = {10.1080/15548627.2015.1100356},

issn = {15548627},

year  = {2016},

date = {2016-01-01},

journal = {Autophagy},

volume = {12},

number = {1},

pages = {1-222},

publisher = {Taylor and Francis Inc.},

abstract = {[No abstract available] 

Authors: Klionsky, D.J.; Abdelmohsen, K.; Abe, A.; Abedin, M.J.; Abeliovich, H.; Acevedo-Arozena, A.; Adachi, H.; Adams, C.M.; Adams, P.D.; Adeli, K.; Adhihetty, P.J.; Adler, S.G.; Agam, G.; Agarwal, R.; Aghi, M.K.; Agnello, M.; Agostinis, P.; Aguilar, P.V.; Aguirre-Ghiso, J.A.; Airoldi, E.M.; Ait-Si-Ali, S.; Akematsu, T.; Akporiaye, E.T.; Al-Rubeai, M.; Albaiceta, G.M.; Albanese, C.; Albani, D.; Albert, M.L.; Aldudo, J.; Algül, H.; Alirezaei, M.; Alloza, I.; Almasan, A.; Almonte-Beceril, M.; Alnemri, E.S.; Alonso, C.; Altan-Bonnet, N.; Altieri, D.C.; Alvarez, S.; Alvarez-Erviti, L.; Alves, S.; Amadoro, G.; Amano, A.; Amantini, C.; Ambrosio, S.; Amelio, I.; Amer, A.O.; Amessou, M.; Amon, A.; An, Z.; Anania, F.A.; Andersen, S.U.; Andley, U.P.; Andreadi, C.K.; Andrieu-Abadie, N.; Anel, A.; Ann, D.K.; Anoopkumar-Dukie, S.; Antonioli, M.; Aoki, H.; Apostolova, N.; Aquila, S.; Aquilano, K.; Araki, K.; Arama, E.; Aranda, A.; Araya, J.; Arcaro, A.; Arias, E.; Arimoto, H.; Ariosa, A.R.; Armstrong, J.L.; Arnould, T.; Arsov, I.; Asanuma, K.; Askanas, V.; Asselin, E.; Atarashi, R.; Atherton, S.S.; Atkin, J.D.; Attardi, L.D.; Auberger, P.; Auburger, G.; Aurelian, L.; Autelli, R.; Avagliano, L.; Avantaggiati, M.L.; Avrahami, L.; Azad, N.; Awale, S.; Bachetti, T.; Backer, J.M.; Bae, D.H.; Bae, J.S.; Bae, O.N.; Bae, S.H.; Baehrecke, E.H.; Baek, S.H.; Baghdiguian, S.; Bagniewska-Zadworna, A.; Bai, H.; Bai, J.; Bai, X.Y.; Bailly, Y.; Balaji, K.N.; Balduini, W.; Ballabio, A.; Balzan, R.; Banerjee, R.; Bánhegyi, G.; Bao, H.; Barbeau, B.; Barrachina, M.D.; Barreiro, E.; Bartel, B.; Bartolomé, A.; Bassham, D.C.; Bassi, M.T.; Bast Jr. R.C.; Basu, A.; Batista, M.T.; Batoko, H.; Battino, M.; Bauckman, K.; Baumgarner, B.L.; Bayer, K.U.; Beale, R.; Beaulieu, J.F.; Beck, G.R.; Becker, C.; Beckham, J.D.; Bédard, P.A.; Bednarski, P.J.; Begley, T.J.; Behl, C.; Behrends, C.; Behrens, G.M.N.; Behrns, K.E.; Bejarano, E.; Belaid, A.; Belleudi, F.; Bénard, G.; Berchem, G.; Bergamaschi, D.; Bergami, M.; Berkhout, B.; Berliocchi, L.; Bernard, A.; Bernard, M.; Bernassola, F.; Bertolotti, A.; Bess, A.S.; Besteiro, S.; Bettuzzi, S.; Bhalla, S.; Bhattacharyya, S.; Bhutia, S.K.; Biagosch, C.; Bianchi, M.W.; Biard-Piechaczyk, M.; Billes, V.; Bincoletto, C.; Bingol, B.; Bird, S.W.; Bitoun, M.; Bjedov, I.; Blackstone, C.; Blanc, L.; Blanco, G.A.; Blomhoff, H.K.; Boada-Romero, E.; Böckler, S.; Boes, M.; Boesze-Battaglia, K.; Boise, L.H.; Bolino, A.; Boman, A.; Bonaldo, P.; Bordi, M.; Bosch, J.; Botana, L.M.; Botti, J.; Bou, G.; Bouché, M.; Bouchecareilh, M.; Boucher, M.J.; Boulton, M.E.; Bouret, S.G.; Boya, P.; Boyer-Guittaut, M.; Bozhkov, P.V.; Brady, N.R.; Braga, V.M.M.; Brancolini, C.; Braus, G.H.; Bravo-San-Pedro, J.M.; Brennan, L.A.; Bresnick, E.H.; Brest, P.; Bridges, D.; Bringer, M.A.; Brini, M.; Brito, G.C.; Brodin, B.; Brookes, P.S.; Brown, E.J.; Brown, K.; Broxmeyer, H.E.; Bruhat, A.; Brum, P.C.; Brumell, J.H.; Brunetti-Pierri, N.; Bryson-Richardson, R.J.; Buch, S.; Buchan, A.M.; Budak, H.; Bulavin, D.V.; Bultman, S.J.; Bultynck, G.; Bumbasirevic, V.; Burelle, Y.; Burke, R.E.; Burmeister, M.; Bütikofer, P.; Caberlotto, L.; Cadwell, K.; Cahová, M.; Cai, D.; Cai, J.; Cai, Q.; Calatayud, S.; Camougrand, N.; Campanella, M.; Campbell, G.R.; Campbell, M.; Campello, S.; Candau, R.; Caniggia, I.; Cantoni, L.; Cao, L.; Caplan, A.B.; Caraglia, M.; Cardinali, C.; Cardoso, S.M.; Carew, J.S.; Carleton, L.A.; Carlin, C.R.; Carloni, S.; Carlsson, S.R.; Carmona-Gutierrez, D.; Carneiro, L.A.M.; Carnevali, O.; Carra, S.; Carrier, A.; Carroll, B.; Casas, C.; Casas, J.; Cassinelli, G.; Castets, P.; Castro-Obregon, S.; Cavallini, G.; Ceccherini, I.; Cecconi, F.; Cederbaum, A.I.; Ceña, V.; Cenci, S.; Cerella, C.; Cervia, D.; Cetrullo, S.; Chaachouay, H.; Chae, H.J.; Chagin, A.S.; Chai, C.Y.; Chakrabarti, G.; Chamilos, G.; Chan, E.Y.W.; Chan, M.T.V.; Chandra, D.; Chandra, P.; Chang, C.P.; Chang, R.C.C.; Chang, T.Y.; Chatham, J.C.; Chatterjee, S.; Chauhan, S.; Che, Y.; Cheetham, M.E.; Cheluvappa, R.; Chen, C.J.; Chen, G.; Chen, G.C.; Chen, G.Q.; Chen, H.; Chen, J.W.; Chen, J.K.; Chen, M.; Chen, M.; Chen, P.; Chen, Q.; Chen, Q.; Chen, S.D.; Chen, S.; Chen, S.S.L.; Chen, W.; Chen, W.J.; Chen, W.Q.; Chen, W.; Chen, X.; Chen, Y.H.; Chen, Y.G.; Chen, Y.; Chen, Y.; Chen, Y.; Chen, Y.J.; Chen, Y.Q.; Chen, Y.; Chen, Z.; Chen, Z.; Cheng, A.; Cheng, C.H.K.; Cheng, H.; Cheong, H.; Cherry, S.; Chesney, J.; Cheung, C.H.A.; Chevet, E.; Chi, H.C.; Chi, S.G.; Chiacchiera, F.; Chiang, H.L.; Chiarelli, R.; Chiariello, M.; Chieppa, M.; Chin, L.S.; Chiong, M.; Chiu, G.N.C.; Cho, D.H.; Cho, S.G.; Cho, W.C.; Cho, Y.Y.; Cho, Y.S.; Choi, A.M.K.; Choi, E.J.; Choi, E.K.; Choi, J.; Choi, M.E.; Choi, S.I.; Chou, T.F.; Chouaib, S.; Choubey, D.; Choubey, V.; Chow, K.C.; Chowdhury, K.; Chu, C.T.; Chuang, T.H.; Chun, T.; Chung, H.; Chung, T.; Chung, Y.L.; Chwae, Y.J.; Cianfanelli, V.; Ciarcia, R.; Ciechomska, I.A.; Ciriolo, M.R.; Cirone, M.; Claerhout, S.; Clague, M.J.; Clària, J.; Clarke, P.G.H.; Clarke, R.; Clementi, E.; Cleyrat, C.; Cnop, M.; Coccia, E.M.; Cocco, T.; Codogno, P.; Coers, J.; Cohen, E.E.W.; Colecchia, D.; Coletto, L.; Coll, N.S.; Colucci-Guyon, E.; Comincini, S.; Condello, M.; Cook, K.L.; Coombs, G.H.; Cooper, C.D.; Cooper, J.M.; Coppens, I.; Corasaniti, M.T.; Corazzari, M.; Corbalan, R.; Corcelle-Termeau, E.; Cordero, M.D.; Corral-Ramos, C.; Corti, O.; Cossarizza, A.; Costelli, P.; Costes, S.; Cotman, S.L.; Coto-Montes, A.; Cottet, S.; Couve, E.; Covey, L.R.; Cowart, L.A.; Cox, J.S.; Coxon, F.P.; Coyne, C.B.; Cragg, M.S.; Craven, R.J.; Crepaldi, T.; Crespo, J.L.; Criollo, A.; Crippa, V.; Cruz, M.T.; Cuervo, A.M.; Cuezva, J.M.; Cui, T.; Cutillas, P.R.; Czaja, M.J.; Czyzyk-Krzeska, M.F.; Dagda, R.K.; Dahmen, U.; Dai, C.; Dai, W.; Dai, Y.; Dalby, K.N.; Valle, L.D.; Dalmasso, G.; D'amelio, M.; Damme, M.; Darfeuille-Michaud, A.; Dargemont, C.; Darley-Usmar, V.M.; Dasarathy, S.; Dasgupta, B.; Dash, S.; Dass, C.R.; Davey, H.M.; Davids, L.M.; Dávila, D.; Davis, R.J.; Dawson, T.M.; Dawson, V.L.; Daza, P.; de Belleroche, J.; de Figueiredo, P.; de Figueiredo, R.C.B.Q.; de la Fuente, J.; De Martino, L.; De Matteis, A.; De Meyer, G.R.Y.; De Milito, A.; De Santi, M.; de Souza, W.; De Tata, V.; De Zio, D.; Debnath, J.; Dechant, R.; Decuypere, J.P.; Deegan, S.; Dehay, B.; Del Bello, B.; Del Re, D.P.; Delage-Mourroux, R.; Delbridge, L.M.D.; Deldicque, L.; Delorme-Axford, E.; Deng, Y.Z.; Dengjel, J.; Denizot, M.; Dent, P.; Der, C.J.; Deretic, V.; Derrien, B.; Deutsch, E.; Devarenne, T.P.; Devenish, R.J.; Di Bartolomeo, S.; Di Daniele, N.; Di Domenico, F.; Di Nardo, A.; Di Paola, S.; Di Pietro, A.; Di Renzo, L.; Di Antonio, A.; Díaz-Araya, G.; Díaz-Laviada, I.; Diaz-Meco, M.T.; Diaz-Nido, J.; Dickey, C.A.; Dickson, R.C.; Diederich, M.; Digard, P.; Dikic, I.; Dinesh-Kumar, S.P.; Ding, C.; Ding, W.X.; Ding, Z.; Dini, L.; Distler, J.H.W.; Diwan, A.; Djavaheri-Mergny, M.; Dmytruk, K.; Dobson, R.C.J.; Doetsch, V.; Dokladny, K.; Dokudovskaya, S.; Donadelli, M.; Dong, X.C.; Dong, X.; Dong, Z.; Donohue, T.M.; Donohue-Jr, T.M.; Doran, K.S.; D'orazi, G.; Dorn, G.W.; Dosenko, V.; Dridi, S.; Drucker, L.; Du, J.; Du, L.L.; Du, L.; du Toit, A.; Dua, P.; Duan, L.; Duann, P.; Dubey, V.K.; Duchen, M.R.; Duchosal, M.A.; Duez, H.; Dugail, I.; Dumit, V.I.; Duncan, M.C.; Dunlop, E.A.; Dunn, W.A.; Dupont, N.; Dupuis, L.; Durán, R.V.; Durcan, T.M.; Duvezin-Caubet, S.; Duvvuri, U.; Eapen, V.; Ebrahimi-Fakhari, D.; Echard, A.; Eckhart, L.; Edelstein, C.L.; Edinger, A.L.; Eichinger, L.; Eisenberg, T.; Eisenberg-Lerner, A.; Eissa, N.T.; El-Deiry, W.S.; El-Khoury, V.; Elazar, Z.; Eldar-Finkelman, H.; Elliott, C.J.H.; Emanuele, E.; Emmenegger, U.; Engedal, N.; Engelbrecht, A.M.; Engelender, S.; Enserink, J.M.; Erdmann, R.; Erenpreisa, J.; Eri, R.; Eriksen, J.L.; Erman, A.; Escalante, R.; Eskelinen, E.L.; Espert, L.; Esteban-Martínez, L.; Evans, T.J.; Fabri, M.; Fabrias, G.; Fabrizi, C.; Facchiano, A.; Færgeman, N.J.; Faggioni, A.; Fairlie, W.D.; Fan, C.; Fan, D.; Fan, J.; Fang, S.; Fanto, M.; Fanzani, A.; Farkas, T.; Faure, M.; Favier, F.B.; Fearnhead, H.; Federici, M.; Fei, E.; Felizardo, T.C.; Feng, H.; Feng, Y.; Feng, Y.; Ferguson, T.A.; Fernández, Á.F.; Fernandez-Barrena, M.G.; Fernandez-Checa, J.C.; Fernández-López, A.; Fernandez-Zapico, M.E.; Feron, O.; Ferraro, E.; Ferreira-Halder, C.V.; Fésüs, L.; Feuer, R.; Fiesel, F.C.; Filippi-Chiela, E.C.; Filomeni, G.; Fimia, G.M.; Fingert, J.H.; Finkbeiner, S.; Finkel, T.; Fiorito, F.; Fisher, P.B.; Flajolet, M.; Flamigni, F.; Florey, O.; Florio, S.; Floto, R.A.; Folini, M.; Follo, C.; Fon, E.A.; Fornai, F.; Fortunato, F.; Fraldi, A.; Franco, R.; Francois, A.; François, A.; Frankel, L.B.; Fraser, I.D.C.; Frey, N.; Freyssenet, D.G.; Frezza, C.; Friedman, S.L.; Frigo, D.E.; Fu, D.; Fuentes, J.M.; Fueyo, J.; Fujitani, Y.; Fujiwara, Y.; Fujiya, M.; Fukuda, M.; Fulda, S.; Fusco, C.; Gabryel, B.; Gaestel, M.; Gailly, P.; Gajewska, M.; Galadari, S.; Galili, G.; Galindo, I.; Galindo, M.F.; Galliciotti, G.; Galluzzi, L.; Galluzzi, L.; Galy, V.; Gammoh, N.; Gandy, S.; Ganesan, A.K.; Ganesan, S.; Ganley, I.G.; Gannagé, M.; Gao, F.B.; Gao, F.; Gao, J.X.; Nannig, L.G.; Véscovi, E.G.; Garcia-Macía, M.; Garcia-Ruiz, C.; Garg, A.D.; Garg, P.K.; Gargini, R.; Gassen, N.C.; Gatica, D.; Gatti, E.; Gavard, J.; Gavathiotis, E.; Ge, L.; Ge, P.; Ge, S.; Gean, P.W.; Gelmetti, V.; Genazzani, A.A.; Geng, J.; Genschik, P.; Gerner, L.; Gestwicki, J.E.; Gewirtz, D.A.; Ghavami, S.; Ghigo, E.; Ghosh, D.; Giammarioli, A.M.; Giampieri, F.; Giampietri, C.; Giatromanolaki, A.N.; Gibbings, D.J.; Gibellini, L.; Gibson, S.B.; Ginet, V.; Giordano, A.; Giorgini, F.; Giovannetti, E.; Girardin, S.E.; Gispert, S.; Giuliano, S.; Gladson, C.L.; Glavic, A.; Gleave, M.; Godefroy, N.; Gogal, R.M.; Gokulan, K.; Goldman, G.H.; Goletti, D.; Goligorsky, M.S.; Gomes, A.V.; Gomes, L.C.; Gomez, H.; Gomez-Manzano, C.; Gómez-Sánchez, R.; Gonçalves, D.A.P.; Goncu, E.; Gong, Q.; Gongora, C.; Gonzalez, C.B.; Gonzalez-Alegre, P.; Gonzalez-Cabo, P.; González-Polo, R.A.; Goping, I.S.; Gorbea, C.; Gorbunov, N.V.; Goring, D.R.; Gorman, A.M.; Gorski, S.M.; Goruppi, S.; Goto-Yamada, S.; Gotor, C.; Gottlieb, R.A.; Gozes, I.; Gozuacik, D.; Graba, Y.; Graef, M.; Granato, G.E.; Grant, G.D.; Grant, S.; Gravina, G.L.; Green, D.R.; Greenhough, A.; Greenwood, M.T.; Grimaldi, B.; Gros, F.; Grose, C.; Groulx, J.F.; Gruber, F.; Grumati, P.; Grune, T.; Guan, J.L.; Guan, K.L.; Guerra, B.; Guillen, C.; Gulshan, K.; Gunst, J.; Guo, C.; Guo, L.; Guo, M.; Guo, W.; Guo, X.G.; Gust, A.A.; Gustafsson, Å.B.; Gutierrez, E.; Gutierrez, M.G.; Gwak, H.S.; Haas, A.; Haber, J.E.; Hadano, S.; Hagedorn, M.; Hahn, D.R.; Halayko, A.J.; Hamacher-Brady, A.; Hamada, K.; Hamai, A.; Hamann, A.; Hamasaki, M.; Hamer, I.; Hamid, Q.; Hammond, E.M.; Han, F.; Han, W.; Handa, J.T.; Hanover, J.A.; Hansen, M.; Harada, M.; Harhaji-Trajkovic, L.; Harper, J.W.; Harrath, A.H.; Harris, A.L.; Harris, J.; Hasler, U.; Hasselblatt, P.; Hasui, K.; Hawley, R.G.; Hawley, T.S.; He, C.; He, C.Y.; He, F.; He, G.; He, R.R.; He, X.H.; He, Y.W.; He, Y.Y.; Heath, J.K.; Hébert, M.J.; Heinzen, R.A.; Helgason, G.V.; Hensel, M.; Henske, E.P.; Her, C.; Herman, P.K.; Hernández, A.; Hernandez, C.; Hernández-Tiedra, S.; Hetz, C.; Hiesinger, P.R.; Higaki, K.; Hilfiker, S.; Hill, B.G.; Hill, J.A.; Hill, W.D.; Hino, K.; Hofius, D.; Hofman, P.; Höglinger, G.U.; Höhfeld, J.; Holz, M.K.; Hong, Y.; Hood, D.A.; Hoozemans, J.J.M.; Hoppe, T.; Hsu, C.; Hsu, C.Y.; Hsu, L.C.; Hu, D.; Hu, G.; Hu, H.M.; Hu, H.; Hu, M.C.; Hu, Y.C.; Hu, Z.W.; Hua, F.; Hua, Y.; Huang, C.; Huang, H.L.; Huang, K.H.; Huang, K.Y.; Huang, S.; Huang, S.; Huang, W.P.; Huang, Y.R.; Huang, Y.; Huang, Y.; Huber, T.B.; Huebbe, P.; Huh, W.K.; Hulmi, J.J.; Hur, G.M.; Hurley, J.H.; Husak, Z.; Hussain, S.N.A.; Hussain, S.; Hwang, J.J.; Hwang, S.; Hwang, T.I.S.; Ichihara, A.; Imai, Y.; Imbriano, C.; Inomata, M.; Into, T.; Iovane, V.; Iovanna, J.L.; Iozzo, R.V.; Ip, N.Y.; Irazoqui, J.E.; Iribarren, P.; Isaka, Y.; Isakovic, A.J.; Ischiropoulos, H.; Isenberg, J.S.; Ishaq, M.; Ishida, H.; Ishii, I.; Ishmael, J.E.; Isidoro, C.; Isobe, K.I.; Isono, E.; Issazadeh-Navikas, S.; Itahana, K.; Itakura, E.; Ivanov, A.I.; Iyer, A.K.V.; Izquierdo, J.M.; Izumi, Y.; Izzo, V.; Jäättelä, M.; Jaber, N.; Jackson, D.J.; Jackson, W.T.; Jacob, T.G.; Jacques, T.S.; Jagannath, C.; Jain, A.; Jana, N.R.; Jang, B.K.; Jani, A.; Janji, B.; Jannig, P.R.; Jansson, P.J.; Jean, S.; Jendrach, M.; Jeon, J.H.; Jessen, N.; Jeung, E.B.; Jia, K.; Jia, L.; Jiang, H.; Jiang, H.; Jiang, L.; Jiang, T.; Jiang, X.; Jiang, X.; Jiang, Y.; Jiang, Y.; Jiménez, A.; Jin, C.; Jin, H.; Jin, L.; Jin, M.; Jin, S.; Jinwal, U.K.; Jo, E.K.; Johansen, T.; Johnson, D.E.; Johnson, G.V.W.; Johnson, J.D.; Jonasch, E.; Jones, C.; Joosten, L.A.B.; Jordan, J.; Joseph, A.M.; Joseph, B.; Joubert, A.M.; Ju, D.; Ju, J.; Juan, H.F.; Juenemann, K.; Juhász, G.; Jung, H.S.; Jung, J.U.; Jung, Y.K.; Jungbluth, H.; Justice, M.J.; Jutten, B.; Kaakoush, N.O.; Kaarniranta, K.; Kaasik, A.; Kabuta, T.; Kaeffer, B.; Kågedal, K.; Kahana, A.; Kajimura, S.; Kakhlon, O.; Kalia, M.; Kalvakolanu, D.V.; Kamada, Y.; Kambas, K.; Kaminskyy, V.O.; Kampinga, H.H.; Kandouz, M.; Kang, C.; Kang, R.; Kang, T.C.; Kanki, T.; Kanneganti, T.D.; Kanno, H.; Kanthasamy, A.G.; Kantorow, M.; Kaparakis-Liaskos, M.; Kapuy, O.; Karantza, V.; Karim, M.R.; Karmakar, P.; Kaser, A.; Kaushik, S.; Kawula, T.; Kaynar, A.M.; Ke, P.Y.; Ke, Z.J.; Kehrl, J.H.; Keller, K.E.; Kemper, J.K.; Kenworthy, A.K.; Kepp, O.; Kern, A.; Kesari, S.; Kessel, D.; Ketteler, R.; Kettelhut, I.C.; Khambu, B.; Khan, M.M.; Khandelwal, V.K.M.; Khare, S.; Kiang, J.G.; Kiger, A.A.; Kihara, A.; Kim, A.L.; Kim, C.H.; Kim, D.R.; Kim, D.H.; Kim, E.K.; Kim, H.Y.; Kim, H.R.; Kim, J.S.; Kim, J.H.; Kim, J.C.; Kim, J.H.; Kim, K.W.; Kim, M.D.; Kim, M.M.; Kim, P.K.; Kim, S.W.; Kim, S.Y.; Kim, Y.S.; Kim, Y.; Kimchi, A.; Kimmelman, A.C.; Kimura, T.; King, J.S.; Kirkegaard, K.; Kirkin, V.; Kirshenbaum, L.A.; Kishi, S.; Kitajima, Y.; Kitamoto, K.; Kitaoka, Y.; Kitazato, K.; Kley, R.A.; Klimecki, W.T.; Klinkenberg, M.; Klucken, J.; Knævelsrud, H.; Knecht, E.; Knuppertz, L.; Ko, J.L.; Kobayashi, S.; Koch, J.C.; Koechlin-Ramonatxo, C.; Koenig, U.; Koh, Y.H.; Köhler, K.; Kohlwein, S.D.; Koike, M.; Komatsu, M.; Kominami, E.; Kong, D.; Kong, H.J.; Konstantakou, E.G.; Kopp, B.T.; Korcsmaros, T.; Korhonen, L.; Korolchuk, V.I.; Koshkina, N.V.; Kou, Y.; Koukourakis, M.I.; Koumenis, C.; Kovács, A.L.; Kovács, T.; Kovacs, W.J.; Koya, D.; Kraft, C.; Krainc, D.; Krämer, H.; Kravic-Stevovic, T.; Krek, W.; Kretz-Remy, C.; Krick, R.; Krishnamurthy, M.; Kriston-Vizi, J.; Kroemer, G.; Kruer, M.C.; Krüger, R.; Ktistakis, N.T.; Kuchitsu, K.; Kuhn, C.; Kumar, A.P.; Kumar, A.; Kumar, A.; Kumar, D.; Kumar, D.; Kumar, R.; Kumar, S.; Kundu, M.; Kung, H.J.; Kuno, A.; Kuo, S.H.; Kuret, J.; Kurz, T.; Kwok, T.; Kwon, T.K.; Kwon, Y.T.; Kyrmizi, I.; La Spada, A.R.; Lafont, F.; Lahm, T.; Lakkaraju, A.; Lam, T.; Lamark, T.; Lancel, S.; Landowski, T.H.; Lane, D.J.R.; Lane, J.D.; Lanzi, C.; Lapaquette, P.; Lapierre, L.R.; Laporte, J.; Laukkarinen, J.; Laurie, G.W.; Lavandero, S.; Lavie, L.; Lavoie, M.J.; Law, B.Y.K.; Law, H.K.W.; Law, K.B.; Layfield, R.; Lazo, P.A.; Le Cam, L.; Le Roch, K.G.; Le Stunff, H.; Leardkamolkarn, V.; Lecuit, M.; Lee, B.H.; Lee, C.H.; Lee, E.F.; Lee, G.M.; Lee, H.J.; Lee, H.; Lee, J.; Lee, J.; Lee, J.H.; Lee, J.; Lee, M.; Lee, M.S.; Lee, P.J.; Lee, S.W.; Lee, S.J.; Lee, S.J.; Lee, S.Y.; Lee, S.H.; Lee, S.S.; Lee, S.J.; Lee, S.; Lee, Y.R.; Lee, Y.J.; Lee, Y.H.; Leeuwenburgh, C.; Lefort, S.; Legouis, R.; Lei, J.; Lei, Q.Y.; Leib, D.A.; Leibowitz, G.; Lekli, I.; Lemaire, S.D.; Lemasters, J.J.; Lemberg, M.K.; Lemoine, A.; Leng, S.; Lenz, G.; Lenzi, P.; Lerman, L.O.; Barbato, D.L.; Leu, J.I.J.; Leung, H.Y.; Levine, B.; Lewis, P.A.; Lezoualch, F.; Li, C.; Li, F.; Li, F.J.; Li, J.; Li, K.; Li, L.; Li, M.; Li, Q.; Li, R.; Li, S.; Li, W.; Li, X.; Li, Y.; Lian, J.; Liang, C.; Liang, Q.; Liao, Y.; Liberal, J.; Liberski, P.P.; Lie, P.; Lieberman, A.P.; Lim, H.J.; Lim, K.L.; Lim, K.; Lima, R.T.; Lin, C.S.; Lin, C.F.; Lin, F.; Lin, F.; Lin, F.C.; Lin, K.; Lin, K.H.; Lin, P.H.; Lin, T.; Lin, W.W.; Lin, Y.S.; Lin, Y.; Linden, R.; Lindholm, D.; Lindqvist, L.M.; Lingor, P.; Linkermann, A.; Liotta, L.A.; Lipinski, M.M.; Lira, V.A.; Lisanti, M.P.; Liton, P.B.; Liu, B.; Liu, C.; Liu, C.F.; Liu, F.; Liu, H.J.; Liu, J.; Liu, J.J.; Liu, J.L.; Liu, K.; Liu, L.; Liu, L.; Liu, Q.; Liu, R.Y.; Liu, S.; Liu, S.; Liu, W.; Liu, X.D.; Liu, X.; Liu, X.H.; Liu, X.; Liu, X.; Liu, X.; Liu, Y.; Liu, Y.; Liu, Z.; Liu, Z.; Liuzzi, J.P.; Lizard, G.; Ljujic, M.; Lodhi, I.J.; Logue, S.E.; Lokeshwar, B.L.; Long, Y.C.; Lonial, S.; Loos, B.; López-Otín, C.; López-Vicario, C.; Lorente, M.; Lorenzi, P.L.; Lõrincz, P.; Los, M.; Lotze, M.T.; Lovat, P.E.; Lu, B.; Lu, B.; Lu, J.; Lu, Q.; Lu, S.M.; Lu, S.; Lu, Y.; Luciano, F.; Luckhart, S.; Lucocq, J.M.; Ludovico, P.; Lugea, A.; Lukacs, N.W.; Lum, J.J.; Lund, A.H.; Luo, H.; Luo, J.; Luo, S.; Luparello, C.; Lyons, T.; Ma, J.; Ma, Y.; Ma, Y.; Ma, Z.; Machado, J.; Machado-Santelli, G.M.; Macian, F.; MacIntosh, G.C.; MacKeigan, J.P.; Macleod, K.F.; MacMicking, J.D.; MacMillan-Crow, L.A.; Madeo, F.; Madesh, M.; Madrigal-Matute, J.; Maeda, A.; Maeda, T.; Maegawa, G.; Maellaro, E.; Maes, H.; Magariños, M.; Maiese, K.; Maiti, T.K.; Maiuri, L.; Maiuri, M.C.; Maki, C.G.; Malli, R.; Malorni, W.; Maloyan, A.; Mami-Chouaib, F.; Man, N.; Mancias, J.D.; Mandelkow, E.M.; Mandell, M.A.; Manfredi, A.A.; Manié, S.N.; Manzoni, C.; Mao, K.; Mao, Z.; Mao, Z.W.; Marambaud, P.; Marconi, A.M.; Marelja, Z.; Marfe, G.; Margeta, M.; Margittai, E.; Mari, M.; Mariani, F.V.; Marin, C.; Marinelli, S.; Mariño, G.; Markovic, I.; Marquez, R.; Martelli, A.M.; Martens, S.; Martin, K.R.; Martin, S.J.; Martin, S.; Martin-Acebes, M.A.; Martín-Sanz, P.; Martinand-Mari, C.; Martinet, W.; Martinez, J.; Martinez-Lopez, N.; Martinez-Outschoorn, U.; Martínez-Velázquez, M.; Martinez-Vicente, M.; Martins, W.K.; Mashima, H.; Mastrianni, J.A.; Matarese, G.; Matarrese, P.; Mateo, R.; Matoba, S.; Matsumoto, N.; Matsushita, T.; Matsuura, A.; Matsuzawa, T.; Mattson, M.P.; Matus, S.; Maugeri, N.; Mauvezin, C.; Mayer, A.; Maysinger, D.; Mazzolini, G.D.; McBrayer, M.K.; McCall, K.; McCormick, C.; McInerney, G.M.; McIver, S.C.; McKenna, S.L.; McMahon, J.J.; McNeish, I.A.; Mechta-Grigoriou, F.; Medema, J.P.; Medina, D.L.; Megyeri, K.; Mehrpour, M.; Mehta, J.L.; Mei, Y.; Meier, U.C.; Meijer, A.J.; Meléndez, A.; Melino, G.; Melino, S.; de Melo, E.J.T.; Mena, M.A.; Meneghini, M.D.; Menendez, J.A.; Menezes, R.; Meng, L.; Meng, L.H.; Meng, S.; Menghini, R.; Menko, A.S.; Menna-Barreto, R.F.S.; Menon, M.B.; Meraz-Ríos, M.A.; Merla, G.; Merlini, L.; Merlot, A.M.; Meryk, A.; Meschini, S.; Meyer, J.N.; Mi, M.T.; Miao, C.Y.; Micale, L.; Michaeli, S.; Michiels, C.; Migliaccio, A.R.; Mihailidou, A.S.; Mijaljica, D.; Mikoshiba, K.; Milan, E.; Miller-Fleming, L.; Mills, G.B.; Mills, I.G.; Minakaki, G.; Minassian, B.A.; Ming, X.F.; Minibayeva, F.; Minina, E.A.; Mintern, J.D.; Minucci, S.; Miranda-Vizuete, A.; Mitchell, C.H.; Miyamoto, S.; Miyazawa, K.; Mizushima, N.; Mnich, K.; Mograbi, B.; Mohseni, S.; Moita, L.F.; Molinari, M.; Molinari, M.; Møller, A.B.; Mollereau, B.; Mollinedo, F.; Mongillo, M.; Monick, M.M.; Montagnaro, S.; Montell, C.; Moore, D.J.; Moore, M.N.; Mora-Rodriguez, R.; Moreira, P.I.; Morel, E.; Morelli, M.B.; Moreno, S.; Morgan, M.J.; Moris, A.; Moriyasu, Y.; Morrison, J.L.; Morrison, L.A.; Morselli, E.; Moscat, J.; Moseley, P.L.; Mostowy, S.; Motori, E.; Mottet, D.; Mottram, J.C.; Moussa, C.E.H.; Mpakou, V.E.; Mukhtar, H.; Levy, J.M.M.; Muller, S.; Muñoz-Moreno, R.; Muñoz-Pinedo, C.; Münz, C.; Murphy, M.E.; Murray, J.T.; Murthy, A.; Mysorekar, I.U.; Nabi, I.R.; Nabissi, M.; Nader, G.A.; Nagahara, Y.; Nagai, Y.; Nagata, K.; Nagelkerke, A.; Nagy, P.; Naidu, S.R.; Nair, S.; Nakano, H.; Nakatogawa, H.; Nanjundan, M.; Napolitano, G.; Naqvi, N.I.; Nardacci, R.; Narendra, D.P.; Narita, M.; Nascimbeni, A.C.; Natarajan, R.; Navegantes, L.C.; Nawrocki, S.T.; Nazarko, T.Y.; Nazarko, V.Y.; Neill, T.; Neri, L.M.; Netea, M.G.; Netea-Maier, R.T.; Neves, B.M.; Ney, P.A.; Nezis, I.P.; Nguyen, H.T.T.; Nguyen, H.P.; Nicot, A.S.; Nilsen, H.; Nilsson, P.; Nishimura, M.; Nishino, I.; Niso-Santano, M.; Niu, H.; Nixon, R.A.; Njar, V.C.O.; Noda, T.; Noegel, A.A.; Nolte, E.M.; Norberg, E.; Norga, K.K.; Noureini, S.K.; Notomi, S.; Notterpek, L.; Nowikovsky, K.; Nukina, N.; Nürnberger, T.; O'donnell, V.B.; O'donovan, T.; O'dwyer, P.J.; Oehme, I.; Oeste, C.L.; Ogawa, M.; Ogretmen, B.; Ogura, Y.; Oh, Y.J.; Ohmuraya, M.; Ohshima, T.; Ojha, R.; Okamoto, K.; Okazaki, T.; Oliver, F.J.; Ollinger, K.; Olsson, S.; Orban, D.P.; Ordonez, P.; Orhon, I.; Orosz, L.; O'rourke, E.J.; Orozco, H.; Ortega, A.L.; Ortona, E.; Osellame, L.D.; Oshima, J.; Oshima, S.; Osiewacz, H.D.; Otomo, T.; Otsu, K.; Ou, J.H.J.; Outeiro, T.F.; Ouyang, D.Y.; Ouyang, H.; Overholtzer, M.; Ozbun, M.A.; Ozdinler, P.H.; Ozpolat, B.; Pacelli, C.; Paganetti, P.; Page, G.; Pages, G.; Pagnini, U.; Pajak, B.; Pak, S.C.; Pakos-Zebrucka, K.; Pakpour, N.; Palková, Z.; Palladino, F.; Pallauf, K.; Pallet, N.; Palmieri, M.; Paludan, S.R.; Palumbo, C.; Palumbo, S.; Pampliega, O.; Pan, H.; Pan, W.; Panaretakis, T.; Pandey, A.; Pantazopoulou, A.; Papackova, Z.; Papademetrio, D.L.; Papassideri, I.; Papini, A.; Parajuli, N.; Pardo, J.; Parekh, V.V.; Parenti, G.; Park, J.I.; Park, J.; Park, O.K.; Parker, R.; Parlato, R.; Parys, J.B.; Parzych, K.R.; Pasquet, J.M.; Pasquier, B.; Pasumarthi, K.B.S.; Patterson, C.; Pattingre, S.; Pattison, S.; Pause, A.; Pavenstädt, H.; Pavone, F.; Pedrozo, Z.; Peña, F.J.; Peñalva, M.A.; Pende, M.; Peng, J.; Penna, F.; Penninger, J.M.; Pensalfini, A.; Pepe, S.; Pereira, G.J.S.; Pereira, P.C.; de la Cruz, V.P.; Pérez-Pérez, M.E.; Pérez-Rodríguez, D.; Pérez-Sala, D.; Perier, C.; Perl, A.; Perlmutter, D.H.; Perrotta, I.; Pervaiz, S.; Pesonen, M.; Pessin, J.E.; Peters, G.J.; Petersen, M.; Petrache, I.; Petrof, B.J.; Petrovski, G.; Phang, J.M.; Piacentini, M.; Pierdominici, M.; Pierre, P.; Pierrefite-Carle, V.; Pietrocola, F.; Pimentel-Muiños, F.X.; Pinar, M.; Pineda, B.; Pinkas-Kramarski, R.; Pinti, M.; Pinton, P.; Piperdi, B.; Piret, J.M.; Platanias, L.C.; Platta, H.W.; Plowey, E.D.; Pöggeler, S.; Poirot, M.; Polčic, P.; Poletti, A.; Poon, A.H.; Popelka, H.; Popova, B.; Poprawa, I.; Poulose, S.M.; Poulton, J.; Powers, S.K.; Powers, T.; Pozuelo-Rubio, M.; Prak, K.; Prange, R.; Prescott, M.; Priault, M.; Prince, S.; Proia, R.L.; Proikas-Cezanne, T.; Prokisch, H.; Promponas, V.J.; Przyklenk, K.; Puertollano, R.; Pugazhenthi, S.; Puglielli, L.; Pujol, A.; Puyal, J.; Pyeon, D.; Qi, X.; Qian, W.B.; Qin, Z.H.; Qiu, Y.; Qu, Z.; Quadrilatero, J.; Quinn, F.; Raben, N.; Rabinowich, H.; Radogna, F.; Ragusa, M.J.; Rahmani, M.; Raina, K.; Ramanadham, S.; Ramesh, R.; Rami, A.; Randall-Demllo, S.; Randow, F.; Rao, H.; Rao, V.A.; Rasmussen, B.B.; Rasse, T.M.; Ratovitski, E.A.; Rautou, P.E.; Ray, S.K.; Razani, B.; Reed, B.H.; Reggiori, F.; Rehm, M.; Reichert, A.S.; Rein, T.; Reiner, D.J.; Reits, E.; Ren, J.; Ren, X.; Renna, M.; Reusch, J.E.B.; Revuelta, J.L.; Reyes, L.; Rezaie, A.R.; Richards, R.I.; Richardson, R.; Richetta, C.; Riehle, M.A.; Rihn, B.H.; Rikihisa, Y.; Riley, B.E.; Rimbach, G.; Rippo, M.R.; Ritis, K.; Rizzi, F.; Rizzo, E.; Roach, P.J.; Robbins, J.; Roberge, M.; Roca, G.; Roccheri, M.C.; Rocha, S.; Rodrigues, C.M.P.; Rodríguez, C.I.; De Córdoba, S.R.; Rodriguez-Muela, N.; Roelofs, J.; Rogov, V.V.; Rohn, T.T.; Rohrer, B.; Romanelli, D.; Romani, L.; Romano, P.S.; Roncero, M.I.G.; Rosa, J.L.; Rosello, A.; Rosen, K.V.; Rosenstiel, P.; Rost-Roszkowska, M.M.; Roth, K.A.; Roué, G.; Rouis, M.; Rouschop, K.M.A.; Ruan, D.T.; Ruano, D.; Rubinsztein, D.C.; Rucker, E.B.; Rudich, A.; Rudolf, E.; Rudolf, R.; Ruegg, M.A.; Ruiz-Roldan, C.; Ruparelia, A.A.; Rusmini, P.; Russ, D.W.; Russo, G.L.; Russo, G.; Russo, R.; Rusten, T.E.; Ryabovol, V.; Ryan, K.M.; Ryter, S.W.; Sabatini, D.M.; Sacher, M.; Sachse, C.; Sack, M.N.; Sadoshima, J.; Saftig, P.; Sagi-Eisenberg, R.; Sahni, S.; Saikumar, P.; Saito, T.; Saitoh, T.; Sakakura, K.; Sakoh-Nakatogawa, M.; Sakuraba, Y.; Salazar-Roa, M.; Salomoni, P.; Saluja, A.K.; Salvaterra, P.M.; Salvioli, R.; Samali, A.; Sanchez, A.M.J.; Sánchez-Alcázar, J.A.; Sánchez-Prieto, R.; Sandri, M.; Sanjuan, M.A.; Santaguida, S.; Santambrogio, L.; Santoni, G.; Dos Santos, C.N.; Saran, S.; Sardiello, M.; Sargent, G.; Sarkar, P.; Sarkar, S.; Sarrias, M.R.; Sarwal, M.M.; Sasakawa, C.; Sasaki, M.; Sass, M.; Sato, K.; Sato, M.; Satriano, J.; Savaraj, N.; Saveljeva, S.; Schaefer, L.; Schaible, U.E.; Scharl, M.; Schätzl, H.M.; Schekman, R.; Scheper, W.; Schiavi, A.; Schipper, H.M.; Schmeisser, H.; Schmidt, J.; Schmitz, I.; Schneider, B.E.; Schneider, E.M.; Schneider, J.L.; Schon, E.A.; Schönenberger, M.J.; Schönthal, A.H.; Schorderet, D.F.; Schröder, B.; Schuck, S.; Schulze, R.J.; Schwarten, M.; Schwarz, T.L.; Sciarretta, S.; Scotto, K.; Scovassi, A.I.; Screaton, R.A.; Screen, M.; Seca, H.; Sedej, S.; Segatori, L.; Segev, N.; Seglen, P.O.; Seguí-Simarro, J.M.; Segura-Aguilar, J.; Seiliez, I.; Seki, E.; Sell, C.; Semenkovich, C.F.; Semenza, G.L.; Sen, U.; Serra, A.L.; Serrano-Puebla, A.; Sesaki, H.; Setoguchi, T.; Settembre, C.; Shacka, J.J.; Shajahan-Haq, A.N.; Shapiro, I.M.; Sharma, S.; She, H.; Shen, C.K.J.; Shen, C.C.; Shen, H.M.; Shen, S.; Shen, W.; Sheng, R.; Sheng, X.; Sheng, Z.H.; Shepherd, T.G.; Shi, J.; Shi, Q.; Shi, Q.; Shi, Y.; Shibutani, S.; Shibuya, K.; Shidoji, Y.; Shieh, J.J.; Shih, C.M.; Shimada, Y.; Shimizu, S.; Shin, D.W.; Shinohara, M.L.; Shintani, M.; Shintani, T.; Shioi, T.; Shirabe, K.; Shiri-Sverdlov, R.; Shirihai, O.S.; Shore, G.C.; Shu, C.W.; Shukla, D.; Sibirny, A.A.; Sica, V.; Sigurdson, C.J.; Sigurdsson, E.M.; Sijwali, P.S.; Sikorska, B.; Silveira, W.A.; Silvente-Poirot, S.; Silverman, G.A.; Simak, J.; Simmet, T.; Simon, A.K.; Simon, H.U.; Simone, C.; Simons, M.; Simonsen, A.; Singh, R.; Singh, S.V.; Singh, S.K.; Sinha, D.; Sinha, S.; Sinicrope, F.A.; Sirko, A.; Sirohi, K.; Sishi, B.J.N.; Sittler, A.; Siu, P.M.; Sivridis, E.; Skwarska, A.; Slack, R.S.; Slaninová, I.; Slavov, N.; Smaili, S.S.; Smalley, K.S.M.; Smith, D.R.; Soenen, S.J.; Soleimanpour, S.A.; Solhaug, A.; Somasundaram, K.; Son, J.H.; Sonawane, A.; Song, C.; Song, F.; Song, H.K.; Song, J.X.; Song, W.; Soo, K.Y.; Sood, A.K.; Soong, T.W.; Soontornniyomkij, V.; Sorice, M.; Sotgia, F.; Soto-Pantoja, D.R.; Sotthibundhu, A.; Sousa, M.J.; Spaink, H.P.; Span, P.N.; Spang, A.; Sparks, J.D.; Speck, P.G.; Spector, S.A.; Spies, C.D.; Springer, W.; Clair, D.S.; Stacchiotti, A.; Staels, B.; Stang, M.T.; Starczynowski, D.T.; Starokadomskyy, P.; Steegborn, C.; Steele, J.W.; Stefanis, L.; Steffan, J.S.; Stellrecht, C.M.; Stenmark, H.; Stepkowski, T.M.; Stern, S.T.; Stevens, C.; Stockwell, B.R.; Stoka, V.; Storchova, Z.; Stork, B.; Stratoulias, V.; Stravopodis, D.J.; Strnad, P.; Strohecker, A.M.; Ström, A.L.; Stromhaug, P.; Stulik, J.; Su, Y.X.; Su, Z.; Subauste, C.S.; Subramaniam, S.; Sue, C.M.; Suh, S.W.; Sui, X.; Sukseree, S.; Sulzer, D.; Sun, F.L.; Sun, J.; Sun, J.; Sun, S.Y.; Sun, Y.; Sun, Y.; Sun, Y.; Sundaramoorthy, V.; Sung, J.J.Y.; Suzuki, H.; Suzuki, K.; Suzuki, N.; Suzuki, T.; Suzuki, Y.J.; Swanson, M.S.; Swanton, C.; Swärd, K.; Swarup, G.; Sweeney, S.T.; Sylvester, P.W.; Szatmari, Z.; Szegezdi, E.; Szlosarek, P.W.; Taegtmeyer, H.; Tafani, M.; Taillebourg, E.; Tait, S.W.G.; Takács-Vellai, K.; Takahashi, Y.; Takáts, S.; Takemura, G.; Takigawa, N.; Talbot, N.J.; Tamagno, E.; Tamburini, J.; Tan, C.P.; Tan, L.; Tan, M.L.; Tan, M.; Tan, Y.J.; Tanaka, K.; Tanaka, M.; Tang, D.; Tang, D.; Tang, G.; Tanida, I.; Tanji, K.; Tannous, B.A.; Tapia, J.A.; Tasset-Cuevas, I.; Tatar, M.; Tavassoly, I.; Tavernarakis, N.; Taylor, A.; Taylor, G.S.; Taylor, G.A.; Taylor, J.P.; Taylor, M.J.; Tchetina, E.V.; Tee, A.R.; Teixeira-Clerc, F.; Telang, S.; Tencomnao, T.; Teng, B.B.; Teng, R.J.; Terro, F.; Tettamanti, G.; Theiss, A.L.; Theron, A.E.; Thomas, K.J.; Thomé, M.P.; Thomes, P.G.; Thorburn, A.; Thorner, J.; Thum, T.; Thumm, M.; Thurston, T.L.M.; Tian, L.; Till, A.; Ting, J.P.Y.; Ting, J.P.Y.; Titorenko, V.I.; Toker, L.; Toldo, S.; Tooze, S.A.; Topisirovic, I.; Torgersen, M.L.; Torosantucci, L.; Torriglia, A.; Torrisi, M.R.; Tournier, C.; Towns, R.; Trajkovic, V.; Travassos, L.H.; Triola, G.; Tripathi, D.N.; Trisciuoglio, D.; Troncoso, R.; Trougakos, I.P.; Truttmann, A.C.; Tsai, K.J.; Tschan, M.P.; Tseng, Y.H.; Tsukuba, T.; Tsung, A.; Tsvetkov, A.S.; Tu, S.; Tuan, H.Y.; Tucci, M.; Tumbarello, D.A.; Turk, B.; Turk, V.; Turner, R.F.B.; Tveita, A.A.; Tyagi, S.C.; Ubukata, M.; Uchiyama, Y.; Udelnow, A.; Ueno, T.; Umekawa, M.; Umemiya-Shirafuji, R.; Underwood, B.R.; Ungermann, C.; Ureshino, R.P.; Ushioda, R.; Uversky, V.N.; Uzcátegui, N.L.; Vaccari, T.; Vaccaro, M.I.; Váchová, L.; Vakifahmetoglu-Norberg, H.; Valdor, R.; Valente, E.M.; Vallette, F.; Valverde, A.M.; Van den Berghe, G.; Van Den Bosch, L.; van den Brink, G.R.; van der Goot, F.G.; van der Klei, I.J.; van der Laan, L.J.W.; van Doorn, W.G.; van Egmond, M.; van Golen, K.L.; Van Kaer, L.; Campagne, M.L.; Vandenabeele, P.; Vandenberghe, W.P.; Vanhorebeek, I.; Varela-Nieto, I.; Vasconcelos, M.H.; Vasko, R.; Vavvas, D.G.; Vega-Naredo, I.; Velasco, G.; Velentzas, A.D.; Velentzas, P.D.; Vellai, T.; Vellenga, E.; Vendelbo, M.H.; Venkatachalam, K.; Ventura, N.; Ventura, S.; Veras, P.S.T.; Verdier, M.; Vertessy, B.G.; Viale, A.; Vidal, M.; Vieira, H.L.A.; Vierstra, R.D.; Vigneswaran, N.; Vij, N.; Vila, M.; Villar, M.; Villar, V.H.; Villarroya, J.; Vindis, C.; Viola, G.; Viscomi, M.T.; Vitale, G.; Vogl, D.T.; Voitsekhovskaja, O.V.; von Haefen, C.; von Schwarzenberg, K.; Voth, D.E.; Vouret-Craviari, V.; Vuori, K.; Vyas, J.M.; Waeber, C.; Walker, C.L.; Walker, M.J.; Walter, J.; Wan, L.; Wan, X.B.; Wang, B.; Wang, C.; Wang, C.Y.; Wang, C.; Wang, C.; Wang, C.; Wang, D.; Wang, F.; Wang, F.; Wang, G.; Wang, H.J.; Wang, H.; Wang, H.G.; Wang, H.; Wang, H.D.; Wang, J.; Wang, J.; Wang, M.; Wang, M.Q.; Wang, P.Y.; Wang, P.; Wang, R.C.; Wang, S.; Wang, T.F.; Wang, X.; Wang, X.J.; Wang, X.W.; Wang, X.; Wang, X.; Wang, Y.; Wang, Y.; Wang, Y.; Wang, Y.J.; Wang, Y.; Wang, Y.; Wang, Y.T.; Wang, Y.; Wang, Z.N.; Wappner, P.; Ward, C.; Ward, D.M.V.; Warnes, G.; Watada, H.; Watanabe, Y.; Watase, K.; Weaver, T.E.; Weekes, C.D.; Wei, J.; Weide, T.; Weihl, C.C.; Weindl, G.; Weis, S.N.; Wen, L.P.; Wen, X.; Wen, Y.; Westermann, B.; Weyand, C.M.; White, A.R.; White, E.; Whitton, J.L.; Whitworth, A.J.; Wiels, J.; Wild, F.; Wildenberg, M.E.; Wileman, T.; Wilkinson, D.S.; Wilkinson, S.; Willbold, D.; Williams, C.; Williams, K.; Williamson, P.R.; Winklhofer, K.F.; Witkin, S.S.; Wohlgemuth, S.E.; Wollert, T.; Wolvetang, E.J.; Wong, E.; Wong, G.W.; Wong, R.W.; Wong, V.K.W.; Woodcock, E.A.; Wright, K.L.; Wu, C.; Wu, D.; Wu, G.S.; Wu, J.; Wu, J.; Wu, M.; Wu, M.; Wu, S.; Wu, W.K.K.; Wu, Y.; Wu, Z.; Xavier, C.P.R.; Xavier, R.J.; Xia, G.X.; Xia, T.; Xia, W.; Xia, Y.; Xiao, H.; Xiao, J.; Xiao, S.; Xiao, W.; Xie, C.M.; Xie, Z.; Xie, Z.; Xilouri, M.; Xiong, Y.; Xu, C.; Xu, C.; Xu, F.; Xu, H.; Xu, H.; Xu, J.; Xu, J.; Xu, J.; Xu, L.; Xu, X.; Xu, Y.; Xu, Y.; Xu, Z.X.; Xu, Z.; Xue, Y.; Yamada, T.; Yamamoto, A.; Yamanaka, K.; Yamashina, S.; Yamashiro, S.; Yan, B.; Yan, B.; Yan, X.; Yan, Z.; Yanagi, Y.; Yang, D.S.; Yang, J.M.; Yang, L.; Yang, M.; Yang, P.M.; Yang, P.; Yang, Q.; Yang, W.; Yang, W.Y.; Yang, X.; Yang, Y.; Yang, Y.; Yang, Z.; Yang, Z.; Yao, M.C.; Yao, P.J.; Yao, X.; Yao, Z.; Yao, Z.; Yasui, L.S.; Ye, M.; Yedvobnick, B.; Yeganeh, B.; Yeh, E.S.; Yeyati, P.L.; Yi, F.; Yi, L.; Yin, X.M.; Yip, C.K.; Yoo, Y.M.; Yoo, Y.H.; Yoon, S.Y.; Yoshida, K.I.; Yoshimori, T.; Young, K.H.; Yu, H.; Yu, J.J.; Yu, J.T.; Yu, J.; Yu, L.; Yu, W.H.; Yu, X.F.; Yu, Z.; Yuan, J.; Yuan, Z.M.; Yue, B.Y.J.T.; Yue, J.; Yue, Z.; Zacks, D.N.; Zacksenhaus, E.; Zaffaroni, N.; Zaglia, T.; Zakeri, Z.; Zecchini, V.; Zeng, J.; Zeng, M.; Zeng, Q.; Zervos, A.S.; Zhang, D.D.; Zhang, F.; Zhang, G.; Zhang, G.C.; Zhang, H.; Zhang, H.; Zhang, H.; Zhang, J.; Zhang, J.; Zhang, J.; Zhang, J.P.; Zhang, L.; Zhang, L.; Zhang, L.; Zhang, M.Y.; Zhang, X.; Zhang, X.D.; Zhang, Y.; Zhang, Y.; Zhang, Y.; Zhang, Y.; Zhang, Y.; Zhao, M.; Zhao, W.L.; Zhao, X.; Zhao, Y.G.; Zhao, Y.; Zhao, Y.; Zhao, Y.X.; Zhao, Z.J.; Zhao, Z.J.; Zheng, D.; Zheng, X.L.; Zheng, X.; Zhivotovsky, B.; Zhong, Q.; Zhou, G.Z.; Zhou, G.; Zhou, H.; Zhou, S.F.; Zhou, X.J.; Zhu, H.; Zhu, H.; Zhu, W.G.; Zhu, W.; Zhu, X.F.; Zhu, Y.; Zhuang, S.M.; Zhuang, X.; Ziparo, E.; Zois, C.E.; Zoladek, T.; Zong, W.X.; Zorzano, A.; Zughaier, S.M.},

note = {3677},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-85054826264,

title = {Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356},

author = { I. Poprawa and M.M. Rost-Roszkowska and D.J. Klionsky and K. Abdelmohsen and A. Abe and M.J. Abedin and H. Abeliovich and A. Acevedo-Arozena and H. Adachi and C.M. Adams and P.D. Adams and K. Adeli and P.J. Adhihetty and S.G. Adler and G. Agam and R. Agarwal and M.K. Aghi and M. Agnello and P. Agostinis and P.V. Aguilar and J.A. Aguirre-Ghiso and E.M. Airoldi and S. Ait-Si-Ali and T. Akematsu and E.T. Akporiaye and M. Al-Rubeai and G.M. Albaiceta and C. Albanese and D. Albani and M.L. Albert and J. Aldudo and H. Algül and M. Alirezaei and I. Alloza and A. Almasan and M. Almonte-Beceril and E.S. Alnemri and C. Alonso and N. Altan-Bonnet and D.C. Altieri and S. Alvarez and L. Alvarez-Erviti and S. Alves and G. Amadoro and A. Amano and C. Amantini and S. Ambrosio and I. Amelio and A.O. Amer and M. Amessou and A. Amon and Z. An and Authors. Other},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85054826264&doi=10.1080%2f15548627.2016.1147886&partnerID=40&md5=14fd1b79eff1a7ce4a3f523f1da1853d},

doi = {10.1080/15548627.2016.1147886},

issn = {15548627},

year  = {2016},

date = {2016-01-01},

journal = {Autophagy},

volume = {12},

number = {2},

pages = {443-},

publisher = {Taylor and Francis Inc.},

abstract = {[No abstract available] 

Authors: Klionsky, D.J.; Abdelmohsen, K.; Abe, A.; Abedin, M.J.; Abeliovich, H.; Acevedo-Arozena, A.; Adachi, H.; Adams, C.M.; Adams, P.D.; Adeli, K.; Adhihetty, P.J.; Adler, S.G.; Agam, G.; Agarwal, R.; Aghi, M.K.; Agnello, M.; Agostinis, P.; Aguilar, P.V.; Aguirre-Ghiso, J.A.; Airoldi, E.M.; Ait-Si-Ali, S.; Akematsu, T.; Akporiaye, E.T.; Al-Rubeai, M.; Albaiceta, G.M.; Albanese, C.; Albani, D.; Albert, M.L.; Aldudo, J.; Algül, H.; Alirezaei, M.; Alloza, I.; Almasan, A.; Almonte-Beceril, M.; Alnemri, E.S.; Alonso, C.; Altan-Bonnet, N.; Altieri, D.C.; Alvarez, S.; Alvarez-Erviti, L.; Alves, S.; Amadoro, G.; Amano, A.; Amantini, C.; Ambrosio, S.; Amelio, I.; Amer, A.O.; Amessou, M.; Amon, A.; An, Z.; Anania, F.A.; Andersen, S.U.; Andley, U.P.; Andreadi, C.K.; Andrieu-Abadie, N.; Anel, A.; Ann, D.K.; Anoopkumar-Dukie, S.; Antonioli, M.; Aoki, H.; Apostolova, N.; Aquila, S.; Aquilano, K.; Araki, K.; Arama, E.; Aranda, A.; Araya, J.; Arcaro, A.; Arias, E.; Arimoto, H.; Ariosa, A.R.; Armstrong, J.L.; Arnould, T.; Arsov, I.; Asanuma, K.; Askanas, V.; Asselin, E.; Atarashi, R.; Atherton, S.S.; Atkin, J.D.; Attardi, L.D.; Auberger, P.; Auburger, G.; Aurelian, L.; Autelli, R.; Avagliano, L.; Avantaggiati, M.L.; Avrahami, L.; Azad, N.; Awale, S.; Bachetti, T.; Backer, J.M.; Bae, D.H.; Bae, J.S.; Bae, O.N.; Bae, S.H.; Baehrecke, E.H.; Baek, S.H.; Baghdiguian, S.; Bagniewska-Zadworna, A.; Bai, H.; Bai, J.; Bai, X.Y.; Bailly, Y.; Balaji, K.N.; Balduini, W.; Ballabio, A.; Balzan, R.; Banerjee, R.; Bánhegyi, G.; Bao, H.; Barbeau, B.; Barrachina, M.D.; Barreiro, E.; Bartel, B.; Bartolomé, A.; Bassham, D.C.; Bassi, M.T.; Bast Jr. R.C.; Basu, A.; Batista, M.T.; Batoko, H.; Battino, M.; Bauckman, K.; Baumgarner, B.L.; Bayer, K.U.; Beale, R.; Beaulieu, J.F.; Beck, G.R.; Becker, C.; Beckham, J.D.; Bédard, P.A.; Bednarski, P.J.; Begley, T.J.; Behl, C.; Behrends, C.; Behrens, G.M.N.; Behrns, K.E.; Bejarano, E.; Belaid, A.; Belleudi, F.; Bénard, G.; Berchem, G.; Bergamaschi, D.; Bergami, M.; Berkhout, B.; Berliocchi, L.; Bernard, A.; Bernard, M.; Bernassola, F.; Bertolotti, A.; Bess, A.S.; Besteiro, S.; Bettuzzi, S.; Bhalla, S.; Bhattacharyya, S.; Bhutia, S.K.; Biagosch, C.; Bianchi, M.W.; Biard-Piechaczyk, M.; Billes, V.; Bincoletto, C.; Bingol, B.; Bird, S.W.; Bitoun, M.; Bjedov, I.; Blackstone, C.; Blanc, L.; Blanco, G.A.; Blomhoff, H.K.; Boada-Romero, E.; Böckler, S.; Boes, M.; Boesze-Battaglia, K.; Boise, L.H.; Bolino, A.; Boman, A.; Bonaldo, P.; Bordi, M.; Bosch, J.; Botana, L.M.; Botti, J.; Bou, G.; Bouché, M.; Bouchecareilh, M.; Boucher, M.J.; Boulton, M.E.; Bouret, S.G.; Boya, P.; Boyer-Guittaut, M.; Bozhkov, P.V.; Brady, N.R.; Braga, V.M.M.; Brancolini, C.; Braus, G.H.; Bravo-San-Pedro, J.M.; Brennan, L.A.; Bresnick, E.H.; Brest, P.; Bridges, D.; Bringer, M.A.; Brini, M.; Brito, G.C.; Brodin, B.; Brookes, P.S.; Brown, E.J.; Brown, K.; Broxmeyer, H.E.; Bruhat, A.; Brum, P.C.; Brumell, J.H.; Brunetti-Pierri, N.; Bryson-Richardson, R.J.; Buch, S.; Buchan, A.M.; Budak, H.; Bulavin, D.V.; Bultman, S.J.; Bultynck, G.; Bumbasirevic, V.; Burelle, Y.; Burke, R.E.; Burmeister, M.; Bütikofer, P.; Caberlotto, L.; Cadwell, K.; Cahová, M.; Cai, D.; Cai, J.; Cai, Q.; Calatayud, S.; Camougrand, N.; Campanella, M.; Campbell, G.R.; Campbell, M.; Campello, S.; Candau, R.; Caniggia, I.; Cantoni, L.; Cao, L.; Caplan, A.B.; Caraglia, M.; Cardinali, C.; Cardoso, S.M.; Carew, J.S.; Carleton, L.A.; Carlin, C.R.; Carloni, S.; Carlsson, S.R.; Carmona-Gutierrez, D.; Carneiro, L.A.M.; Carnevali, O.; Carra, S.; Carrier, A.; Carroll, B.; Casas, C.; Casas, J.; Cassinelli, G.; Castets, P.; Castro-Obregon, S.; Cavallini, G.; Ceccherini, I.; Cecconi, F.; Cederbaum, A.I.; Ceña, V.; Cenci, S.; Cerella, C.; Cervia, D.; Cetrullo, S.; Chaachouay, H.; Chae, H.J.; Chagin, A.S.; Chai, C.Y.; Chakrabarti, G.; Chamilos, G.; Chan, E.Y.W.; Chan, M.T.V.; Chandra, D.; Chandra, P.; Chang, C.P.; Chang, R.C.C.; Chang, T.Y.; Chatham, J.C.; Chatterjee, S.; Chauhan, S.; Che, Y.; Cheetham, M.E.; Cheluvappa, R.; Chen, C.J.; Chen, G.; Chen, G.C.; Chen, G.Q.; Chen, H.; Chen, J.W.; Chen, J.K.; Chen, M.; Chen, M.; Chen, P.; Chen, Q.; Chen, Q.; Chen, S.D.; Chen, S.; Chen, S.S.L.; Chen, W.; Chen, W.J.; Chen, W.Q.; Chen, W.; Chen, X.; Chen, Y.H.; Chen, Y.G.; Chen, Y.; Chen, Y.; Chen, Y.; Chen, Y.J.; Chen, Y.Q.; Chen, Y.; Chen, Z.; Chen, Z.; Cheng, A.; Cheng, C.H.K.; Cheng, H.; Cheong, H.; Cherry, S.; Chesney, J.; Cheung, C.H.A.; Chevet, E.; Chi, H.C.; Chi, S.G.; Chiacchiera, F.; Chiang, H.L.; Chiarelli, R.; Chiariello, M.; Chieppa, M.; Chin, L.S.; Chiong, M.; Chiu, G.N.C.; Cho, D.H.; Cho, S.G.; Cho, W.C.; Cho, Y.Y.; Cho, Y.S.; Choi, A.M.K.; Choi, E.J.; Choi, E.K.; Choi, J.; Choi, M.E.; Choi, S.I.; Chou, T.F.; Chouaib, S.; Choubey, D.; Choubey, V.; Chow, K.C.; Chowdhury, K.; Chu, C.T.; Chuang, T.H.; Chun, T.; Chung, H.; Chung, T.; Chung, Y.L.; Chwae, Y.J.; Cianfanelli, V.; Ciarcia, R.; Ciechomska, I.A.; Ciriolo, M.R.; Cirone, M.; Claerhout, S.; Clague, M.J.; Cl� ria, J.; Clarke, P.G.H.; Clarke, R.; Clementi, E.; Cleyrat, C.; Cnop, M.; Coccia, E.M.; Cocco, T.; Codogno, P.; Coers, J.; Cohen, E.E.W.; Colecchia, D.; Coletto, L.; Coll, N.S.; Colucci-Guyon, E.; Comincini, S.; Condello, M.; Cook, K.L.; Coombs, G.H.; Cooper, C.D.; Cooper, J.M.; Coppens, I.; Corasaniti, M.T.; Corazzari, M.; Corbalan, R.; Corcelle-Termeau, E.; Cordero, M.D.; Corral-Ramos, C.; Corti, O.; Cossarizza, A.; Costelli, P.; Costes, S.; Cotman, S.L.; Coto-Montes, A.; Cottet, S.; Couve, E.; Covey, L.R.; Cowart, L.A.; Cox, J.S.; Coxon, F.P.; Coyne, C.B.; Cragg, M.S.; Craven, R.J.; Crepaldi, T.; Crespo, J.L.; Criollo, A.; Crippa, V.; Cruz, M.T.; Cuervo, A.M.; Cuezva, J.M.; Cui, T.; Cutillas, P.R.; Czaja, M.J.; Czyzyk-Krzeska, M.F.; Dagda, R.K.; Dahmen, U.; Dai, C.; Dai, W.; Dai, Y.; Dalby, K.N.; Valle, L.D.; Dalmasso, G.; D'amelio, M.; Damme, M.; Darfeuille-Michaud, A.; Dargemont, C.; Darley-Usmar, V.M.; Dasarathy, S.; Dasgupta, B.; Dash, S.; Dass, C.R.; Davey, H.M.; Davids, L.M.; Dávila, D.; Davis, R.J.; Dawson, T.M.; Dawson, V.L.; Daza, P.; de Belleroche, J.; de Figueiredo, P.; de Figueiredo, R.C.B.Q.; de la Fuente, J.; De Martino, L.; De Matteis, A.; De Meyer, G.R.Y.; De Milito, A.; De Santi, M.; de Souza, W.; De Tata, V.; De Zio, D.; Debnath, J.; Dechant, R.; Decuypere, J.P.; Deegan, S.; Dehay, B.; Del Bello, B.; Del Re, D.P.; Delage-Mourroux, R.; Delbridge, L.M.D.; Deldicque, L.; Delorme-Axford, E.; Deng, Y.; Dengjel, J.; Denizot, M.; Dent, P.; Der, C.J.; Deretic, V.; Derrien, B.; Deutsch, E.; Devarenne, T.P.; Devenish, R.J.; Di Bartolomeo, S.; Di Daniele, N.; Di Domenico, F.; Di Nardo, A.; Di Paola, S.; Di Pietro, A.; Di Renzo, L.; Di Antonio, A.; Díaz-Araya, G.; Díaz-Laviada, I.; Diaz-Meco, M.T.; Diaz-Nido, J.; Dickey, C.A.; Dickson, R.C.; Diederich, M.; Digard, P.; Dikic, I.; Dinesh-Kumar, S.P.; Ding, C.; Ding, W.X.; Ding, Z.; Dini, L.; Distler, J.H.W.; Diwan, A.; Djavaheri-Mergny, M.; Dmytruk, K.; Dobson, R.C.J.; Doetsch, V.; Dokladny, K.; Dokudovskaya, S.; Donadelli, M.; Dong, X.C.; Dong, X.; Dong, Z.; Donohue, T.M.; Donohue-Jr, T.M.; Doran, K.S.; D'orazi, G.; Dorn, G.W.; Dosenko, V.; Dridi, S.; Drucker, L.; Du, J.; Du, L.L.; Du, L.; du Toit, A.; Dua, P.; Duan, L.; Duann, P.; Dubey, V.K.; Duchen, M.R.; Duchosal, M.A.; Duez, H.; Dugail, I.; Dumit, V.I.; Duncan, M.C.; Dunlop, E.A.; Dunn, W.A.; Dupont, N.; Dupuis, L.; Durán, R.V.; Durcan, T.M.; Duvezin-Caubet, S.; Duvvuri, U.; Eapen, V.; Ebrahimi-Fakhari, D.; Echard, A.; Eckhart, L.; Edelstein, C.L.; Edinger, A.L.; Eichinger, L.; Eisenberg, T.; Eisenberg-Lerner, A.; Eissa, N.T.; El-Deiry, W.S.; El-Khoury, V.; Elazar, Z.; Eldar-Finkelman, H.; Elliott, C.J.H.; Emanuele, E.; Emmenegger, U.; Engedal, N.; Engelbrecht, A.M.; Engelender, S.; Enserink, J.M.; Erdmann, R.; Erenpreisa, J.; Eri, R.; Eriksen, J.L.; Erman, A.; Escalante, R.; Eskelinen, E.L.; Espert, L.; Esteban-Martínez, L.; Evans, T.J.; Fabri, M.; Fabrias, G.; Fabrizi, C.; Facchiano, A.; Færgeman, N.J.; Faggioni, A.; Fairlie, W.D.; Fan, C.; Fan, D.; Fan, J.; Fang, S.; Fanto, M.; Fanzani, A.; Farkas, T.; Faure, M.; Favier, F.B.; Fearnhead, H.; Federici, M.; Fei, E.; Felizardo, T.C.; Feng, H.; Feng, Y.; Feng, Y.; Ferguson, T.A.; Fernández, Á.F.; Fernandez-Barrena, M.G.; Fernandez-Checa, J.C.; Fernández-López, A.; Fernandez-Zapico, M.E.; Feron, O.; Ferraro, E.; Ferreira-Halder, C.V.; Fésüs, L.; Feuer, R.; Fiesel, F.C.; Filippi-Chiela, E.C.; Filomeni, G.; Fimia, G.M.; Fingert, J.H.; Finkbeiner, S.; Finkel, T.; Fiorito, F.; Fisher, P.B.; Flajolet, M.; Flamigni, F.; Florey, O.; Florio, S.; Floto, R.A.; Folini, M.; Follo, C.; Fon, E.A.; Fornai, F.; Fortunato, F.; Fraldi, A.; Franco, R.; Francois, A.; François, A.; Frankel, L.B.; Fraser, I.D.C.; Frey, N.; Freyssenet, D.G.; Frezza, C.; Friedman, S.L.; Frigo, D.E.; Fu, D.; Fuentes, J.M.; Fueyo, J.; Fujitani, Y.; Fujiwara, Y.; Fujiya, M.; Fukuda, M.; Fulda, S.; Fusco, C.; Gabryel, B.; Gaestel, M.; Gailly, P.; Gajewska, M.; Galadari, S.; Galili, G.; Galindo, I.; Galindo, M.F.; Galliciotti, G.; Galluzzi, L.; Galluzzi, L.; Galy, V.; Gammoh, N.; Gandy, S.; Ganesan, A.K.; Ganesan, S.; Ganley, I.G.; Gannagé, M.; Gao, F.B.; Gao, F.; Gao, J.X.; Nannig, L.G.; Véscovi, E.G.; Garcia-Macía, M.; Garcia-Ruiz, C.; Garg, A.D.; Garg, P.K.; Gargini, R.; Gassen, N.C.; Gatica, D.; Gatti, E.; Gavard, J.; Gavathiotis, E.; Ge, L.; Ge, P.; Ge, S.; Gean, P.W.; Gelmetti, V.; Genazzani, A.A.; Geng, J.; Genschik, P.; Gerner, L.; Gestwicki, J.E.; Gewirtz, D.A.; Ghavami, S.; Ghigo, E.; Ghosh, D.; Giammarioli, A.M.; Giampieri, F.; Giampietri, C.; Giatromanolaki, A.N.; Gibbings, D.J.; Gibellini, L.; Gibson, S.B.; Ginet, V.; Giordano, A.; Giorgini, F.; Giovannetti, E.; Girardin, S.E.; Gispert, S.; Giuliano, S.; Gladson, C.L.; Glavic, A.; Gleave, M.; Godefroy, N.; Gogal, R.M.; Gokulan, K.; Goldman, G.H.; Goletti, D.; Goligorsky, M.S.; Gomes, A.V.; Gomes, L.C.; Gomez, H.; Gomez-Manzano, C.; Gómez-Sánchez, R.; Gonçalves, D.A.P.; Goncu, E.; Gong, Q.; Gongora, C.; Gonzalez, C.B.; Gonzalez-Alegre, P.; Gonzalez-Cabo, P.; González-Polo, R.A.; Goping, I.S.; Gorbea, C.; Gorbunov, N.V.; Goring, D.R.; Gorman, A.M.; Gorski, S.M.; Goruppi, S.; Goto-Yamada, S.; Gotor, C.; Gottlieb, R.A.; Gozes, I.; Gozuacik, D.; Graba, Y.; Graef, M.; Granato, G.E.; Grant, G.D.; Grant, S.; Gravina, G.L.; Green, D.R.; Greenhough, A.; Greenwood, M.T.; Grimaldi, B.; Gros, F.; Grose, C.; Groulx, J.F.; Gruber, F.; Grumati, P.; Grune, T.; Guan, J.L.; Guan, K.L.; Guerra, B.; Guillen, C.; Gulshan, K.; Gunst, J.; Guo, C.; Guo, L.; Guo, M.; Guo, W.; Guo, X.G.; Gust, A.A.; Gustafsson, Å.B.; Gutierrez, E.; Gutierrez, M.G.; Gwak, H.S.; Haas, A.; Haber, J.E.; Hadano, S.; Hagedorn, M.; Hahn, D.R.; Halayko, A.J.; Hamacher-Brady, A.; Hamada, K.; Hamai, A.; Hamann, A.; Hamasaki, M.; Hamer, I.; Hamid, Q.; Hammond, E.M.; Han, F.; Han, W.; Handa, J.T.; Hanover, J.A.; Hansen, M.; Harada, M.; Harhaji-Trajkovic, L.; Harper, J.W.; Harrath, A.H.; Harris, A.L.; Harris, J.; Hasler, U.; Hasselblatt, P.; Hasui, K.; Hawley, R.G.; Hawley, T.S.; He, C.; He, C.Y.; He, F.; He, G.; He, R.R.; He, X.H.; He, Y.W.; He, Y.Y.; Heath, J.K.; Hébert, M.J.; Heinzen, R.A.; Helgason, G.V.; Hensel, M.; Henske, E.P.; Her, C.; Herman, P.K.; Hernández, A.; Hernandez, C.; Hernández-Tiedra, S.; Hetz, C.; Hiesinger, P.R.; Higaki, K.; Hilfiker, S.; Hill, B.G.; Hill, J.A.; Hill, W.D.; Hino, K.; Hofius, D.; Hofman, P.; Höglinger, G.U.; Höhfeld, J.; Holz, M.K.; Hong, Y.; Hood, D.A.; Hoozemans, J.J.M.; Hoppe, T.; Hsu, C.; Hsu, C.Y.; Hsu, L.C.; Hu, D.; Hu, G.; Hu, H.M.; Hu, H.; Hu, M.C.; Hu, Y.C.; Hu, Z.W.; Hua, F.; Hua, Y.; Huang, C.; Huang, H.L.; Huang, K.H.; Huang, K.Y.; Huang, S.; Huang, S.; Huang, W.P.; Huang, Y.R.; Huang, Y.; Huang, Y.; Huber, T.B.; Huebbe, P.; Huh, W.K.; Hulmi, J.J.; Hur, G.M.; Hurley, J.H.; Husak, Z.; Hussain, S.N.A.; Hussain, S.; Hwang, J.J.; Hwang, S.; Hwang, T.I.S.; Ichihara, A.; Imai, Y.; Imbriano, C.; Inomata, M.; Into, T.; Iovane, V.; Iovanna, J.L.; Iozzo, R.V.; Ip, N.Y.; Irazoqui, J.E.; Iribarren, P.; Isaka, Y.; Isakovic, A.J.; Ischiropoulos, H.; Isenberg, J.S.; Ishaq, M.; Ishida, H.; Ishii, I.; Ishmael, J.E.; Isidoro, C.; Isobe, K.I.; Isono, E.; Issazadeh-Navikas, S.; Itahana, K.; Itakura, E.; Ivanov, A.I.; Iyer, A.K.V.; Izquierdo, J.M.; Izumi, Y.; Izzo, V.; Jäättelä, M.; Jaber, N.; Jackson, D.J.; Jackson, W.T.; Jacob, T.G.; Jacques, T.S.; Jagannath, C.; Jain, A.; Jana, N.R.; Jang, B.K.; Jani, A.; Janji, B.; Jannig, P.R.; Jansson, P.J.; Jean, S.; Jendrach, M.; Jeon, J.H.; Jessen, N.; Jeung, E.B.; Jia, K.; Jia, L.; Jiang, H.; Jiang, H.; Jiang, L.; Jiang, T.; Jiang, X.; Jiang, X.; Jiang, Y.; Jiang, Y.; Jiménez, A.; Jin, C.; Jin, H.; Jin, L.; Jin, M.; Jin, S.; Jinwal, U.K.; Jo, E.K.; Johansen, T.; Johnson, D.E.; Johnson, G.V.W.; Johnson, J.D.; Jonasch, E.; Jones, C.; Joosten, L.A.B.; Jordan, J.; Joseph, A.M.; Joseph, B.; Joubert, A.M.; Ju, D.; Ju, J.; Juan, H.F.; Juenemann, K.; Juhász, G.; Jung, H.S.; Jung, J.U.; Jung, Y.K.; Jungbluth, H.; Justice, M.J.; Jutten, B.; Kaakoush, N.O.; Kaarniranta, K.; Kaasik, A.; Kabuta, T.; Kaeffer, B.; Kågedal, K.; Kahana, A.; Kajimura, S.; Kakhlon, O.; Kalia, M.; Kalvakolanu, D.V.; Kamada, Y.; Kambas, K.; Kaminskyy, V.O.; Kampinga, H.H.; Kandouz, M.; Kang, C.; Kang, R.; Kang, T.C.; Kanki, T.; Kanneganti, T.D.; Kanno, H.; Kanthasamy, A.G.; Kantorow, M.; Kaparakis-Liaskos, M.; Kapuy, O.; Karantza, V.; Karim, M.R.; Karmakar, P.; Kaser, A.; Kaushik, S.; Kawula, T.; Kaynar, A.M.; Ke, P.Y.; Ke, Z.J.; Kehrl, J.H.; Keller, K.E.; Kemper, J.K.; Kenworthy, A.K.; Kepp, O.; Kern, A.; Kesari, S.; Kessel, D.; Ketteler, R.; Kettelhut, I.C.; Khambu, B.; Khan, M.M.; Khandelwal, V.K.M.; Khare, S.; Kiang, J.G.; Kiger, A.A.; Kihara, A.; Kim, A.L.; Kim, C.H.; Kim, D.R.; Kim, D.H.; Kim, E.K.; Kim, H.Y.; Kim, H.R.; Kim, J.S.; Kim, J.H.; Kim, J.C.; Kim, J.H.; Kim, K.W.; Kim, M.D.; Kim, M.M.; Kim, P.K.; Kim, S.W.; Kim, S.Y.; Kim, Y.S.; Kim, Y.; Kimchi, A.; Kimmelman, A.C.; Kimura, T.; King, J.S.; Kirkegaard, K.; Kirkin, V.; Kirshenbaum, L.A.; Kishi, S.; Kitajima, Y.; Kitamoto, K.; Kitaoka, Y.; Kitazato, K.; Kley, R.A.; Klimecki, W.T.; Klinkenberg, M.; Klucken, J.; Knævelsrud, H.; Knecht, E.; Knuppertz, L.; Ko, J.L.; Kobayashi, S.; Koch, J.C.; Koechlin-Ramonatxo, C.; Koenig, U.; Koh, Y.H.; Köhler, K.; Kohlwein, S.D.; Koike, M.; Komatsu, M.; Kominami, E.; Kong, D.; Kong, H.J.; Konstantakou, E.G.; Kopp, B.T.; Korcsmaros, T.; Korhonen, L.; Korolchuk, V.I.; Koshkina, N.V.; Kou, Y.; Koukourakis, M.I.; Koumenis, C.; Kovács, A.L.; Kovács, T.; Kovacs, W.J.; Koya, D.; Kraft, C.; Krainc, D.; Krämer, H.; Kravic-Stevovic, T.; Krek, W.; Kretz-Remy, C.; Krick, R.; Krishnamurthy, M.; Kriston-Vizi, J.; Kroemer, G.; Kruer, M.C.; Krüger, R.; Ktistakis, N.T.; Kuchitsu, K.; Kuhn, C.; Kumar, A.P.; Kumar, A.; Kumar, A.; Kumar, D.; Kumar, D.; Kumar, R.; Kumar, S.; Kundu, M.; Kung, H.J.; Kuno, A.; Kuo, S.H.; Kuret, J.; Kurz, T.; Kwok, T.; Kwon, T.K.; Kwon, Y.T.; Kyrmizi, I.; La Spada, A.R.; Lafont, F.; Lahm, T.; Lakkaraju, A.; Lam, T.; Lamark, T.; Lancel, S.; Landowski, T.H.; Lane, D.J.R.; Lane, J.D.; Lanzi, C.; Lapaquette, P.; Lapierre, L.R.; Laporte, J.; Laukkarinen, J.; Laurie, G.W.; Lavandero, S.; Lavie, L.; Lavoie, M.J.; Law, B.Y.K.; Law, H.K.W.; Law, K.B.; Layfield, R.; Lazo, P.A.; Le Cam, L.; Le Roch, K.G.; Le Stunff, H.; Leardkamolkarn, V.; Lecuit, M.; Lee, B.H.; Lee, C.H.; Lee, E.F.; Lee, G.M.; Lee, H.J.; Lee, H.; Lee, J.K.; Lee, J.; Lee, J.H.; Lee, J.H.; Lee, M.; Lee, M.S.; Lee, P.J.; Lee, S.W.; Lee, S.J.; Lee, S.J.; Lee, S.Y.; Lee, S.H.; Lee, S.S.; Lee, S.J.; Lee, S.; Lee, Y.R.; Lee, Y.J.; Lee, Y.H.; Leeuwenburgh, C.; Lefort, S.; Legouis, R.; Lei, J.; Lei, Q.Y.; Leib, D.A.; Leibowitz, G.; Lekli, I.; Lemaire, S.D.; Lemasters, J.J.; Lemberg, M.K.; Lemoine, A.; Leng, S.; Lenz, G.; Lenzi, P.; Lerman, L.O.; Barbato, D.L.; Leu, J.I.J.; Leung, H.Y.; Levine, B.; Lewis, P.A.; Lezoualch, F.; Li, C.; Li, F.; Li, F.J.; Li, J.; Li, K.; Li, L.; Li, M.; Li, Q.; Li, R.; Li, S.; Li, W.; Li, X.; Li, Y.; Lian, J.; Liang, C.; Liang, Q.; Liao, Y.; Liberal, J.; Liberski, P.P.; Lie, P.; Lieberman, A.P.; Lim, H.J.; Lim, K.L.; Lim, K.; Lima, R.T.; Lin, C.S.; Lin, C.F.; Lin, F.; Lin, F.; Lin, F.C.; Lin, K.; Lin, K.H.; Lin, P.H.; Lin, T.; Lin, W.W.; Lin, Y.S.; Lin, Y.; Linden, R.; Lindholm, D.; Lindqvist, L.M.; Lingor, P.; Linkermann, A.; Liotta, L.A.; Lipinski, M.M.; Lira, V.A.; Lisanti, M.P.; Liton, P.B.; Liu, B.; Liu, C.; Liu, C.F.; Liu, F.; Liu, H.J.; Liu, J.; Liu, J.J.; Liu, J.L.; Liu, K.; Liu, L.; Liu, L.; Liu, Q.; Liu, R.Y.; Liu, S.; Liu, S.; Liu, W.; Liu, X.D.; Liu, X.; Liu, X.H.; Liu, X.; Liu, X.; Liu, X.; Liu, Y.; Liu, Y.; Liu, Z.; Liu, Z.; Liuzzi, J.P.; Lizard, G.; Ljujic, M.; Lodhi, I.J.; Logue, S.E.; Lokeshwar, B.L.; Long, Y.C.; Lonial, S.; Loos, B.; López-Otín, C.; López-Vicario, C.; Lorente, M.; Lorenzi, P.L.; Lõrincz, P.; Los, M.; Lotze, M.T.; Lovat, P.E.; Lu, B.; Lu, B.; Lu, J.; Lu, Q.; Lu, S.M.; Lu, S.; Lu, Y.; Luciano, F.; Luckhart, S.; Lucocq, J.M.; Ludovico, P.; Lugea, A.; Lukacs, N.W.; Lum, J.J.; Lund, A.H.; Luo, H.; Luo, J.; Luo, S.; Luparello, C.; Lyons, T.; Ma, J.; Ma, Y.; Ma, Y.; Ma, Z.; Machado, J.; Machado-Santelli, G.M.; Macian, F.; MacIntosh, G.C.; MacKeigan, J.P.; Macleod, K.F.; MacMicking, J.D.; MacMillan-Crow, L.A.; Madeo, F.; Madesh, M.; Madrigal-Matute, J.; Maeda, A.; Maeda, T.; Maegawa, G.; Maellaro, E.; Maes, H.; Magariños, M.; Maiese, K.; Maiti, T.K.; Maiuri, L.; Maiuri, M.C.; Maki, C.G.; Malli, R.; Malorni, W.; Maloyan, A.; Mami-Chouaib, F.; Man, N.; Mancias, J.D.; Mandelkow, E.M.; Mandell, M.A.; Manfredi, A.A.; Manié, S.N.; Manzoni, C.; Mao, K.; Mao, Z.; Mao, Z.W.; Marambaud, P.; Marconi, A.M.; Marelja, Z.; Marfe, G.; Margeta, M.; Margittai, E.; Mari, M.; Mariani, F.V.; Marin, C.; Marinelli, S.; Mariño, G.; Markovic, I.; Marquez, R.; Martelli, A.M.; Martens, S.; Martin, K.R.; Martin, S.J.; Martin, S.; Martin-Acebes, M.A.; Martín-Sanz, P.; Martinand-Mari, C.; Martinet, W.; Martinez, J.; Martinez-Lopez, N.; Martinez-Outschoorn, U.; Martínez-Velázquez, M.; Martinez-Vicente, M.; Martins, W.K.; Mashima, H.; Mastrianni, J.A.; Matarese, G.; Matarrese, P.; Mateo, R.; Matoba, S.; Matsumoto, N.; Matsushita, T.; Matsuura, A.; Matsuzawa, T.; Mattson, M.P.; Matus, S.; Maugeri, N.; Mauvezin, C.; Mayer, A.; Maysinger, D.; Mazzolini, G.D.; McBrayer, M.K.; McCall, K.; McCormick, C.; McInerney, G.M.; McIver, S.C.; McKenna, S.L.; McMahon, J.J.; McNeish, I.A.; Mechta-Grigoriou, F.; Medema, J.P.; Medina, D.L.; Megyeri, K.; Mehrpour, M.; Mehta, J.L.; Mei, Y.; Meier, U.C.; Meijer, A.J.; Meléndez, A.; Melino, G.; Melino, S.; de Melo, E.J.T.; Mena, M.A.; Meneghini, M.D.; Menendez, J.A.; Menezes, R.; Meng, L.; Meng, L.H.; Meng, S.; Menghini, R.; Menko, A.S.; Menna-Barreto, R.F.S.; Menon, M.B.; Meraz-Ríos, M.A.; Merla, G.; Merlini, L.; Merlot, A.M.; Meryk, A.; Meschini, S.; Meyer, J.N.; Mi, M.T.; Miao, C.Y.; Micale, L.; Michaeli, S.; Michiels, C.; Migliaccio, A.R.; Mihailidou, A.S.; Mijaljica, D.; Mikoshiba, K.; Milan, E.; Miller-Fleming, L.; Mills, G.B.; Mills, I.G.; Minakaki, G.; Minassian, B.A.; Ming, X.F.; Minibayeva, F.; Minina, E.A.; Mintern, J.D.; Minucci, S.; Miranda-Vizuete, A.; Mitchell, C.H.; Miyamoto, S.; Miyazawa, K.; Mizushima, N.; Mnich, K.; Mograbi, B.; Mohseni, S.; Moita, L.F.; Molinari, M.; Molinari, M.; Møller, A.B.; Mollereau, B.; Mollinedo, F.; Mongillo, M.; Monick, M.M.; Montagnaro, S.; Montell, C.; Moore, D.J.; Moore, M.N.; Mora-Rodriguez, R.; Moreira, P.I.; Morel, E.; Morelli, M.B.; Moreno, S.; Morgan, M.J.; Moris, A.; Moriyasu, Y.; Morrison, J.L.; Morrison, L.A.; Morselli, E.; Moscat, J.; Moseley, P.L.; Mostowy, S.; Motori, E.; Mottet, D.; Mottram, J.C.; Moussa, C.E.H.; Mpakou, V.E.; Mukhtar, H.; Levy, J.M.M.; Muller, S.; Muñoz-Moreno, R.; Muñoz-Pinedo, C.; Münz, C.; Murphy, M.E.; Murray, J.T.; Murthy, A.; Mysorekar, I.U.; Nabi, I.R.; Nabissi, M.; Nader, G.A.; Nagahara, Y.; Nagai, Y.; Nagata, K.; Nagelkerke, A.; Nagy, P.; Naidu, S.R.; Nair, S.; Nakano, H.; Nakatogawa, H.; Nanjundan, M.; Napolitano, G.; Naqvi, N.I.; Nardacci, R.; Narendra, D.P.; Narita, M.; Nascimbeni, A.C.; Natarajan, R.; Navegantes, L.C.; Nawrocki, S.T.; Nazarko, T.Y.; Nazarko, V.Y.; Neill, T.; Neri, L.M.; Netea, M.G.; Netea-Maier, R.T.; Neves, B.M.; Ney, P.A.; Nezis, I.P.; Nguyen, H.T.T.; Nguyen, H.P.; Nicot, A.S.; Nilsen, H.; Nilsson, P.; Nishimura, M.; Nishino, I.; Niso-Santano, M.; Niu, H.; Nixon, R.A.; Njar, V.C.O.; Noda, T.; Noegel, A.A.; Nolte, E.M.; Norberg, E.; Norga, K.K.; Noureini, S.K.; Notomi, S.; Notterpek, L.; Nowikovsky, K.; Nukina, N.; Nürnberger, T.; O'donnell, V.B.; O'donovan, T.; O'dwyer, P.J.; Oehme, I.; Oeste, C.L.; Ogawa, M.; Ogretmen, B.; Ogura, Y.; Oh, Y.J.; Ohmuraya, M.; Ohshima, T.; Ojha, R.; Okamoto, K.; Okazaki, T.; Oliver, F.J.; Ollinger, K.; Olsson, S.; Orban, D.P.; Ordonez, P.; Orhon, I.; Orosz, L.; O'rourke, E.J.; Orozco, H.; Ortega, A.L.; Ortona, E.; Osellame, L.D.; Oshima, J.; Oshima, S.; Osiewacz, H.D.; Otomo, T.; Otsu, K.; Ou, J.H.J.; Outeiro, T.F.; Ouyang, D.Y.; Ouyang, H.; Overholtzer, M.; Ozbun, M.A.; Ozdinler, P.H.; Ozpolat, B.; Pacelli, C.; Paganetti, P.; Page, G.; Pages, G.; Pagnini, U.; Pajak, B.; Pak, S.C.; Pakos-Zebrucka, K.; Pakpour, N.; Palková, Z.; Palladino, F.; Pallauf, K.; Pallet, N.; Palmieri, M.; Paludan, S.R.; Palumbo, C.; Palumbo, S.; Pampliega, O.; Pan, H.; Pan, W.; Panaretakis, T.; Pandey, A.; Pantazopoulou, A.; Papackova, Z.; Papademetrio, D.L.; Papassideri, I.; Papini, A.; Parajuli, N.; Pardo, J.; Parekh, V.V.; Parenti, G.; Park, J.I.; Park, J.; Park, O.K.; Parker, R.; Parlato, R.; Parys, J.B.; Parzych, K.R.; Pasquet, J.M.; Pasquier, B.; Pasumarthi, K.B.S.; Patterson, C.; Pattingre, S.; Pattison, S.; Pause, A.; Pavenstädt, H.; Pavone, F.; Pedrozo, Z.; Peña, F.J.; Peñalva, M.A.; Pende, M.; Peng, J.; Penna, F.; Penninger, J.M.; Pensalfini, A.; Pepe, S.; Pereira, G.J.S.; Pereira, P.C.; de la Cruz, V.P.; Pérez-Pérez, M.E.; Pérez-Rodríguez, D.; Pérez-Sala, D.; Perier, C.; Perl, A.; Perlmutter, D.H.; Perrotta, I.; Pervaiz, S.; Pesonen, M.; Pessin, J.E.; Peters, G.J.; Petersen, M.; Petrache, I.; Petrof, B.J.; Petrovski, G.; Phang, J.M.; Piacentini, M.; Pierdominici, M.; Pierre, P.; Pierrefite-Carle, V.; Pietrocola, F.; Pimentel-Muiños, F.X.; Pinar, M.; Pineda, B.; Pinkas-Kramarski, R.; Pinti, M.; Pinton, P.; Piperdi, B.; Piret, J.M.; Platanias, L.C.; Platta, H.W.; Plowey, E.D.; Pöggeler, S.; Poirot, M.; Polčic, P.; Poletti, A.; Poon, A.H.; Popelka, H.; Popova, B.; Poprawa, I.; Poulose, S.M.; Poulton, J.; Powers, S.K.; Powers, T.; Pozuelo-Rubio, M.; Prak, K.; Prange, R.; Prescott, M.; Priault, M.; Prince, S.; Proia, R.L.; Proikas-Cezanne, T.; Prokisch, H.; Promponas, V.J.; Przyklenk, K.; Puertollano, R.; Pugazhenthi, S.; Puglielli, L.; Pujol, A.; Puyal, J.; Pyeon, D.; Qi, X.; Qian, W.B.; Qin, Z.H.; Qiu, Y.; Qu, Z.; Quadrilatero, J.; Quinn, F.; Raben, N.; Rabinowich, H.; Radogna, F.; Ragusa, M.J.; Rahmani, M.; Raina, K.; Ramanadham, S.; Ramesh, R.; Rami, A.; Randall-Demllo, S.; Randow, F.; Rao, H.; Rao, V.A.; Rasmussen, B.B.; Rasse, T.M.; Ratovitski, E.A.; Rautou, P.E.; Ray, S.K.; Razani, B.; Reed, B.H.; Reggiori, F.; Rehm, M.; Reichert, A.S.; Rein, T.; Reiner, D.J.; Reits, E.; Ren, J.; Ren, X.; Renna, M.; Reusch, J.E.B.; Revuelta, J.L.; Reyes, L.; Rezaie, A.R.; Richards, R.I.; Richardson, R.; Richetta, C.; Riehle, M.A.; Rihn, B.H.; Rikihisa, Y.; Riley, B.E.; Rimbach, G.; Rippo, M.R.; Ritis, K.; Rizzi, F.; Rizzo, E.; Roach, P.J.; Robbins, J.; Roberge, M.; Roca, G.; Roccheri, M.C.; Rocha, S.; Rodrigues, C.M.P.; Rodríguez, C.I.; De Córdoba, S.R.; Rodriguez-Muela, N.; Roelofs, J.; Rogov, V.V.; Rohn, T.T.; Rohrer, B.; Romanelli, D.; Romani, L.; Romano, P.S.; Roncero, M.I.G.; Rosa, J.L.; Rosello, A.; Rosen, K.V.; Rosenstiel, P.; Rost-Roszkowska, M.M.; Roth, K.A.; Roué, G.; Rouis, M.; Rouschop, K.M.A.; Ruan, D.T.; Ruano, D.; Rubinsztein, D.C.; Rucker, E.B.; Rudich, A.; Rudolf, E.; Rudolf, R.; Ruegg, M.A.; Ruiz-Roldan, C.; Ruparelia, A.A.; Rusmini, P.; Russ, D.W.; Russo, G.L.; Russo, G.; Russo, R.; Rusten, T.E.; Ryabovol, V.; Ryan, K.M.; Ryter, S.W.; Sabatini, D.M.; Sacher, M.; Sachse, C.; Sack, M.N.; Sadoshima, J.; Saftig, P.; Sagi-Eisenberg, R.; Sahni, S.; Saikumar, P.; Saito, T.; Saitoh, T.; Sakakura, K.; Sakoh-Nakatogawa, M.; Sakuraba, Y.; Salazar-Roa, M.; Salomoni, P.; Saluja, A.K.; Salvaterra, P.M.; Salvioli, R.; Samali, A.; Sanchez, A.M.J.; Sánchez-Alcázar, J.A.; Sánchez-Prieto, R.; Sandri, M.; Sanjuan, M.A.; Santaguida, S.; Santambrogio, L.; Santoni, G.; Dos Santos, C.N.; Saran, S.; Sardiello, M.; Sargent, G.; Sarkar, P.; Sarkar, S.; Sarrias, M.R.; Sarwal, M.M.; Sasakawa, C.; Sasaki, M.; Sass, M.; Sato, K.; Sato, M.; Satriano, J.; Savaraj, N.; Saveljeva, S.; Schaefer, L.; Schaible, U.E.; Scharl, M.; Schätzl, H.M.; Schekman, R.; Scheper, W.; Schiavi, A.; Schipper, H.M.; Schmeisser, H.; Schmidt, J.; Schmitz, I.; Schneider, B.E.; Schneider, E.M.; Schneider, J.L.; Schon, E.A.; Schönenberger, M.J.; Schönthal, A.H.; Schorderet, D.F.; Schröder, B.; Schuck, S.; Schulze, R.J.; Schwarten, M.; Schwarz, T.L.; Sciarretta, S.; Scotto, K.; Scovassi, A.I.; Screaton, R.A.; Screen, M.; Seca, H.; Sedej, S.; Segatori, L.; Segev, N.; Seglen, P.O.; Seguí-Simarro, J.M.; Segura-Aguilar, J.; Seiliez, I.; Seki, E.; Sell, C.; Semenkovich, C.F.; Semenza, G.L.; Sen, U.; Serra, A.L.; Serrano-Puebla, A.; Sesaki, H.; Setoguchi, T.; Settembre, C.; Shacka, J.J.; Shajahan-Haq, A.N.; Shapiro, I.M.; Sharma, S.; She, H.; Shen, C.K.J.; Shen, C.C.; Shen, H.M.; Shen, S.; Shen, W.; Sheng, R.; Sheng, X.; Sheng, Z.H.; Shepherd, T.G.; Shi, J.; Shi, Q.; Shi, Q.; Shi, Y.; Shibutani, S.; Shibuya, K.; Shidoji, Y.; Shieh, J.J.; Shih, C.M.; Shimada, Y.; Shimizu, S.; Shin, D.W.; Shinohara, M.L.; Shintani, M.; Shintani, T.; Shioi, T.; Shirabe, K.; Shiri-Sverdlov, R.; Shirihai, O.S.; Shore, G.C.; Shu, C.W.; Shukla, D.; Sibirny, A.A.; Sica, V.; Sigurdson, C.J.; Sigurdsson, E.M.; Sijwali, P.S.; Sikorska, B.; Silveira, W.A.; Silvente-Poirot, S.; Silverman, G.A.; Simak, J.; Simmet, T.; Simon, A.K.; Simon, H.U.; Simone, C.; Simons, M.; Simonsen, A.; Singh, R.; Singh, S.V.; Singh, S.K.; Sinha, D.; Sinha, S.; Sinicrope, F.A.; Sirko, A.; Sirohi, K.; Sishi, B.J.N.; Sittler, A.; Siu, P.M.; Sivridis, E.; Skwarska, A.; Slack, R.S.; Slaninová, I.; Slavov, N.; Smaili, S.S.; Smalley, K.S.M.; Smith, D.R.; Soenen, S.J.; Soleimanpour, S.A.; Solhaug, A.; Somasundaram, K.; Son, J.H.; Sonawane, A.; Song, C.; Song, F.; Song, H.K.; Song, J.X.; Song, W.; Soo, K.Y.; Sood, A.K.; Soong, T.W.; Soontornniyomkij, V.; Sorice, M.; Sotgia, F.; Soto-Pantoja, D.R.; Sotthibundhu, A.; Sousa, M.J.; Spaink, H.P.; Span, P.N.; Spang, A.; Sparks, J.D.; Speck, P.G.; Spector, S.A.; Spies, C.D.; Springer, W.; Clair, D.S.; Stacchiotti, A.; Staels, B.; Stang, M.T.; Starczynowski, D.T.; Starokadomskyy, P.; Steegborn, C.; Steele, J.W.; Stefanis, L.; Steffan, J.S.; Stellrecht, C.M.; Stenmark, H.; Stepkowski, T.M.; Stern, S.T.; Stevens, C.; Stockwell, B.R.; Stoka, V.; Storchova, Z.; Stork, B.; Stratoulias, V.; Stravopodis, D.J.; Strnad, P.; Strohecker, A.M.; Ström, A.L.; Stromhaug, P.; Stulik, J.; Su, Y.X.; Su, Z.; Subauste, C.S.; Subramaniam, S.; Sue, C.M.; Suh, S.W.; Sui, X.; Sukseree, S.; Sulzer, D.; Sun, F.L.; Sun, J.; Sun, J.; Sun, S.Y.; Sun, Y.; Sun, Y.; Sun, Y.; Sundaramoorthy, V.; Sung, J.J.Y.; Suzuki, H.; Suzuki, K.; Suzuki, N.; Suzuki, T.; Suzuki, Y.J.; Swanson, M.S.; Swanton, C.; Swärd, K.; Swarup, G.; Sweeney, S.T.; Sylvester, P.W.; Szatmari, Z.; Szegezdi, E.; Szlosarek, P.W.; Taegtmeyer, H.; Tafani, M.; Taillebourg, E.; Tait, S.W.G.; Takács-Vellai, K.; Takahashi, Y.; Takáts, S.; Takemura, G.; Takigawa, N.; Talbot, N.J.; Tamagno, E.; Tamburini, J.; Tan, C.P.; Tan, L.; Tan, M.L.; Tan, M.; Tan, Y.J.; Tanaka, K.; Tanaka, M.; Tang, D.; Tang, D.; Tang, G.; Tanida, I.; Tanji, K.; Tannous, B.A.; Tapia, J.A.; Tasset-Cuevas, I.; Tatar, M.; Tavassoly, I.; Tavernarakis, N.; Taylor, A.; Taylor, G.S.; Taylor, G.A.; Taylor, J.P.; Taylor, M.J.; Tchetina, E.V.; Tee, A.R.; Teixeira-Clerc, F.; Telang, S.; Tencomnao, T.; Teng, B.B.; Teng, R.J.; Terro, F.; Tettamanti, G.; Theiss, A.L.; Theron, A.E.; Thomas, K.J.; Thomé, M.P.; Thomes, P.G.; Thorburn, A.; Thorner, J.; Thum, T.; Thumm, M.; Thurston, T.L.M.; Tian, L.; Till, A.; Ting, J.P.Y.; Ting, J.P.Y.; Titorenko, V.I.; Toker, L.; Toldo, S.; Tooze, S.A.; Topisirovic, I.; Torgersen, M.L.; Torosantucci, L.; Torriglia, A.; Torrisi, M.R.; Tournier, C.; Towns, R.; Trajkovic, V.; Travassos, L.H.; Triola, G.; Tripathi, D.N.; Trisciuoglio, D.; Troncoso, R.; Trougakos, I.P.; Truttmann, A.C.; Tsai, K.J.; Tschan, M.P.; Tseng, Y.H.; Tsukuba, T.; Tsung, A.; Tsvetkov, A.S.; Tu, S.; Tuan, H.Y.; Tucci, M.; Tumbarello, D.A.; Turk, B.; Turk, V.; Turner, R.F.B.; Tveita, A.A.; Tyagi, S.C.; Ubukata, M.; Uchiyama, Y.; Udelnow, A.; Ueno, T.; Umekawa, M.; Umemiya-Shirafuji, R.; Underwood, B.R.; Ungermann, C.; Ureshino, R.P.; Ushioda, R.; Uversky, V.N.; Uzcátegui, N.L.; Vaccari, T.; Vaccaro, M.I.; Váchová, L.; Vakifahmetoglu-Norberg, H.; Valdor, R.; Valente, E.M.; Vallette, F.; Valverde, A.M.; Van den Berghe, G.; Van Den Bosch, L.; van den Brink, G.R.; van der Goot, F.G.; van der Klei, I.J.; van der Laan, L.J.W.; van Doorn, W.G.; van Egmond, M.; van Golen, K.L.; Van Kaer, L.; Campagne, M.L.; Vandenabeele, P.; Vandenberghe, W.P.; Vanhorebeek, I.; Varela-Nieto, I.; Vasconcelos, M.H.; Vasko, R.; Vavvas, D.G.; Vega-Naredo, I.; Velasco, G.; Velentzas, A.D.; Velentzas, P.D.; Vellai, T.; Vellenga, E.; Vendelbo, M.H.; Venkatachalam, K.; Ventura, N.; Ventura, S.; Veras, P.S.T.; Verdier, M.; Vertessy, B.G.; Viale, A.; Vidal, M.; Vieira, H.L.A.; Vierstra, R.D.; Vigneswaran, N.; Vij, N.; Vila, M.; Villar, M.; Villar, V.H.; Villarroya, J.; Vindis, C.; Viola, G.; Viscomi, M.T.; Vitale, G.; Vogl, D.T.; Voitsekhovskaja, O.V.; von Haefen, C.; von Schwarzenberg, K.; Voth, D.E.; Vouret-Craviari, V.; Vuori, K.; Vyas, J.M.; Waeber, C.; Walker, C.L.; Walker, M.J.; Walter, J.; Wan, L.; Wan, X.B.; Wang, B.; Wang, C.; Wang, C.Y.; Wang, C.; Wang, C.; Wang, C.; Wang, D.; Wang, F.; Wang, F.; Wang, G.; Wang, H.J.; Wang, H.; Wang, H.G.; Wang, H.; Wang, H.D.; Wang, J.; Wang, J.; Wang, M.; Wang, M.Q.; Wang, P.Y.; Wang, P.; Wang, R.C.; Wang, S.; Wang, T.F.; Wang, X.; Wang, X.J.; Wang, X.W.; Wang, X.; Wang, X.; Wang, Y.; Wang, Y.; Wang, Y.; Wang, Y.J.; Wang, Y.; Wang, Y.; Wang, Y.T.; Wang, Y.; Wang, Z.N.; Wappner, P.; Ward, C.; Ward, D.M.V.; Warnes, G.; Watada, H.; Watanabe, Y.; Watase, K.; Weaver, T.E.; Weekes, C.D.; Wei, J.; Weide, T.; Weihl, C.C.; Weindl, G.; Weis, S.N.; Wen, L.P.; Wen, X.; Wen, Y.; Westermann, B.; Weyand, C.M.; White, A.R.; White, E.; Whitton, J.L.; Whitworth, A.J.; Wiels, J.; Wild, F.; Wildenberg, M.E.; Wileman, T.; Wilkinson, D.S.; Wilkinson, S.; Willbold, D.; Williams, C.; Williams, K.; Williamson, P.R.; Winklhofer, K.F.; Witkin, S.S.; Wohlgemuth, S.E.; Wollert, T.; Wolvetang, E.J.; Wong, E.; Wong, G.W.; Wong, R.W.; Wong, V.K.W.; Woodcock, E.A.; Wright, K.L.; Wu, C.; Wu, D.; Wu, G.S.; Wu, J.; Wu, J.; Wu, M.; Wu, M.; Wu, S.; Wu, W.K.K.; Wu, Y.; Wu, Z.; Xavier, C.P.R.; Xavier, R.J.; Xia, G.X.; Xia, T.; Xia, W.; Xia, Y.; Xiao, H.; Xiao, J.; Xiao, S.; Xiao, W.; Xie, C.M.; Xie, Z.; Xie, Z.; Xilouri, M.; Xiong, Y.; Xu, C.; Xu, C.; Xu, F.; Xu, H.; Xu, H.; Xu, J.; Xu, J.; Xu, J.; Xu, L.; Xu, X.; Xu, Y.; Xu, Y.; Xu, Z.X.; Xu, Z.; Xue, Y.; Yamada, T.; Yamamoto, A.; Yamanaka, K.; Yamashina, S.; Yamashiro, S.; Yan, B.; Yan, B.; Yan, X.; Yan, Z.; Yanagi, Y.; Yang, D.S.; Yang, J.M.; Yang, L.; Yang, M.; Yang, P.M.; Yang, P.; Yang, Q.; Yang, W.; Yang, W.Y.; Yang, X.; Yang, Y.; Yang, Y.; Yang, Z.; Yang, Z.; Yao, M.C.; Yao, P.J.; Yao, X.; Yao, Z.; Yao, Z.; Yasui, L.S.; Ye, M.; Yedvobnick, B.; Yeganeh, B.; Yeh, E.S.; Yeyati, P.L.; Yi, F.; Yi, L.; Yin, X.M.; Yip, C.K.; Yoo, Y.M.; Yoo, Y.H.; Yoon, S.Y.; Yoshida, K.I.; Yoshimori, T.; Young, K.H.; Yu, H.; Yu, J.J.; Yu, J.T.; Yu, J.; Yu, L.; Yu, W.H.; Yu, X.F.; Yu, Z.; Yuan, J.; Yuan, Z.M.; Yue, B.Y.J.T.; Yue, J.; Yue, Z.; Zacks, D.N.; Zacksenhaus, E.; Zaffaroni, N.; Zaglia, T.; Zakeri, Z.; Zecchini, V.; Zeng, J.; Zeng, M.; Zeng, Q.; Zervos, A.S.; Zhang, D.D.; Zhang, F.; Zhang, G.; Zhang, G.C.; Zhang, H.; Zhang, H.; Zhang, H.; Zhang, J.; Zhang, J.; Zhang, J.; Zhang, J.P.; Zhang, L.; Zhang, L.; Zhang, L.; Zhang, M.Y.; Zhang, X.; Zhang, X.D.; Zhang, Y.; Zhang, Y.; Zhang, Y.; Zhang, Y.; Zhang, Y.; Zhao, M.; Zhao, W.L.; Zhao, X.; Zhao, Y.G.; Zhao, Y.; Zhao, Y.; Zhao, Y.X.; Zhao, Z.; Zhao, Z.J.; Zheng, D.; Zheng, X.L.; Zheng, X.; Zhivotovsky, B.; Zhong, Q.; Zhou, G.Z.; Zhou, G.; Zhou, H.; Zhou, S.F.; Zhou, X.J.; Zhu, H.; Zhu, H.; Zhu, W.G.; Zhu, W.; Zhu, X.F.; Zhu, Y.; Zhuang, S.M.; Zhuang, X.; Ziparo, E.; Zois, C.E.; Zoladek, T.; Zong, W.X.; Zorzano, A.; Zughaier, S.M.},

note = {20},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-84996587512,

title = {Body cavity cells of Parachela during their active life},

author = { M. Hyra and M.M. Rost-Roszkowska and S. Student and A. Włodarczyk and M. Deperas and K. Janelt and I. Poprawa},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84996587512&doi=10.1111%2fzoj.12463&partnerID=40&md5=350576eb88cfb1a39add6b3a09711fd1},

doi = {10.1111/zoj.12463},

issn = {00244082},

year  = {2016},

date = {2016-01-01},

journal = {Zoological Journal of the Linnean Society},

volume = {178},

number = {4},

pages = {878-887},

publisher = {Blackwell Publishing Ltd},

abstract = {The body cavity cells (storage cells; storage bodies) of four species of Parachela (hermaphroditic Isohypsibius granulifer granulifer; parthenogenetic Hypsibius dujardini; gonochoristic Xerobiotus pseudohufelandi; gonochoristic Macrobiotus polonicus) were analysed during their active life using light, confocal (laser scanning), and scanning and transmission electron microscopy. The ultrastructure of the storage cells confirmed previous studies suggesting a high level of metabolic activity. Additionally, we revealed the participation of the storage cells of H. dujardini, I. g. granulifer, and M. polonicus in the synthesis of vitellogenins. This did not seem to apply for X. pseudohufelandi. All of the species that were examined in this study accumulated polysaccharides, proteins, and lipids in their body cavity cells, but the amount of these components differed in each species. Isohypsibius g. granulifer accumulated a huge amount of polysaccharides and smaller amounts of lipids and proteins, H. dujardini and M. polonicus primarily accumulated lipids and small amounts of polysaccharides and proteins, whereas X. pseudohufelandi primarily accumulated polysaccharides and lipids, and a small amount of proteins. © 2016 The Linnean Society of London},

note = {11},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-84996587380,

title = {Ultrastructural changes in the midgut epithelium of Hypsibius dujardini (Doyère, 1840) (Tardigrada, Eutardigrada, Hypsibiidae) in relation to oogenesis},

author = { M. Hyra and I. Poprawa and A. Włodarczyk and S. Student and L. Sonakowska and M. Kszuk-Jendrysik and M.M. Rost-Roszkowska},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84996587380&doi=10.1111%2fzoj.12467&partnerID=40&md5=b97a5818640cb0b994faeef9aad17b1d},

doi = {10.1111/zoj.12467},

issn = {00244082},

year  = {2016},

date = {2016-01-01},

journal = {Zoological Journal of the Linnean Society},

volume = {178},

number = {4},

pages = {897-906},

publisher = {Blackwell Publishing Ltd},

abstract = {In Hypsibius dujardini (Doyère; 1840), the endodermal region of the digestive system, which is called the midgut, spreads along the entire length of the body. Its wall is formed by a simple epithelium that is composed of digestive cells. In this paper, we present the first report on the presence of two groups of midgut regenerative cells that form two ‘epithelial rings’ – anterior and posterior. Additionally, we observed the proliferative abilities of the midgut regenerative cells, thus confirming the statement that they play the role of midgut stem cells. The precise ultrastructure of the digestive and regenerative cells was determined using transmission electron microscopy. Changes in the digestive and regenerative cells were correlated with the different stages of oogenesis. The process of oogenesis in H. dujardini took 4 days (at a temperature of 16 °C). Reserve material gradually accumulated in the cytoplasm of the digestive cells and histochemical staining showed that it primarily contained proteins, polysaccharides and a small quantity of lipids. The reserve material accumulated during vitellogenesis, and it began to decrease during choriogenesis. During the simplex stage, when the entire buccal–pharyngeal apparatus was expelled from the body, the stages of oogenesis were advanced, the midgut was much reduced, and the reserve material was exploited by the animal. © 2016 The Linnean Society of London},

note = {19},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-84988967346,

title = {Effects of short-term exposure of Acheta domesticus to nanodiamonds in food: DNA damage but no histological alteration in tissues},

author = { J. Karpeta-Kaczmarek and M. Dziewięcka and M. Augustyniak and M.M. Rost-Roszkowska},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84988967346&doi=10.1016%2fj.carbon.2016.09.053&partnerID=40&md5=d32e762f3268d893f2f64f4d52fc9f33},

doi = {10.1016/j.carbon.2016.09.053},

issn = {00086223},

year  = {2016},

date = {2016-01-01},

journal = {Carbon},

volume = {110},

pages = {458-468},

publisher = {Elsevier Ltd},

abstract = {The aim of this work is to evaluate toxicity of nanodiamonds (ND; 20 and 200 mg g−1 food) to Acheta domesticus after short-term exposure (10 days) in food. Catalase (CAT), total antioxidant capacity (TAC), stress protein level (HSP70) and DNA damage to hemocytes were monitored every two days. On day 2 and 10, the levels of reactive oxygen species (ROS), apoptosis (annexin V and multicaspase tests), cell cycle and DNA damage to the gut were examined. The ultrastructure of the gut epithelium and testis was assessed on day 10 of the experiment. CAT, TAC, HSP70 in hemolymph, and histological morphology of gut and testis did not indicate ND toxicity. In the gut we observed a transient increase in CAT activity on day 2,4 and 6; and an increase in HSP70 level on day 6, 8 and 10. TAC level in the gut did not increase until day 10. ND did not influence ROS level in cells and the cell cycle. Yet, we observed a moderate increase in apoptosis, particularly at the higher ND concentration. ND induced dose-dependent DNA damage. We can conclude that short-term, occasional exposure to trace amounts of ND, like in medical applications, is probably safe for organisms. © 2016 Elsevier Ltd},

note = {10},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-84992337575,

title = {Ultrastructure of the salivary glands in Lithobius forficatus (Myriapoda, Chilopoda, Lithobiidae) according to seasonal and circadian rhythms},

author = { K. Kamińska and A. Włodarczyk and L. Sonakowska and A. Ostróżka and A. Marchewka and M.M. Rost-Roszkowska},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84992337575&doi=10.1016%2fj.asd.2016.09.007&partnerID=40&md5=6f6c2614ddf19d4668828754d91e46c1},

doi = {10.1016/j.asd.2016.09.007},

issn = {14678039},

year  = {2016},

date = {2016-01-01},

journal = {Arthropod Structure and Development},

volume = {45},

number = {6},

pages = {536-551},

publisher = {Elsevier Ltd},

abstract = {The salivary glands (mandibular epidermal glands) of adult males and females of Lithobius forficatus (Myriapoda; Chilopoda) were isolated during spring, summer and autumn. In addition, the organs were isolated at different times of the day – at about 12:00 (noon) and about 00:00 (midnight). The ultrastructure of these organs depending on seasonal and circadian rhythms was analyzed using transmission and scanning electron microscopy and histochemical methods. The paired salivary glands of L. forficatus are situated in the vicinity of the foregut and they are formed by numerous acini that are surrounded by the fat body, hemocytes and tracheolae. The salivary glands are composed of a terminal acinar component and a system of tubular ducts that are lined with a cuticle. The glandular part is composed of secretory epithelial cells that are at various stages of their secretory activity. The saliva that is produced by the secretory cells of the acini is secreted into the salivary ducts, which are lined with a simple epithelium that is based on the non-cellular basal lamina. The ultrastructural variations suggest that salivary glands function differently depending on seasonal rhythms and prepare the animal for overwintering. Therefore, the salivary glands of the centipedes that were analyzed participate in the accumulation of proteins, lipids and polysaccharides during the spring, summer and autumn. Subtle differences in the ultrastructure of the secretory cells of the salivary glands during the circadian cycle must be related to the physiological reactions of the organism. The salivary ducts showed no differences in the specimens that were analyzed during the day/night cycle or during the seasonal cycle. © 2016 Elsevier Ltd},

note = {5},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-85009155963,

title = {Oxidative stress and genotoxic effects of diamond nanoparticles},

author = { J. Karpeta-Kaczmarek and M. Dziewięcka and M. Augustyniak and M.M. Rost-Roszkowska and M. Pawlyta},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85009155963&doi=10.1016%2fj.envres.2016.03.033&partnerID=40&md5=bfdeb3e3583c5cd2075827dc02e209e2},

doi = {10.1016/j.envres.2016.03.033},

issn = {00139351},

year  = {2016},

date = {2016-01-01},

journal = {Environmental Research},

volume = {148},

pages = {264-272},

publisher = {Academic Press Inc.},

abstract = {Due to the unique and useful properties of nanodiamonds (ND), their production and use is rapidly increasing. Thus, more of these particles will be released into the environment and organisms will inevitably be exposed to them. The current knowledge about the toxicity of ND, especially in vivo toxicity, is fragmentary. In this study, the toxicity of nanodiamonds was assessed in Acheta domesticus following chronic exposure to different nominal concentrations of ND (20 and 200 µg g−1 food) administrated in food for the entire lifespan. The activity of oxidative stress enzymes (catalase; glutathione peroxidase), total antioxidant capacity, as well as the level of heat shock protein were determined. A significant increase in all of the measured parameters was observed after seven weeks of exposure in individuals exposed to higher concentrations of ND (200 µg g−1 food). In animals exposed to lower concentrations of ND (20 µg g−1 food), there were few significant changes to these parameters. Analysis of DNA damage performed after fourteen weeks using the comet assay revealed DNA instabilities in the insects, especially the ones that had been exposed to the higher doses of ND. These findings may suggest that the toxicity of ND is concentration dependent. While high doses interact in a toxic manner, trace amounts, which are more likely in the environment, might be safe for organisms. Extreme caution should be taken when handling nanodiamonds. © 2016 Elsevier Inc.},

note = {25},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-84939224040,

title = {Apoptosis and necrosis during the circadian cycle in the centipede midgut},

author = { M.M. Rost-Roszkowska and Ł. Chajec and J. Vilimová and K. Tajovský},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84939224040&doi=10.1007%2fs00709-015-0864-8&partnerID=40&md5=848e60189ffaad598a41ed16df2e8f7c},

doi = {10.1007/s00709-015-0864-8},

issn = {0033183X},

year  = {2016},

date = {2016-01-01},

journal = {Protoplasma},

volume = {253},

number = {4},

pages = {1051-1061},

publisher = {Springer-Verlag Wien},

abstract = {Three types of cells have been distinguished in the midgut epithelium of two centipedes, Lithobius forficatus and Scolopendra cingulata: digestive, secretory, and regenerative cells. According to the results of our previous studies, we decided to analyze the relationship between apoptosis and necrosis in their midgut epithelium and circadian rhythms. Ultrastructural analysis showed that these processes proceed in a continuous manner that is independent of the circadian rhythm in L. forficatus, while in S. cingulata necrosis is activated at midnight. Additionally, the description of apoptosis and necrosis showed no differences between males and females of both species analyzed. At the beginning of apoptosis, the cell cytoplasm becomes electron-dense, apparently in response to shrinkage of the cell. Organelles such as the mitochondria, cisterns of endoplasmic reticulum transform and degenerate. Nuclei gradually assume lobular shapes before the apoptotic cell is discharged into the midgut lumen. During necrosis, however, the cytoplasm of the cell becomes electron-lucent, and the number of organelles decreases. While the digestive cells of about 10 % of L. forficatus contain rickettsia-like pathogens, the corresponding cells in S. cingulata are free of rickettsia. As a result, we can state that apoptosis in L. forficatus is presumably responsible for protecting the organism against infections, while in S. cingulata apoptosis is not associated with the elimination of pathogens. Necrosis is attributed to mechanical damage, and the activation of this process coincides with proliferation of the midgut regenerative cells at midnight in S. cingulata. © 2015, Springer-Verlag Wien.},

note = {9},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-84960146447,

title = {Ultrastructure of the gut epithelium in Acheta domesticus after long-term exposure to nanodiamonds supplied with food},

author = { J. Karpeta-Kaczmarek and M. Augustyniak and M.M. Rost-Roszkowska},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84960146447&doi=10.1016%2fj.asd.2016.02.002&partnerID=40&md5=b823973c49c0d6eb90b51665238d44bc},

doi = {10.1016/j.asd.2016.02.002},

issn = {14678039},

year  = {2016},

date = {2016-01-01},

journal = {Arthropod Structure and Development},

volume = {45},

number = {3},

pages = {253-264},

publisher = {Elsevier Ltd},

abstract = {The biosafety of nanoparticles and the potential toxicity of nanopollutants and/or nanowastes are all currently burning issues. The increased use of nanoparticles, including nanodiamonds (ND), entails the real risk of their penetration into food chains, which may result in the contamination of animal and, as a result, human food. Knowledge about changes in the ultrastructure of tissues in organisms that have been exposed to ND is still very limited. The aim of the study was to describe the ultrastructure of the gut epithelium in Acheta domesticus after exposure to different concentrations of ND (0; 20 or 200 μg g-1 - control; ND20 and ND200 groups; respectively) administered with food over a five-week period. The ultrastructure of the foregut, midgut and hindgut was assessed using Transmission Electron Microscopy (TEM). A number of changes in the structure of the gut in crickets that had consumed nanodiamond-contaminated food were observed. The epithelium of the midgut and hindgut were clearly damaged by ND, although the foregut was not affected. A positive relationship between the ND concentration in food and the degree of damage to the structure of epithelial cells was observed. Autophagy, especially mitophagy and reticulophagy, was activated in relation to the appearance of ND particles. A putative ND toxicity mechanizm is proposed. Extreme caution should be maintained when using nanodiamonds on a large scale. © 2016 Elsevier Ltd.},

note = {24},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-84958825100,

title = {Cell Death in the Epithelia of the Intestine and Hepatopancreas in Neocaridina heteropoda (Crustacea, Malacostraca)},

author = { L. Sonakowska and A. Włodarczyk and G. Wilczek and P. Wilczek and S. Student and M.M. Rost-Roszkowska},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84958825100&doi=10.1371%2fjournal.pone.0147582&partnerID=40&md5=0c090df410aaa2984d12af4432ce4d17},

doi = {10.1371/journal.pone.0147582},

issn = {19326203},

year  = {2016},

date = {2016-01-01},

journal = {PLoS ONE},

volume = {11},

number = {2},

publisher = {Public Library of Science},

abstract = {The endodermal region of the digestive system in the freshwater shrimp Neocaridina heteropoda (Crustacea; Malacostraca) consists of a tube-shaped intestine and large hepatopancreas, which is formed by numerous blind-ended tubules. The precise structure and ultrastructure of these regions were presented in our previous studies, while here we focused on the cell death processes and their effect on the functioning of the midgut. We used transmission electron microscopy, light and confocal microscopes to describe and detect cell death, while a quantitative assessment of cells with depolarized mitochondria helped us to establish whether there is the relationship between cell death and the inactivation of mitochondria. Three types of the cell death were observed in the intestine and hepatopancreas- apoptosis, necrosis and autophagy. No differences were observed in the course of these processes in males and females and or in the intestine and hepatopancreas of the shrimp that were examined. Our studies revealed that apoptosis, necrosis and autophagy only involves the fully developed cells of the midgut epithelium that have contact with the midgut lumen-D-cells in the intestine and B- and F-cells in hepatopancreas, while E-cells (midgut stem cells) did not die. A distinct correlation between the accumulation of Ecells and the activation of apoptosis was detected in the anterior region of the intestine, while necrosis was an accidental process. Degenerating organelles, mainly mitochondria were neutralized and eventually, the activation of cell death was prevented in the entire epithelium due to autophagy. Therefore, we state that autophagy plays a role of the survival factor. © 2016 Sonakowska et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.},

note = {28},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{nokey,

title = {Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)},

author = { I. Poprawa and M.M. Rost-Roszkowska and D.J. Klionsky and K. Abdelmohsen and A. Abe and M.J. Abedin and H. Abeliovich and A. Acevedo-Arozena and H. Adachi and C.M. Adams and P.D. Adams and K. Adeli and P.J. Adhihetty and S.G. Adler and G. Agam and R. Agarwal and M.K. Aghi and M. Agnello and P. Agostinis and P.V. Aguilar and J.A. Aguirre-Ghiso and E.M. Airoldi and S. Ait-Si-Ali and T. Akematsu and E.T. Akporiaye and M. Al-Rubeai and G.M. Albaiceta and C. Albanese and D. Albani and M.L. Albert and J. Aldudo and H. Algül and M. Alirezaei and I. Alloza and A. Almasan and M. Almonte-Beceril and E.S. Alnemri and C. Alonso and N. Altan-Bonnet and D.C. Altieri and S. Alvarez and L. Alvarez-Erviti and S. Alves and G. Amadoro and A. Amano and C. Amantini and S. Ambrosio and I. Amelio and A.O. Amer and M. Amessou and A. Amon and Z. An and Authors. Other},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85013763791&doi=10.1080%2f15548627.2015.1100356&partnerID=40&md5=c7b9c89e5113f0c72d642ba75e5097c9},

doi = {10.1080/15548627.2015.1100356},

year  = {2016},

date = {2016-01-01},

journal = {Autophagy},

volume = {12},

number = {1},

pages = {1-222},

note = {3902},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{nokey,

title = {Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356},

author = { I. Poprawa and M.M. Rost-Roszkowska and D.J. Klionsky and K. Abdelmohsen and A. Abe and M.J. Abedin and H. Abeliovich and A. Acevedo-Arozena and H. Adachi and C.M. Adams and P.D. Adams and K. Adeli and P.J. Adhihetty and S.G. Adler and G. Agam and R. Agarwal and M.K. Aghi and M. Agnello and P. Agostinis and P.V. Aguilar and J.A. Aguirre-Ghiso and E.M. Airoldi and S. Ait-Si-Ali and T. Akematsu and E.T. Akporiaye and M. Al-Rubeai and G.M. Albaiceta and C. Albanese and D. Albani and M.L. Albert and J. Aldudo and H. Algül and M. Alirezaei and I. Alloza and A. Almasan and M. Almonte-Beceril and E.S. Alnemri and C. Alonso and N. Altan-Bonnet and D.C. Altieri and S. Alvarez and L. Alvarez-Erviti and S. Alves and G. Amadoro and A. Amano and C. Amantini and S. Ambrosio and I. Amelio and A.O. Amer and M. Amessou and A. Amon and Z. An and Authors. Other},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85054826264&doi=10.1080%2f15548627.2016.1147886&partnerID=40&md5=14fd1b79eff1a7ce4a3f523f1da1853d},

doi = {10.1080/15548627.2016.1147886},

year  = {2016},

date = {2016-01-01},

journal = {Autophagy},

volume = {12},

number = {2},

pages = {443-},

note = {20},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-84941261199,

title = {Ultrastructural analysis of apoptosis and autophagy in the midgut epithelium of Piscicola geometra (Annelida, Hirudinida) after blood feeding},

author = { M.M. Rost-Roszkowska and P. Świątek and I. Poprawa and W. Rupik and E. Swadźba and M. Kszuk-Jendrysik},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84941261199&doi=10.1007%2fs00709-015-0774-9&partnerID=40&md5=d95bf7417e87113a7f5110757a8a41ef},

doi = {10.1007/s00709-015-0774-9},

issn = {0033183X},

year  = {2015},

date = {2015-01-01},

journal = {Protoplasma},

volume = {252},

number = {5},

pages = {1387-1396},

publisher = {Springer-Verlag Wien},

abstract = {Cell death in the endodermal region of the digestive tract of the blood-feeding leech Piscicola geometra was analyzed using light and transmission electron microscopes and the fluorescence method. Sexually mature specimens of P. geometra were bred under laboratory conditions and fed on Danio rerio. After copulation, the specimens laid cocoons. The material for our studies were non-feeding juveniles collected just after hatching, non-feeding adult specimens, and leeches that had been fed with fish blood (D. rerio) only once ad libitum. The fed leeches were prepared for our studies during feeding and after 1, 3, 7, and 14 days (not sexually mature specimens) and some weeks after feeding (the sexually mature). Autophagy in all regions of the endodermal part of the digestive system, including the esophagus, the crop, the posterior crop caecum (PCC), and the intestine was observed in the adult non-feeding and feeding specimens. In fed specimens, autophagy occurred at very high levels—in 80 to 90 % of epithelial cells in all four regions. In contrast, in adult specimens that did not feed, this process occurred at much lower levels—about 10 % (esophagus and intestine) and about 30 % (crop and PCC) of the midgut epithelial cells. Apoptosis occurred in the feeding adult specimens but only in the crop and PCC. However, it was absent in the non-feeding adult specimens and the specimens that were collected during feeding. Moreover, neither autophagy nor apoptosis were observed in the juvenile, non-feeding specimens. The appearance of autophagy and apoptosis was connected with feeding on toxic blood. We concluded that autophagy played the role of a survival factor and was involved in the protection of the epithelium against the products of blood digestion. Quantitative analysis was prepared to determine the number of autophagic and apoptotic cells. © 2015, The Author(s).},

note = {7},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-84943450004,

title = {Germ cell cluster organization and oogenesis in the tardigrade dactylobiotus parthenogeneticus bertolani, 1982 (Eutardigrada, murrayidae)},

author = { I. Poprawa and M. Hyra and M.M. Rost-Roszkowska},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84943450004&doi=10.1007%2fs00709-014-0737-6&partnerID=40&md5=74609c7d317551c9790963b1a94ca4b1},

doi = {10.1007/s00709-014-0737-6},

issn = {0033183X},

year  = {2015},

date = {2015-01-01},

journal = {Protoplasma},

volume = {252},

number = {4},

pages = {1019-1029},

publisher = {Springer-Verlag Wien},

abstract = {Germ cell cluster organization and the process of oogenesis in Dactylobiotus parthenogeneticus have been described using transmission electron microscopy and light microscopy. The reproductive system of D. parthenogeneticus is composed of a single, sac-like, meroistic ovary and a single oviduct that opens into the cloaca. Two zones can be distinguished in the ovary: a small germarium that is filled with oogonia and a vitellarium that is filled with germ cell clusters. The germ cell cluster, which has the form of a modified rosette, consists of eight cells that are interconnected by stable cytoplasmic bridges. The cell that has the highest number of stable cytoplasmic bridges (four bridges) finally develops into the oocyte, while the remaining cells become trophocytes. Vitellogenesis of amixed type occurs in D. parthenogeneticus. One part of the yolk material is produced inside the oocyte (autosynthesis), while the second part is synthesized in the trophocytes and transported to the oocyte through the cytoplasmic bridges. The eggs are covered with two envelopes: a thin vitelline envelope and a three-layered chorion. The surface of the chorion forms small conical processes, the shape of which is characteristic for the species that was examined. In our paper, we present the first report on the rosette type of germ cell clusters in Parachela. © 2014, Springer-Verlag.},

note = {29},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-84930651291,

title = {Structure and ultrastructure of the endodermal region of the alimentary tract in the freshwater shrimp Neocaridina heteropoda (Crustacea, Malacostraca)},

author = { L. Sonakowska and A. Włodarczyk and I. Poprawa and M. Binkowski and J. ͆róbka and K. Kamińska and M. Kszuk-Jendrysik and Ł. Chajec and B. Zajusz and M.M. Rost-Roszkowska},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84930651291&doi=10.1371%2fjournal.pone.0126900&partnerID=40&md5=35407371799f653f6f724110b7a59dbe},

doi = {10.1371/journal.pone.0126900},

issn = {19326203},

year  = {2015},

date = {2015-01-01},

journal = {PLoS ONE},

volume = {10},

number = {5},

publisher = {Public Library of Science},

abstract = {The freshwater shrimp Neocaridina heteropoda (Crustacea; Malacostraca; Decapoda) originates from Asia and is one of the species that is widely available all over the world because it is the most popular shrimp that is bred in aquaria. The structure and the ultrastructure of the midgut have been described using X-ray microtomography, transmission electron microscopy, light and fluorescence microscopes. The endodermal region of the alimentary system in N. heteropoda consists of an intestine and a hepatopancreas. No differences were observed in the structure and ultrastructure of males and females of the shrimp that were examined. The intestine is a tube-shaped organ and the hepatopancreas is composed of two large diverticles that are divided into the blind-end tubules. Hepatopancreatic tubules have three distinct zones - proximal, medial and distal. Among the epithelial cells of the intestine, two types of cells were distinguished - D and E-cells, while three types of cells were observed in the epithelium of the hepatopancreas - F, B and E-cells. Our studies showed that the regionalization in the activity of cells occurs along the length of the hepatopancreatic tubules. The role and ultrastructure of all types of epithelial cells are discussed, with the special emphasis on the function of the E-cells, which are the midgut regenerative cells. Additionally, we present the first report on the existence of an intercellular junction that is connected with the E-cells of Crustacea. © 2015 Sonakowska et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.},

note = {25},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-84919935962,

title = {Ultrastructural changes and programmed cell death of trophocytes in the gonad of Isohypsibius granulifer granulifer Thulin, 1928 (Tardigrada, Eutardigrada, Isohypsibiidae)},

author = { I. Poprawa and M. Hyra and M. Kszuk-Jendrysik and M.M. Rost-Roszkowska},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84919935962&doi=10.1016%2fj.micron.2014.11.008&partnerID=40&md5=8991e963db8aff5e58cf49caf7bdfcbf},

doi = {10.1016/j.micron.2014.11.008},

issn = {09684328},

year  = {2015},

date = {2015-01-01},

journal = {Micron},

volume = {70},

pages = {26-33},

publisher = {Elsevier Ltd},

abstract = {The studies on the fates of the trophocytes, the apoptosis and autophagy in the gonad of Isohypsibius granulifer granulifer have been described using transmission electron microscope, light and fluorescent microscopes. The results presented here are the first that are connected with the cell death of nurse cells in the gonad of tardigrades. However, here we complete the results presented by Weglarska (1987). The reproductive system of I. g. granulifer contains a single sack-like hermaphroditic gonad and a single gonoduct. The gonad is composed of three parts: a germarium filled with proliferating germ cells (oogonia); a vitellarium that has clusters of female germ cells (the region of oocytes development); and a male part filled with male germ cells in which the sperm cells develop. The trophocytes (nurse cells) show distinct alterations during all of the stages of oogenesis: previtello-, vitello- and choriogenesis. During previtellogenesis the female germ cells situated in the vitellarium are connected by cytoplasmic bridges, and form clusters of cells. No ultrastructural differences appear among the germ cells in a cluster during this stage of oogenesis. In early vitellogenesis, the cells in each cluster start to grow and numerous organelles gradually accumulate in their cytoplasm. However, at the beginning of the middle of vitellogenesis, one cell in each cluster starts to grow in order to differentiate into oocyte, while the remaining cells are trophocytes. Eventually, the cytoplasmic bridges between the oocyte and trophocytes disappear. Autophagosomes also appear in the cytoplasm of nurse cells together with many degenerating organelles. The cytoplasm starts to shrink, which causes the degeneration of the cytoplasmic bridges between trophocytes. Apoptosis begins when the cytoplasm of these cells is full of autophagosomes/autolysosomes and causes their death. © 2014 Elsevier Ltd.},

note = {17},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-84911951699,

title = {Ultrastructural studies on the midgut of biting midge Forcipomyia nigra (Winnertz) (Diptera: Ceratopogonidae)},

author = { A. Urbanek and M.M. Rost-Roszkowska},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84911951699&doi=10.1016%2fj.micron.2014.11.003&partnerID=40&md5=ebebdf2c3deef872da187870128686b0},

doi = {10.1016/j.micron.2014.11.003},

issn = {09684328},

year  = {2015},

date = {2015-01-01},

journal = {Micron},

volume = {69},

pages = {25-34},

publisher = {Elsevier Ltd},

abstract = {Biting midges belonging to the genus Forcipomyia are known to be hematophagous, predatory or saprophagous. Different stages of Forcipomyia nigra midges were investigated to provide a description of midgut ultrastructure. Larvae feeding on decaying organic matter possess simple, straight alimentary tracts whose middle regions are the longest. TEM studies of the larval midgut epithelium reveal that digestive cells show different ultrastructure depending on their age. The older cells with electron-dense cytoplasm degenerate while the younger ones with electron-lucent cytoplasm remain active in digestion. In saprophagous females, the ultrastructure of midgut epithelium changes according to the age of flies. Oogenesis induces degeneration of digestive cells and utilization of reserve material accumulated by them. The midgut epithelia of male midges consist of digestive and regenerative cells that show no evidence of cell degeneration as observed in females. Our results demonstrate differences between midgut digestive cells of males and females. © 2014 Elsevier Ltd.},

note = {6},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-84944458224,

title = {Does autophagy in the midgut epithelium of centipedes depend on the day/night cycle?},

author = { M.M. Rost-Roszkowska and Ł. Chajec and J. Vilimová and K. Tajovský and M. Kszuk-Jendrysik},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84944458224&doi=10.1016%2fj.micron.2014.10.003&partnerID=40&md5=121ae07d2f9f942845b0ecd3f97f2a27},

doi = {10.1016/j.micron.2014.10.003},

issn = {09684328},

year  = {2015},

date = {2015-01-01},

journal = {Micron},

volume = {68},

pages = {130-139},

publisher = {Elsevier Ltd},

abstract = {The midgut epithelium of two centipedes, Lithobius forficatus and Scolopendra cingulata, is composed of digestive, secretory and regenerative cells. In L. forficatus, the autophagy occurred only in the cytoplasm of the digestive cells as a sporadic process, while in S. cingulata, it occurred intensively in the digestive, secretory and regenerative cells of the midgut epithelium. In both of the species that were analyzed, this process proceeded in a continuous manner and did not depend on the day/night cycle. Ultrastructural analysis showed that the autophagosomes and autolysosomes were located mainly in the apical and perinuclear cytoplasm of the digestive cells in L. forficatus. However, in S. cingulata, the entire cytoplasm was filled with autophagosomes and autolysosomes. Initially the membranes of phagophores surround organelles during autophagosome formation. Autolysosomes result from the fusion of autophagosomes and lysosomes. Residual bodies which are the last stage of autophagy were released into the midgut lumen due to necrosis. Autophagy in the midgut epithelia that were analyzed was confirmed using acid phosphatase and mono-dansyl-cadaverine stainings. © 2014 Elsevier Ltd.},

note = {14},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-84907279007,

title = {Plant stem cells as innovation in cosmetics},

author = { M. Morus̈ and M. Baran and M.M. Rost-Roszkowska and U. Skotnicka-Graca},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84907279007&partnerID=40&md5=0f06fbda50dbcf0be0c1300956ff7b1e},

issn = {00016837},

year  = {2014},

date = {2014-01-01},

journal = {Acta Poloniae Pharmaceutica - Drug Research},

volume = {71},

number = {5},

pages = {701-707},

publisher = {Polish Pharmaceutical Society},

abstract = {The stem cells thanks to their ability of unlimited division number or transformation into different cell types creating organs, are responsible for regeneration processes. Depending on the organism in which the stem cells exists, they divide to the plant or animal ones. The later group includes the stem cells existing in both embryo's and adult human's organs. It includes, among others, epidermal stem cells, located in the hair follicle relieves and also in its basal layers, and responsible for permanent regeneration of the epidermis. Temporary science looks for method suitable for stimulation of the epidermis stem cells, amongst the other by delivery of e.g., growth factors for proliferation that decrease with the age. One of the methods is the use of the plant cell culture technology, including a number of methods that should ensure growth of plant cells, issues or organs in the environment with the microorganism-free medium. It uses abilities of the different plant cells to dedifferentiation into stem cells and coming back to the pluripotent status. The extracts obtained this way from the plant stem cells are currently used for production of both common or professional care cosmetics. This work describes exactly impact of the plant stem cell extract, coming from one type of the common apple tree (Uttwiler Spátlauber) to human skin as one of the first plant sorts, which are used in cosmetology and esthetic dermatology. © 2014, Polish Pharmaceutical Society. All rights reserved.},

note = {24},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-84893176120,

title = {Apoptotic and necrotic changes in the midgut glands of the wolf spider Xerolycosa nemoralis (Lycosidae) in response to starvation and dimethoate exposure},

author = { G. Wilczek and M.M. Rost-Roszkowska and P. Wilczek and A. Babczyńska and E. Szulińska and L. Sonakowska and M. Marek-Swedzioł},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84893176120&doi=10.1016%2fj.ecoenv.2013.09.034&partnerID=40&md5=b3fbd74af84e674bc32ed8f57abf0e60},

doi = {10.1016/j.ecoenv.2013.09.034},

issn = {01476513},

year  = {2014},

date = {2014-01-01},

journal = {Ecotoxicology and Environmental Safety},

volume = {101},

number = {1},

pages = {157-167},

abstract = {In the present study, the intensity of degenerative changes (apoptosis; necrosis) in the cells of the midgut glands of male and female wolf spiders, Xerolycosa nemoralis (Lycosidae), exposed to natural (starvation) and anthropogenic (the organophosphorous pesticide dimethoate) stressors under laboratory conditions were compared. The spiders were collected from two differentially polluted sites, both located in southern Poland: Katowice-Welnowiec, which is heavily polluted with metals, and Pilica, the reference site. Starvation and dimethoate treatment resulted in enhancement of apoptotic and necrotic changes in the midgut glands of the spiders. The frequency of degenerative changes in starving individuals was twice as high as in the specimens intoxicated with dimethoate. The percentage of apoptotic and necrotic cells was higher in starving males than in starving females. A high intensity of necrotic changes, together with increased Cas-3 like activity and a greater percentage of cells with depolarized mitochondria, were typical of starving males from the polluted site. The cell death indices observed in females depended more strongly on the type of stressor than on previous preexposure to pollutants. © 2013 Elsevier Inc.},

note = {28},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-84923205361,

title = {The ultrastructure of the midgut epithelium in millipedes (Myriapoda, Diplopoda)},

author = { A. Sosinka and M.M. Rost-Roszkowska and J. Vilimová and K. Tajovský and M. Kszuk-Jendrysik and Ł. Chajec and L. Sonakowska and K. Kamińska and M. Hyra and I. Poprawa},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84923205361&doi=10.1016%2fj.asd.2014.06.005&partnerID=40&md5=031bc4c9e5c7c026a821e76da1ca47ce},

doi = {10.1016/j.asd.2014.06.005},

issn = {14678039},

year  = {2014},

date = {2014-01-01},

journal = {Arthropod Structure and Development},

volume = {43},

number = {5},

pages = {477-492},

publisher = {Elsevier Ltd},

abstract = {The midgut epithelia of the millipedes Polyxenus lagurus, Archispirostreptus gigas and Julus scandinavius were analyzed under light and transmission electron microscopies. In order to detect the proliferation of regenerative cells, labeling with BrdU and antibodies against phosphohistone H3 were employed. A tube-shaped midgut of three millipedes examined spreads along the entire length of the middle region of the body. The epithelium is composed of digestive, secretory and regenerative cells. The digestive cells are responsible for the accumulation of metals and the reserve material as well as the synthesis of substances, which are then secreted into the midgut lumen. The secretions are of three types - merocrine, apocrine and microapocrine. The oval or pear-like shaped secretory cells do not come into contact with the midgut lumen and represent the closed type of secretory cells. They possess many electron-dense granules (. J.scandinavius) or electron-dense granules and electron-lucent vesicles (. A.gigas; P.lagurus), which are accompanied by cisterns of the rough endoplasmic reticulum. The regenerative cells are distributed individually among the basal regions of the digestive cells. The proliferation and differentiation of regenerative cells into the digestive cells occurred in J.scandinavius and A.gigas, while these processes were not observed in P.lagurus. As a resultof the mitotic division of regenerative cells, one of the newly formed cells fulfills the role of a regenerative cell, while the second one differentiates into a digestive cell. We concluded that regenerative cells play the role of unipotent midgut stem cells. © 2014 Elsevier Ltd.},

note = {25},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-84892978126,

title = {The fine structure of the midgut epithelium in a centipede, Scolopendra cingulata (Chilopoda, Scolopendridae), with the special emphasis on epithelial regeneration},

author = { Ł. Chajec and L. Sonakowska and M.M. Rost-Roszkowska},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84892978126&doi=10.1016%2fj.asd.2013.06.002&partnerID=40&md5=8c7ef73411321f19b362f93aae94cf13},

doi = {10.1016/j.asd.2013.06.002},

issn = {14678039},

year  = {2014},

date = {2014-01-01},

journal = {Arthropod Structure and Development},

volume = {43},

number = {1},

pages = {27-42},

abstract = {Scolopendra cingulata has a tube-shaped digestive system that is divided into three distinct regions: fore-, mid- and hindgut. The midgut is lined with a pseudostratified columnar epithelium which is composed of digestive, secretory and regenerative cells. Hemocytes also appear between the digestive cells of the midgut epithelium. The ultrastructure of three types of epithelial cells and hemocytes of the midgut has been described with the special emphasis on the role of regenerative cells in the protection of midgut epithelium. The process of midgut epithelium regeneration proceeds due to the ability of regenerative cells to proliferate and differentiate according to a circadian rhythm. The regenerative cells serve as unipotent stem cells that divide in an asymmetric manner.Additionally, two types of hemocytes have been distinguished among midgut epithelial cells. They enter the midgut epithelium from the body cavity. Because of the fact that numerous microorganisms occur in the cytoplasm of midgut epithelial cells, we discuss the role of hemocytes in elimination of pathogens from the midgut epithelium. The studies were conducted with the use of transmission electron microscope and immunofluorescent methods. © 2013 Elsevier Ltd.},

note = {17},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-84890961691,

title = {Skin care during the menopause period: Noninvasive procedures of beauty studies},

author = { J. Herman and M.M. Rost-Roszkowska and U. Skotnicka-Graca},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84890961691&doi=10.5114%2fpdia.2013.39430&partnerID=40&md5=64ba837e4d0f621ae2bd11fd620936fe},

doi = {10.5114/pdia.2013.39430},

issn = {1642395X},

year  = {2013},

date = {2013-01-01},

journal = {Postepy Dermatologii i Alergologii},

volume = {30},

number = {6},

pages = {388-395},

abstract = {Ageing is a resultant of two processes, including genetically encoded changes in an organism and modifications caused by a negative external environment impact. In the histological aspect, the skin ageing, due to endogenous factors and hormonal changes shows: excessive dryness, Malpighian layer thinning, microcirculation disorders, collagenic or elastin fiber degradation and simultaneous glycation, decreased speed of sebum and perspirationsecretion. It is said that skin is a functional picture of the organism and endocrinological system. Any hormoneconcentration ups and downs may improve its appearance or significantly worsen its condition as well as it maylead to occurrence of dermatological changes. In adult women, the ageing process changes its significance step bystep. Despite the passage of time, women want to feel good inside their skins. The adult skin is more requiring andit needs special care, often using a cosmetic apparatus. For better effect and permanent revitalization of the ageingskin, it is recommended to apply properly selected home-use cosmetic preparations. A holistic approach makes itpossible to reach the skin density and thickness increase, wrinkles shallowing, humidity and resilience improvementand also recovery of the proper face oval. Key words: menopause, skin ageing, hormones, noninvasive cosmetic procedures, mature skin care at home.},

note = {4},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-84880829513,

title = {The fine structure of the midgut epithelium in Xerobiotus pseudohufelandi (Iharos, 1966) (Tardigrada, Eutardigrada, Macrobiotidae)},

author = { M.M. Rost-Roszkowska and I. Poprawa and M. Hyra and M. Marek-Swedzioł and Ł. Kaczmarek},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84880829513&doi=10.4081%2fjlimnol.2013.s1.e7&partnerID=40&md5=d754c69e20672ade3db615f820943563},

doi = {10.4081/jlimnol.2013.s1.e7},

issn = {11295767},

year  = {2013},

date = {2013-01-01},

journal = {Journal of Limnology},

volume = {72},

number = {SUPPL 1},

pages = {54-61},

abstract = {The aims of our studies were to describe the ultrastructure of the midgut epithelial cells of the eutardigrade Xerobiotus pseudohufelandi and to determine if there are any differences in the ultrastructure of midgut epithelial cells between males and females. The analysis was performed with the use of the light and transmission electron microscopes. In X. pseudohufelandi the midgut epithelium is composed of digestive cells, but in the anterior portion of the midgut a group of cells with different ultrastructure has been observed. Histochemical staining showed the accumulation of reserve material in the cytoplasm of digestive cells. We suggest that some of them fulfil the role of regenerative cells (crescent-like cells; midgut stem cells), whereas others are differentiating cells which form new digestive cells. No differences in the ultrastructure of the midgut epithelium between males and females were distinguished except in the amount of multivesicular bodies.},

note = {10},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-84879291028,

title = {Autophagy as the cell survival in response to a microsporidian infection of the midgut epithelium of Isohypsibius granulifer granulifer (Eutardigrada: Hypsibiidae)},

author = { M.M. Rost-Roszkowska and I. Poprawa and Ł. Kaczmarek},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84879291028&doi=10.1111%2fj.1463-6395.2011.00552.x&partnerID=40&md5=8737a2f9f3af90860759af65eeb8943b},

doi = {10.1111/j.1463-6395.2011.00552.x},

issn = {00017272},

year  = {2013},

date = {2013-01-01},

journal = {Acta Zoologica},

volume = {94},

number = {3},

pages = {273-279},

abstract = {The midgut epithelial cells of many invertebrates may possess microorganisms which act as symbionts or pathogens (bacteria; microsporidia; viruses). During our previous studies on Isohypsibius granulifer granulifer Thulin, 1928 (Tardigrada; Eutardigrada), which examined alterations of the midgut epithelium during oogenesis, we found that some of the specimens were infected with microsporidia. All stages of pathogens occurred in the cytoplasm of the digestive cells in the midgut epithelium of I. g. granulifer that were infected with microsporidia: meronts, sporonts, sporoblasts, and spores. The cytoplasm of the digestive cells was rich in mitochondria, cisterns of rough endoplasmic reticulum (RER), and Golgi complexes. Autophagy in the digestive cells of the dorsal midgut was much more intensive in comparison with noninfected specimens. Membranes of phagophores surrounded the pathogens forming autophagosomes. These latter structures fused with lysosomes forming autolysosomes and residual bodies appeared. Neither glycogen granules nor droplets of varying electron density, which accumulated in digestive cells during vitellogenesis and choriogenesis, appeared in individuals with microsporidia. While the midgut epithelium in noninfected specimens takes part in vitellogenesis and choriogenesis, in infected specimens, midgut cells are involved in the process of autophagy as a survival strategy. © 2011 The Authors. Acta Zoologica © 2011 The Royal Swedish Academy of Sciences.},

note = {21},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-84862295360,

title = {Guidelines for the use and interpretation of assays for monitoring autophagy},

author = { M.M. Rost-Roszkowska and D.J. Klionsky and F.C. Abdalla and H. Abeliovich and R.T. Abraham and A. Acevedo-Arozena and K. Adeli and L. Agholme and M. Agnello and P. Agostinis and J.A. Aguirre-Ghiso and H.J. Ahn and O. Ait-Mohamed and S. Ait-Si-Ali and T. Akematsu and S. Akira and H.M. Al-Younes and M.A. Al-Zeer and M.L. Albert and R.L. Albin and J. Alegre-Abarrategui and M.F. Aleo and M. Alirezaei and A. Almasan and M. Almonte-Becerril and A. Amano and R. Amaravadi and S. Amarnath and A.O. Amer and N. Andrieu-Abadie and V. Anantharam and D.K. Ann and S. Anoopkumar-Dukie and H. Aoki and N. Apostolova and G. Arancia and J.P. Aris and K. Asanuma and N.Y.O. Asare and H. Ashida and V. Askanas and D.S. Askew and P. Auberger and M. Baba and S.K. Backues and E.H. Baehrecke and B.A. Bahr and X.Y. Bai and Y. Bailly and R. Baiocchi and G. Baldini and Authors. Other},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84862295360&doi=10.4161%2fauto.19496&partnerID=40&md5=4a625309025c5dc3fadd165b1601ea87},

doi = {10.4161/auto.19496},

issn = {15548627},

year  = {2012},

date = {2012-01-01},

journal = {Autophagy},

volume = {8},

number = {4},

pages = {445-544},

abstract = {In 2008 we published the first set of guidelines for standardizing research in autophagy. Since then, research on this topic has continued to accelerate, and many new scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Accordingly, it is important to update these guidelines for monitoring autophagy in different organisms. Various reviews have described the range of assays that have been used for this purpose. Nevertheless, there continues to be confusion regarding acceptable methods to measure autophagy, especially in multicellular eukaryotes. A key point that needs to be emphasized is that there is a difference between measurements that monitor the numbers or volume of autophagic elements (e.g., autophagosomes or autolysosomes) at any stage of the autophagic process vs. those that measure flux through the autophagy pathway (i.e., the complete process); thus, a block in macroautophagy that results in autophagosome accumulation needs to be differentiated from stimuli that result in increased autophagic activity, defined as increased autophagy induction coupled with increased delivery to, and degradation within, lysosomes (in most higher eukaryotes and some protists such as Dictyostelium) or the vacuole (in plants and fungi). In other words, it is especially important that investigators new to the field understand that the appearance of more autophagosomes does not necessarily equate with more autophagy. In fact, in many cases, autophagosomes accumulate because of a block in trafficking to lysosomes without a concomitant change in autophagosome biogenesis, whereas an increase in autolysosomes may reflect a reduction in degradative activity. Here, we present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes. These guidelines are not meant to be a formulaic set of rules, because the appropriate assays depend in part on the question being asked and the system being used. In addition, we emphasize that no individual assay is guaranteed to be the most appropriate one in every situation, and we strongly recommend the use of multiple assays to monitor autophagy. In these guidelines, we consider these various methods of assessing autophagy and what information can, or cannot, be obtained from them. Finally, by discussing the merits and limits of particular autophagy assays, we hope to encourage technical innovation in the field. © 2012 Landes Bioscience. 

Authors: Klionsky, D.J.; Abdalla, F.C.; Abeliovich, H.; Abraham, R.T.; Acevedo-Arozena, A.; Adeli, K.; Agholme, L.; Agnello, M.; Agostinis, P.; Aguirre-Ghiso, J.A.; Ahn, H.J.; Ait-Mohamed, O.; Ait-Si-Ali, S.; Akematsu, T.; Akira, S.; Al-Younes, H.M.; Al-Zeer, M.A.; Albert, M.L.; Albin, R.L.; Alegre-Abarrategui, J.; Aleo, M.F.; Alirezaei, M.; Almasan, A.; Almonte-Becerril, M.; Amano, A.; Amaravadi, R.; Amarnath, S.; Amer, A.O.; Andrieu-Abadie, N.; Anantharam, V.; Ann, D.K.; Anoopkumar-Dukie, S.; Aoki, H.; Apostolova, N.; Arancia, G.; Aris, J.P.; Asanuma, K.; Asare, N.Y.O.; Ashida, H.; Askanas, V.; Askew, D.S.; Auberger, P.; Baba, M.; Backues, S.K.; Baehrecke, E.H.; Bahr, B.A.; Bai, X.Y.; Bailly, Y.; Baiocchi, R.; Baldini, G.; Balduini, W.; Ballabio, A.; Bamber, B.A.; Bampton, E.T.W.; Bánhegyi, G.; Bartholomew, C.R.; Bassham, D.C.; Bast Jr. R.C.; Batoko, H.; Bay, B.H.; Beau, I.; Béchet, D.M.; Begley, T.J.; Behl, C.; Behrends, C.; Bekri, S.; Bellaire, B.; Bendall, L.J.; Benetti, L.; Berliocchi, L.; Bernardi, H.; Bernassola, F.; Besteiro, S.; Bhatia-Kissova, I.; Bi, X.; Biard-Piechaczyk, M.; Blum, J.S.; Boise, L.H.; Bonaldo, P.; Boone, D.L.; Bornhauser, B.C.; Bortoluci, K.R.; Bossis, I.; Bost, F.; Bourquin, J.P.; Boya, P.; Boyer-Guittaut, M.; Bozhkov, P.V.; Brady, N.R.; Brancolini, C.; Brech, A.; Brenman, J.E.; Brennand, A.; Bresnick, E.H.; Brest, P.; Bridges, D.; Bristol, M.L.; Brookes, P.S.; Brown, E.J.; Brumell, J.H.; Brunetti-Pierri, N.; Brunk, U.T.; Bulman, D.E.; Bultman, S.J.; Bultynck, G.; Burbulla, L.F.; Bursch, W.; Butchar, J.P.; Buzgariu, W.; Bydlowski, S.P.; Cadwell, K.; Cahová, M.; Cai, D.; Cai, J.; Cai, Q.; Calabretta, B.; Calvo-Garrido, J.; Camougrand, N.; Campanella, M.; Campos-Salinas, J.; Candi, E.; Cao, L.; Caplan, A.B.; Carding, S.R.; Cardoso, S.M.; Carew, J.S.; Carlin, C.R.; Carmignac, V.; Carneiro, L.A.M.; Carra, S.; Caruso, R.A.; Casari, G.; Casas, C.; Castino, R.; Cebollero, E.; Cecconi, F.; Celli, J.; Chaachouay, H.; Chae, H.J.; Chai, C.Y.; Chan, D.C.; Chan, E.Y.W.; Chang, R.C.C.; Che, C.M.; Chen, C.C.; Chen, G.C.; Chen, G.Q.; Chen, M.; Chen, Q.; Chen, S.S.L.; Chen, W.; Chen, X.; Chen, X.; Chen, X.; Chen, Y.G.; Chen, Y.; Chen, Y.; Chen, Y.J.; Chen, Z.; Cheng, A.; Cheng, C.H.K.; Cheng, Y.; Cheong, H.; Cheong, J.H.; Cherry, S.; Chess-Williams, R.; Cheung, Z.H.; Chevet, E.; Chiang, H.L.; Chiarelli, R.; Chiba, T.; Chin, L.S.; Chiou, S.H.; Chisari, F.V.; Cho, C.H.; Cho, D.H.; Choi, A.M.K.; Choi, D.; Choi, K.S.; Choi, M.E.; Chouaib, S.; Choubey, D.; Choubey, V.; Chu, C.T.; Chuang, T.H.; Chueh, S.H.; Chun, T.; Chwae, Y.J.; Chye, M.L.; Ciarcia, R.; Ciriolo, M.R.; Clague, M.J.; Clark, R.S.B.; Clarke, P.G.H.; Clarke, R.; Codogno, P.; Coller, H.A.; Colombo, M.I.; Comincini, S.; Condello, M.; Condorelli, F.; Cookson, M.R.; Coombs, G.H.; Coppens, I.; Corbalan, R.; Cossart, P.; Costelli, P.; Costes, S.; Coto-Montes, A.; Couve, E.; Coxon, F.P.; Cregg, J.M.; Crespo, J.L.; Cronjé, M.J.; Cuervo, A.M.; Cullen, J.J.; Czaja, M.J.; D'amelio, M.; Darfeuille-Michaud, A.; Davids, L.M.; Davies, F.E.; De Felici, M.; De Groot, J.F.; De Haan, C.A.M.; De Martino, L.; De Milito, A.; De Tata, V.; Debnath, J.; Degterev, A.; Dehay, B.; Delbridge, L.M.D.; Demarchi, F.; Deng, Y.Z.; Dengjel, J.; Dent, P.; Denton, D.; Deretic, V.; Desai, S.D.; Devenish, R.J.; Di Gioacchino, M.; Di Paolo, G.; Di Pietro, C.; Díaz-Araya, G.; Díaz-Laviada, I.; Diaz-Meco, M.T.; Diaz-Nido, J.; Dikic, I.; Dinesh-Kumar, S.P.; Ding, W.X.; Distelhorst, C.W.; Diwan, A.; Djavaheri-Mergny, M.; Dokudovskaya, S.; Dong, Z.; Dorsey, F.C.; Dosenko, V.; Dowling, J.J.; Doxsey, S.; Dreux, M.; Drew, M.E.; Duan, Q.; Duchosal, M.A.; Duff, K.; Dugail, I.; Durbeej, M.; Duszenko, M.; Edelstein, C.L.; Edinger, A.L.; Egea, G.; Eichinger, L.; Eissa, N.T.; Ekmekcioglu, S.; El-Deiry, W.S.; Elazar, Z.; Elgendy, M.; Ellerby, L.M.; Er Eng, K.; Engelbrecht, A.M.; Engelender, S.; Erenpreisa, J.; Escalante, R.; Esclatine, A.; Eskelinen, E.L.; Espert, L.; Espina, V.; Fan, H.; Fan, J.; Fan, Q.W.; Fan, Z.; Fang, S.; Fang, Y.; Fanto, M.; Fanzani, A.; Farkas, T.; Farré, J.C.; Faure, M.; Fechheimer, M.; Feng, C.G.; Feng, J.; Feng, Q.; Feng, Y.; Fésüs, L.; Feuer, R.; Figueiredo-Pereira, M.E.; Fimia, G.M.; Fingar, D.C.; Finkbeiner, S.; Finkel, T.; Finley, K.D.; Fiorito, F.; Fisher, E.A.; Fisher, P.B.; Flajolet, M.; Florez-McClure, M.L.; Florio, S.; Fon, E.A.; Fornai, F.; Fortunato, F.; Fotedar, R.; Fowler, D.H.; Fox, H.S.; Franco, R.; Frankel, L.B.; Fransen, M.; Fuentes, J.M.; Fueyo, J.; Fujii, J.; Fujisaki, K.; Fujita, E.; Fukuda, M.; Furukawa, R.H.; Gaestel, M.; Gailly, P.; Gajewska, M.; Galliot, B.; Galy, V.; Ganesh, S.; Ganetzky, B.; Ganley, I.G.; Gao, F.B.; Gao, G.F.; Gao, J.; Garcia, L.; Garcia-Manero, G.; Garcia-Marcos, M.; Garmyn, M.; Gartel, A.L.; Gatti, E.; Gautel, M.; Gawriluk, T.R.; Gegg, M.E.; Geng, J.; Germain, M.; Gestwicki, J.E.; Gewirtz, D.A.; Ghavami, S.; Ghosh, P.; Giammarioli, A.M.; Giatromanolaki, A.N.; Gibson, S.B.; Gilkerson, R.W.; Ginger, M.L.; Ginsberg, H.N.; Golab, J.; Goligorsky, M.S.; Golstein, P.; Gomez-Manzano, C.; Goncu, E.; Gongora, C.; Gonzalez, C.D.; Gonzalez, R.; González-Estévez, C.; González-Polo, R.A.; Gonzalez-Rey, E.; Gorbunov, N.V.; Gorski, S.M.; Goruppi, S.; Gottlieb, R.A.; Gozuacik, D.; Granato, G.E.; Grant, G.D.; Green, K.N.; Gregorc, A.; Gros, F.; Grose, C.; Grunt, T.W.; Gual, P.; Guan, J.L.; Guan, K.L.; Guichard, S.M.; Gukovskaya, A.S.; Gukovsky, I.; Gunst, J.; Gustafsson, Å.B.; Halayko, A.J.; Hale, A.N.; Halonen, S.K.; Hamasaki, M.; Han, F.; Han, T.; Hancock, M.K.; Hansen, M.; Harada, H.; Harada, M.; Hardt, S.E.; Harper, J.W.; Harris, A.L.; Harris, J.; Harris, S.D.; Hashimoto, M.; Haspel, J.A.; Hayashi, S.I.; Hazelhurst, L.A.; He, C.; He, Y.W.; Hébert, M.J.; Heidenreich, K.A.; Helfrich, M.H.; Helgason, G.V.; Henske, E.P.; Herman, B.; Herman, P.K.; Hetz, C.; Hilfiker, S.; Hill, J.A.; Hocking, L.J.; Hofman, P.; Hofmann, T.G.; Höhfeld, J.; Holyoake, T.L.; Hong, M.H.; Hood, D.A.; Hotamisligil, G.S.; Houwerzijl, E.J.; Høyer-Hansen, M.; Hu, B.; Hu, C.A.A.; Hu, H.M.; Hua, Y.; Huang, C.; Huang, J.; Huang, S.; Huang, W.P.; Huber, T.B.; Huh, W.K.; Hung, T.H.; Hupp, T.R.; Hur, G.M.; Hurley, J.B.; Hussain, S.N.A.; Hussey, P.J.; Hwang, J.J.; Hwang, S.; Ichihara, A.; Ilkhanizadeh, S.; Inoki, K.; Into, T.; Iovane, V.; Iovanna, J.L.; Ip, N.Y.; Isaka, Y.; Ishida, H.; Isidoro, C.; Isobe, K.I.; Iwasaki, A.; Izquierdo, M.; Izumi, Y.; Jaakkola, P.M.; Jäättelä, M.; Jackson, G.R.; Jackson, W.T.; Janji, B.; Jendrach, M.; Jeon, J.H.; Jeung, E.B.; Jiang, H.; Jiang, H.; Jiang, J.X.; Jiang, M.; Jiang, Q.; Jiang, X.; Jiménez, A.; Jin, M.; Jin, S.; Joe, C.O.; Johansen, T.; Johnson, D.E.; Johnson, G.V.W.; Jones, N.L.; Joseph, B.; Joseph, S.K.; Joubert, A.M.; Juhász, G.; Juillerat-Jeanneret, L.; Jung, C.H.; Jung, Y.K.; Kaarniranta, K.; Kaasik, A.; Kabuta, T.; Kadowaki, M.; Kågedal, K.; Kamada, Y.; Kaminskyy, V.O.; Kampinga, H.H.; Kanamori, H.; Kang, C.; Kang, K.B.; Il Kang, K.; Kang, R.; Kang, Y.A.; Kanki, T.; Kanneganti, T.D.; Kanno, H.; Kanthasamy, A.G.; Kanthasamy, A.; Karantza, V.; Kaushal, G.P.; Kaushik, S.; Kawazoe, Y.; Ke, P.Y.; Kehrl, J.H.; Kelekar, A.; Kerkhoff, C.; Kessel, D.H.; Khalil, H.; Kiel, J.A.K.W.; Kiger, A.A.; Kihara, A.; Kim, D.R.; Kim, D.H.; Kim, D.H.; Kim, E.K.; Kim, H.R.; Kim, J.S.; Kim, J.H.; Kim, J.C.; Kim, J.K.; Kim, P.K.; Kim, S.W.; Kim, Y.S.; Kim, Y.; Kimchi, A.; Kimmelman, A.C.; King, J.S.; Kinsella, T.J.; Kirkin, V.; Kirshenbaum, L.A.; Kitamoto, K.; Kitazato, K.; Klein, L.; Klimecki, W.T.; Klucken, J.; Knecht, E.; Ko, B.C.B.; Koch, J.C.; Koga, H.; Koh, J.Y.; Koh, Y.H.; Koike, M.; Komatsu, M.; Kominami, E.; Kong, H.J.; Kong, W.J.; Korolchuk, V.I.; Kotake, Y.; Koukourakis, M.I.; Kouri Flores, J.B.; Kovács, A.L.; Kraft, C.; Krainc, D.; Krämer, H.; Kretz-Remy, C.; Krichevsky, A.M.; Kroemer, G.; Krüger, R.; Krut, O.; Ktistakis, N.T.; Kuan, C.Y.; Kucharczyk, R.; Kumar, A.; Kumar, R.; Kumar, S.; Kundu, M.; Kung, H.J.; Kurz, T.; Kwon, H.J.; La Spada, A.R.; Lafont, F.; Lamark, T.; Landry, J.; Lane, J.D.; Lapaquette, P.; Laporte, J.F.; László, L.; Lavandero, S.; Lavoie, J.N.; Layfield, R.; Lazo, P.A.; Le, W.; Le Cam, L.; Ledbetter, D.J.; Lee, A.J.X.; Lee, B.W.; Lee, G.M.; Lee, J.; Lee, J.H.; Lee, M.; Lee, M.S.; Lee, S.H.; Leeuwenburgh, C.; Legembre, P.; Legouis, R.; Lehmann, M.; Lei, H.Y.; Lei, Q.Y.; Leib, D.A.; Leiro, J.; Lemasters, J.J.; Lemoine, A.; Lesniak, M.S.; Lev, D.; Levenson, V.V.; Levine, B.; Levy, E.; Li, F.; Li, J.L.; Li, L.; Li, S.; Li, W.; Li, X.J.; Li, Y.B.; Li, Y.P.; Liang, C.; Liang, Q.; Liao, Y.F.; Liberski, P.P.; Lieberman, A.P.; Lim, H.J.; Lim, K.L.; Lim, K.; Lin, C.F.; Lin, F.C.; Lin, J.; Lin, J.D.; Lin, K.; Lin, W.W.; Lin, W.C.; Lin, Y.L.; Linden, R.; Lingor, P.; Lippincott-Schwartz, J.; Lisanti, M.P.; Liton, P.B.; Liu, B.; Liu, C.F.; Liu, K.; Liu, L.; Liu, Q.A.; Liu, W.; Liu, Y.C.; Liu, Y.; Lockshin, R.A.; Lok, C.N.; Lonial, S.; Loos, B.; Lopez-Berestein, G.; López-Otín, C.; Lossi, L.; Lotze, M.T.; Lõw, P.; Lu, B.; Lu, B.; Lu, B.; Lu, Z.; Luciano, F.; Lukacs, N.W.; Lund, A.H.; Lynch-Day, M.A.; Ma, Y.; Macian, F.; MacKeigan, J.P.; Macleod, K.F.; Madeo, F.; Maiuri, L.; Maiuri, M.C.; Malagoli, D.; Malicdan, M.C.V.; Malorni, W.; Man, N.; Mandelkow, E.M.; Manon, S.; Manov, I.; Mao, K.; Mao, X.; Mao, Z.; Marambaud, P.; Marazziti, D.; Marcel, Y.L.; Marchbank, K.; Marchetti, P.; Marciniak, S.J.; Marcondes, M.; Mardi, M.; Marfe, G.; Mariño, G.; Markaki, M.; Marten, M.R.; Martin, S.J.; Martinand-Mari, C.; Martinet, W.; Martinez-Vicente, M.; Masini, M.; Matarrese, P.; Matsuo, S.; Matteoni, R.; Mayer, A.; Mazure, N.M.; McConkey, D.J.; McConnell, M.J.; McDermott, C.; McDonald, C.; McInerney, G.M.; McKenna, S.L.; McLaughlin, B.; McLean, P.J.; McMaster, C.R.; McQuibban, G.A.; Meijer, A.J.; Meisler, M.H.; Meléndez, A.; Melia, T.J.; Melino, G.; Mena, M.A.; Menendez, J.A.; Menna-Barreto, R.F.S.; Menon, M.B.; Menzies, F.M.; Mercer, C.A.; Merighi, A.; Merry, D.E.; Meschini, S.; Meyer, C.G.; Meyer, T.F.; Miao, C.Y.; Miao, J.Y.; Michels, P.A.M.; Michiels, C.; Mijaljica, D.; Milojkovic, A.; Minucci, S.; Miracco, C.; Miranti, C.K.; Mitroulis, I.; Miyazawa, K.; Mizushima, N.; Mograbi, B.; Mohseni, S.; Molero, X.; Mollereau, B.; Mollinedo, F.; Momoi, T.; Monastyrska, I.; Monick, M.M.; Monteiro, M.J.; Moore, M.N.; Mora-Rodriguez, R.; Moreau, K.; Moreira, P.I.; Moriyasu, Y.; Moscat, J.; Mostowy, S.; Mottram, J.C.; Motyl, T.; Moussa, C.E.H.; Müller, S.; Muller, S.; Münger, K.; Münz, C.; Murphy, L.O.; Murphy, M.E.; Musarò, A.; Mysorekar, I.U.; Nagata, E.; Nagata, K.; Nahimana, A.; Nair, U.; Nakagawa, T.; Nakahira, K.; Nakano, H.; Nakatogawa, H.; Nanjundan, M.; Naqvi, N.I.; Narendra, D.P.; Narita, M.; Navarro, M.; Nawrocki, S.T.; Nazarko, T.Y.; Nemchenko, A.; Netea, M.G.; Neufeld, T.P.; Ney, P.A.; Nezis, I.P.; Nguyen, H.P.; Nie, D.; Nishino, I.; Nislow, C.; Nixon, R.A.; Noda, T.; Noegel, A.A.; Nogalska, A.; Noguchi, S.; Notterpek, L.; Novak, I.; Nozaki, T.; Nukina, N.; Nürnberger, T.; Nyfeler, B.; Obara, K.; Oberley, T.D.; Oddo, S.; Ogawa, M.; Ohashi, T.; Okamoto, K.; Oleinick, N.L.; Oliver, F.J.; Olsen, L.J.; Olsson, S.; Opota, O.; Osborne, T.F.; Ostrander, G.K.; Otsu, K.; Ou, J.H.J.; Ouimet, M.; Overholtzer, M.; Ozpolat, B.; Paganetti, P.; Pagnini, U.; Pallet, N.; Palmer, G.E.; Palumbo, C.; Pan, T.; Panaretakis, T.; Pandey, U.B.; Papackova, Z.; Papassideri, I.; Paris, I.; Park, J.; Park, O.K.; Parys, J.B.; Parzych, K.R.; Patschan, S.; Patterson, C.; Pattingre, S.; Pawelek, J.M.; Peng, J.; Perlmutter, D.H.; Perrotta, I.; Perry, G.; Pervaiz, S.; Peter, M.; Peters, G.J.; Petersen, M.; Petrovski, G.; Phang, J.M.; Piacentini, M.; Pierre, P.; Pierrefite-Carle, V.; Pierron, G.; Pinkas-Kramarski, R.; Piras, A.; Piri, N.; Platanias, L.C.; Pöggeler, S.; Poirot, M.; Poletti, A.; Poüs, C.; Pozuelo-Rubio, M.; Prætorius-Ibba, M.; Prasad, A.; Prescott, M.; Priault, M.; Produit-Zengaffinen, N.; Progulske-Fox, A.; Proikas-Cezanne, T.; Przedborski, S.; Przyklenk, K.; Puertollano, R.; Puyal, J.; Qian, S.B.; Qin, L.; Qin, Z.H.; Quaggin, S.E.; Raben, N.; Rabinowich, H.; Rabkin, S.W.; Rahman, I.; Rami, A.; Ramm, G.; Randall, G.; Randow, F.; Rao, V.A.; Rathmell, J.C.; Ravikumar, B.; Ray, S.K.; Reed, B.H.; Reed, J.C.; Reggiori, F.; Régnier-Vigouroux, A.; Reichert, A.S.; Reiners Jr. J.J.; Reiter, R.J.; Ren, J.; Revuelta, J.L.; Rhodes, C.J.; Ritis, K.; Rizzo, E.; Robbins, J.; Roberge, M.; Roca, H.; Roccheri, M.C.; Rocchi, S.; Rodemann, H.P.; De Córdoba, S.R.; Rohrer, B.; Roninson, I.B.; Rosen, K.V.; Rost-Roszkowska, M.M.; Rouis, M.; Rouschop, K.M.A.; Rovetta, F.; Rubin, B.P.; Rubinsztein, D.C.; Ruckdeschel, K.; Rucker, E.B.; Rudich, A.; Rudolf, E.; Ruiz-Opazo, N.; Russo, R.; Rusten, T.E.; Ryan, K.M.; Ryter, S.W.; Sabatini, D.M.; Sadoshima, J.; Saha, T.; Saitoh, T.; Sakagami, H.; Sakai, Y.; Salekdeh, G.H.; Salomoni, P.; Salvaterra, P.M.; Salvesen, G.; Salvioli, R.; Sanchez, A.M.J.; Sánchez-Alcázar, J.A.; Sánchez-Prieto, R.; Sandri, M.; Sankar, U.; Sansanwal, P.; Santambrogio, L.; Saran, S.; Sarkar, S.; Sarwal, M.M.; Sasakawa, C.; Sasnauskiene, A.; Sass, M.; Sato, K.; Sato, M.; Schapira, A.H.V.; Scharl, M.; Schätzl, H.M.; Scheper, W.; Schiaffino, S.; Schneider, C.; Schneider, M.E.; Schneider-Stock, R.; Schoenlein, P.V.; Schorderet, D.F.; Schüller, C.; Schwartz, G.K.; Scorrano, L.; Sealy, L.; Seglen, P.O.; Segura-Aguilar, J.; Seiliez, I.; Seleverstov, O.; Sell, C.; Seo, J.B.; Separovic, D.; Setaluri, V.; Setoguchi, T.; Settembre, C.; Shacka, J.J.; Shanmugam, M.; Shapiro, I.M.; Shaulian, E.; Shaw, R.J.; Shelhamer, J.H.; Shen, H.M.; Shen, W.C.; Sheng, Z.H.; Shi, Y.; Shibuya, K.; Shidoji, Y.; Shieh, J.J.; Shih, C.M.; Shimada, Y.; Shimizu, S.; Shintani, T.; Shirihai, O.S.; Shore, G.C.; Sibirny, A.A.; Sidhu, S.B.; Sikorska, B.; Silva-Zacarin, E.C.M.; Simmons, A.; Simon, A.K.; Simon, H.U.; Simone, C.; Simonsen, A.; Sinclair, D.A.; Singh, R.; Sinha, D.; Sinicrope, F.A.; Sirko, A.; Siu, P.M.; Sivridis, E.; Skop, V.; Skulachev, V.P.; Slack, R.S.; Smaili, S.S.; Smith, D.R.; Soengas, M.S.; Soldati, T.; Song, X.; Sood, A.K.; Soong, T.W.; Sotgia, F.; Spector, S.A.; Spies, C.D.; Springer, W.; Srinivasula, S.M.; Stefanis, L.; Steffan, J.S.; Stendel, R.; Stenmark, H.; Stephanou, A.; Stern, S.T.; Sternberg, C.; Stork, B.; Strålfors, P.; Subauste, C.S.; Sui, X.; Sulzer, D.; Sun, J.; Sun, S.Y.; Sun, Z.J.; Sung, J.J.Y.; Suzuki, K.; Suzuki, T.; Swanson, M.S.; Swanton, C.; Sweeney, S.T.; Sy, L.K.; Szabadkai, G.; Tabas, I.; Taegtmeyer, H.; Tafani, M.; Takács-Vellai, K.; Takano, Y.; Takegawa, K.; Takemura, G.; Takeshita, F.; Talbot, N.J.; Tan, K.S.W.; Tanaka, K.; Tanaka, K.; Tang, D.; Tang, D.; Tanida, I.; Tannous, B.A.; Tavernarakis, N.; Taylor, G.S.; Taylor, G.A.; Taylor, J.P.; Terada, A.S.; Terman, A.; Tettamanti, G.; Thevissen, K.; Thompson, C.B.; Thorburn, A.; Thumm, M.; Tian, F.; Tian, Y.; Tocchini-Valentini, G.; Tolkovsky, A.M.; Tomino, Y.; Tönges, L.; Tooze, S.A.; Tournier, C.; Tower, J.; Towns, R.; Trajkovic, V.; Travassos, L.H.; Tsai, T.F.; Tschan, M.P.; Tsubata, T.; Tsung, A.; Turk, B.; Turner, L.S.; Tyagi, S.C.; Uchiyama, Y.; Ueno, T.; Umekawa, M.; Umemiya-Shirafuji, R.; Unni, V.K.; Vaccaro, M.I.; Valente, E.M.; Van den Berghe, G.; van der Klei, I.J.; van Doorn, W.G.; Van Dyk, L.F.; van Egmond, M.; Van Grunsven, L.A.; Vandenabeele, P.; Vandenberghe, W.P.; Vanhorebeek, I.; Vaquero, E.C.; Velasco, G.; Vellai, T.; Vicencio, J.M.; Vierstra, R.D.; Vila, M.; Vindis, C.; Viola, G.; Viscomi, M.T.; Voitsekhovskaja, O.V.; von Haefen, C.; Votruba, M.; Wada, K.; Wade-Martins, R.; Walker, C.L.; Walsh, C.M.; Walter, J.; Wan, X.B.; Wang, A.; Wang, C.; Wang, D.; Wang, F.; Wang, F.; Wang, G.; Wang, H.; Wang, H.G.; Wang, H.D.; Wang, J.; Wang, K.; Wang, M.; Wang, R.C.; Wang, X.; Wang, X.; Wang, Y.J.; Wang, Y.; Wang, Z.; Wang, Z.C.; Wang, Z.N.; Wansink, D.G.; Ward, D.M.V.; Watada, H.; Waters, S.L.; Webster, P.; Wei, L.; Weihl, C.C.; Weiss, W.A.; Welford, S.M.; Wen, L.P.; Whitehouse, C.A.; Whitton, J.L.; Whitworth, A.J.; Wileman, T.; Wiley, J.W.; Wilkinson, S.; Willbold, D.; Williams, R.L.; Williamson, P.R.; Wouters, B.G.; Wu, C.; Wu, D.C.; Wu, W.K.K.; Wyttenbach, A.; Xavier, R.J.; Xi, Z.; Xia, P.; Xiao, G.; Xie, Z.; Xie, Z.; Xu, D.Z.; Xu, J.; Xu, L.; Xu, X.; Yamamoto, A.; Yamamoto, A.; Yamashina, S.; Yamashita, M.; Yan, X.; Yanagida, M.; Yang, D.S.; Yang, E.; Yang, J.M.; Yang, S.Y.; Yang, W.; Yang, W.Y.; Yang, Z.; Yao, M.C.; Yao, T.P.; Yeganeh, B.; Yen, W.L.; Yin, J.J.; Yin, X.M.; Yoo, O.J.; Yoon, G.; Yoon, S.Y.; Yorimitsu, T.; Yoshikawa, Y.; Yoshimori, T.; Yoshimoto, K.; You, H.J.; Youle, R.J.; Younes, A.; Yu, L.; Yu, L.; Yu, S.W.; Yu, W.H.; Yuan, Z.M.; Yue, Z.; Yun, C.H.; Yuzaki, M.; Zabirnyk, O.; Silva-Zacarin, E.C.M.; David Zacks, E.; Zacksenhaus, L.; Zaffaroni, N.; Zakeri, Z.; Zeh III, H.J.; Zeitlin, S.O.; Zhang, H.; Zhang, H.L.; Zhang, J.; Zhang, J.P.; Zhang, L.; Zhang, L.; Zhang, M.Y.; Zhang, X.D.; Zhao, M.; Zhao, Y.F.; Zhao, Y.; Zhao, Z.J.; Zheng, X.; Zhivotovsky, B.; Zhong, Q.; Zhou, C.Z.; Zhu, C.; Zhu, W.G.; Zhu, X.F.; Zhu, X.; Zhu, Y.; Zoladek, T.; Zong, W.X.; Zorzano, A.; Zschocke, J.; Zuckerbraun, B.},

note = {2686},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-84862337647,

title = {Morphology and ultrastructure of the midgut in Piscicola geometra (Annelida, Hirudinea)},

author = { M.M. Rost-Roszkowska and P. Świątek and M. Kszuk and K. Główczyk and A. Bielecki},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84862337647&doi=10.1007%2fs00709-011-0337-7&partnerID=40&md5=bed009bb9d52aeeca17f0c365d4556ee},

doi = {10.1007/s00709-011-0337-7},

issn = {0033183X},

year  = {2012},

date = {2012-01-01},

journal = {Protoplasma},

volume = {249},

number = {4},

pages = {1037-1047},

publisher = {Springer-Verlag Wien},

abstract = {This paper presents information on the organization of the midgut and its epithelium ultrastructure in juvenile and adult specimens of Piscicola geometra (Annelida; Hirudinea), a species which is a widespread ectoparasite found on the body and gills and in the mouth of many types of fish. The analysis of juvenile nonfeeding specimens helped in the explanation of all alterations in the midgut epithelium which are connected with digestion. The endodermal portion (midgut) of the digestive system is composed of four regions: the esophagus, the crop, the posterior crop caecum, and the intestine. Their epithelia are formed by flat, cuboidal, or columnar digestive cells; however, single small cells which do not contact the midgut lumen were also observed. The ultrastructure of all of the regions of the midgut are described and discussed with a special emphasis on their functions in the digestion of blood. In P. geometra, the part of the midgut that is devoid of microvilli is responsible for the accumulation of blood, while the epithelium of the remaining part of the midgut, which has a distinct regionalization in the distribution of organelles, plays a role in its absorption and secretion. Glycogen granules in the intestinal epithelium indicate its role in the accumulation of sugar. The comparison of the ultrastructure of midgut epithelium in juvenile and adult specimens suggests that electron-dense granules observed in the apical cytoplasm of digestive cells take part in enzyme accumulation. Numerous microorganisms were observed in the mycetome, which is composed of two large oval diverticles that connect with the esophagus via thin ducts. Similar microorganisms also occurred in the cytoplasm of the epithelium in the esophagus, the crop, the intestine, and in their lumen. Microorganisms were observed both in fed adult and unfed juvenile specimens of P. geometra, which strongly suggests that vertical transmission occurs from parent to offspring. © 2011 The Author(s).},

note = {8},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-84862319702,

title = {Ultrastructure and regeneration of midgut epithelial cells in Lithobius forficatus (Chilopoda, Lithobiidae)},

author = { Ł. Chajec and M.M. Rost-Roszkowska and J. Vilimová and A. Sosinka},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84862319702&doi=10.1111%2fj.1744-7410.2012.00264.x&partnerID=40&md5=5abb432b567a5d771b5bf86d35719751},

doi = {10.1111/j.1744-7410.2012.00264.x},

issn = {10778306},

year  = {2012},

date = {2012-01-01},

journal = {Invertebrate Biology},

volume = {131},

number = {2},

pages = {119-132},

abstract = {Lithobius forficatus (Myriapoda; Chilopoda; Lithobiidae) is a widespread species of centipede that is common across Europe. Its midgut epithelial cells are an important line of defense against toxic substances that originate in food, such as pathogens and metals. Despite this important role, the biology of the midgut epithelium is not well known. Here we describe the ultrastructure of the midgut epithelium, as well as the replacement of degenerated midgut epithelial cells. The midgut epithelium of L. forficatus is composed of digestive, secretory, and regenerative cells. The cytoplasm of digestive cells shows regionalization in organelle distribution, which is consistent with the role of these cells in secretion of enzymes, absorption of nutrients, and accumulation of lipids and glycogen. Secretory cells, which do not reach the luminal surface of the midgut epithelium, possess numerous electron-dense and electron-lucent granules and may have an endocrine function. Hemidesmosomes anchor secretory cells to the basal lamina. Regenerative cells play the role of midgut stem cells, as they are able to proliferate and differentiate. Their proliferation occurs in a continuous manner, and their progeny differentiate only into digestive cells. The regeneration of secretory cells was not observed. Mitotic divisions of regenerative cells were confirmed using immunolabeling against BrdU and phosphohistone H3. Hemocytes associate with the midgut epithelium, accumulating between the visceral muscles and beneath the basal lamina of the midgut epithelium. Hemocytes also occur among the digestive cells of the midgut epithelium in animals infected with Rickettsia-like microorganisms. These hemocytes presumably have an immunoprotective function in the midgut. © 2012 The American Microscopical Society, Inc.},

note = {20},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-84860582843,

title = {The role of autophagy in the midgut epithelium of Eubranchipus grubii (Crustacea, Branchiopoda, Anostraca)},

author = { M.M. Rost-Roszkowska and J. Vilimová and A. Sosinka and J. Skudlik and E. Franzetti},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84860582843&doi=10.1016%2fj.asd.2012.01.001&partnerID=40&md5=a1812dfbcd6ca9a872cda5d84aa9dbc6},

doi = {10.1016/j.asd.2012.01.001},

issn = {14678039},

year  = {2012},

date = {2012-01-01},

journal = {Arthropod Structure and Development},

volume = {41},

number = {3},

pages = {271-279},

abstract = {Eubranchipus grubii (Crustacea; Branchiopoda; Anostraca) is an omnivorous filter feeder whose life span lasts no more than 12 weeks. Adult males and females of E. grubii were used for ultrastructural studies of the midgut epithelium and an analysis of autophagy. The midgut epithelium is formed by columnar digestive cells and no regenerative cells were observed. A distinct regionalization in the distribution of organelles appears - basal, perinuclear and apical regions were distinguished. No differences in the ultrastructure of digestive cells were observed between males and females. Autophagic disintegration of organelles occurs throughout the midgut epithelium. Degenerated organelles accumulate in the neighborhood of Golgi complexes, and these complexes presumably take part in phagophore and autophagosome formation. In some cases, the phagophore also surrounds small autophagosomes, which had appeared earlier. Fusion of autophagosomes and lysosomes was not observed, but lysosomes are enclosed during autophagosome formation. Autophagosomes and autolysosomes are discharged into the midgut lumen due to apocrine secretion. Autophagy plays a role in cell survival by protecting the cell from cell death. © 2012 Elsevier Ltd.},

note = {30},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{nokey,

title = {Guidelines for the use and interpretation of assays for monitoring autophagy},

author = { M.M. Rost-Roszkowska and D.J. Klionsky and F.C. Abdalla and H. Abeliovich and R.T. Abraham and A. Acevedo-Arozena and K. Adeli and L. Agholme and M. Agnello and P. Agostinis and J.A. Aguirre-Ghiso and H.J. Ahn and O. Ait-Mohamed and S. Ait-Si-Ali and T. Akematsu and S. Akira and H.M. Al-Younes and M.A. Al-Zeer and M.L. Albert and R.L. Albin and J. Alegre-Abarrategui and M.F. Aleo and M. Alirezaei and A. Almasan and M. Almonte-Becerril and A. Amano and R. Amaravadi and S. Amarnath and A.O. Amer and N. Andrieu-Abadie and V. Anantharam and D.K. Ann and S. Anoopkumar-Dukie and H. Aoki and N. Apostolova and G. Arancia and J.P. Aris and K. Asanuma and N.Y.O. Asare and H. Ashida and V. Askanas and D.S. Askew and P. Auberger and M. Baba and S.K. Backues and E.H. Baehrecke and B.A. Bahr and X.Y. Bai and Y. Bailly and R. Baiocchi and G. Baldini and Authors. Other},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84862295360&doi=10.4161%2fauto.19496&partnerID=40&md5=4a625309025c5dc3fadd165b1601ea87},

doi = {10.4161/auto.19496},

year  = {2012},

date = {2012-01-01},

journal = {Autophagy},

volume = {8},

number = {4},

pages = {445-544},

note = {2753},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-79953234823,

title = {Ultrastructural changes of the midgut epithelium in Isohypsibius granulifer granulifer Thulin, 1928 (Tardigrada: Eutardigrada) during oogenesis},

author = { M.M. Rost-Roszkowska and I. Poprawa and M. Wójtowicz and Ł. Kaczmarek},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-79953234823&doi=10.1007%2fs00709-010-0186-9&partnerID=40&md5=2c1b8e156b11c6cf009e2cd8b0d326bc},

doi = {10.1007/s00709-010-0186-9},

issn = {0033183X},

year  = {2011},

date = {2011-01-01},

journal = {Protoplasma},

volume = {248},

number = {2},

pages = {405-414},

abstract = {The midgut epithelium of Isohypsibius granulifer granulifer (Eutardigrada) is composed of columnar digestive cells. At its anterior end, a group of cells with cytoplasm which differs from the cytoplasm of digestive cells is present. Probably, those cells respond to crescent-like cells (midgut regenerative cells) described for some tardigrade species. Their mitotic divisions have not been observed. We analyzed the ultrastructure of midgut digestive cells in relation to five different stages of oogenesis (previtellogenesis; beginning of the vitellogenesis; vitellogenesis-early choriogenesis; vitellogenesis-middle choriogenesis; late choriogenesis). In the midgut epithelium cells, the gradual accumulation of glycogen granules, lipid droplets and structures of varying electron density occurs. During vitellogenesis and choriogenesis, in the cytoplasm of midgut cells we observed the increasing number of organelles which are responsible for the intensive synthesis of lipids, proteins and saccharides such as cisterns of endoplasmic reticulum and Golgi complexes. At the end of oogenesis, autophagy also intensifies in midgut epithelial cells, which is probably caused by the great amount of reserve material. Midgut epithelium of analyzed species takes part in the yolk precursor synthesis. © 2010 Springer-Verlag.},

note = {27},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-79251634725,

title = {Origin of the brushborder in the differentiating midgut of Melasoma saliceti (Chrysomelidae, Coleoptera) embryos},

author = { M.M. Rost-Roszkowska and J. Klag},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-79251634725&doi=10.3409%2ffb59-1-2.53-58&partnerID=40&md5=975e94f97ec08c28c0b210ff980f681d},

doi = {10.3409/fb59-1-2.53-58},

issn = {00155500},

year  = {2011},

date = {2011-01-01},

journal = {Folia Biologica},

volume = {59},

number = {1-2},

pages = {53-58},

publisher = {Charles University},

abstract = {The embryonic development of Melasoma saliceti takes eight days at room temperature. At the beginning of the 5th day the endoderm cells have already formed a unilayered epithelium of the midgut primordium. The midgut epithelium is formed by flat cells that are not connected by specialized intercellular junctions. Large vesicles can be seen in dilated intercellular spaces of the epithelium. Cytoplasmic projections, similar to microvilli, appear in the vesicles. During the 5th day of development, the vesicles grow and become enclosed by the intercellular junctions of a zonula adherens type. During the 6th day of development the cell junctions surrounding the vesicles become transformed into a septate type. On the 8th day of development the vesicles come close to the apical sides of the midgut cells and open towards the yolk. At the same time the microvilli spread over the apical surface of the midgut primordium to form the regular brushborder of the larval midgut. In the species studied the vesicles appear to "prefabricate" the apical surfaces of the future midgut epithelium. © Institute of Systematics and Evolution of Animals, PAS, 2011.},

note = {2},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-78650169528,

title = {Fine structure of the midgut epithelium in two Archaeognatha, Lepismachilis notata and Machilis hrabei (Insecta), in relation to its degeneration and regeneration},

author = { M.M. Rost-Roszkowska and P. Jansta and J. Vilimová},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-78650169528&doi=10.1007%2fs00709-010-0148-2&partnerID=40&md5=1d001f4f36e264b7f9a99dc831107b1f},

doi = {10.1007/s00709-010-0148-2},

issn = {0033183X},

year  = {2010},

date = {2010-01-01},

journal = {Protoplasma},

volume = {247},

number = {1},

pages = {91-101},

abstract = {In two archaeognathans, Lepismachilis notata and Machilis hrabei, the midgut epithelium and processes of its regeneration and degeneration have been described at the ultrastructural level. In both analysed species, the midgut epithelium is composed of epithelial and regenerative cells (regenerative nests). The epithelial cells show distinct regionalization in organelles distribution with the basal, perinuclear, and apical regions being distinguished. Degeneration of epithelial cells proceeds in a necrotic way (continuous degeneration) during the entire life of adult specimens, but just before each moult degeneration intensifies. Apoptosis has been observed. Regenerative cells fulfil the role of midgut stem cells. Some of them proliferate, while the others differentiate into epithelial cells. We compared the organisation of the midgut epithelium of M. hrabei and L. notata with zygentoman species, which have just been described. © 2010 Springer-Verlag.},

note = {17},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-77957775200,

title = {Differentiation of regenerative cells in the midgut epithelium of epilachna cf. nylanderi (Mulsant 1850) (insecta, coleoptera, coccinellidae)},

author = { M.M. Rost-Roszkowska and I. Poprawa and J. Klag and P. Migula and J. Mesjasz-Przybyłowicz and W.J. Przybyłowicz},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-77957775200&doi=10.3409%2ffb58_3-4.209-216&partnerID=40&md5=80d12a2aefa0799eb3551551788a56a9},

doi = {10.3409/fb58_3-4.209-216},

issn = {00155497},

year  = {2010},

date = {2010-01-01},

journal = {Folia Biologica},

volume = {58},

number = {3-4},

pages = {209-216},

abstract = {Differentiation of regenerative cells in the midgut epithelium of Epilachna cf. nylanderi (Mulsant 1850) (Insecta; Coleoptera; Coccinellidae), a consumer of the Ni-hyperaccumulator Berkheya coddii (Asteracae) from South Africa, has been monitored and described. Adult specimens in various developmental phaseswere studiedwith the use of lightmicroscopy and transmission electron microscopy. All degenerated epithelial cells are replaced by newly differentiated cells. They originate from regenerative cells which act as stem cells in the midgut epithelium. Just after pupal-adult transformation, the midgut epithelium of E. nylanderi is composed of columnar epithelial cells and isolated regenerative cells distributed among them. The regenerative cells proliferate intensively and form regenerative cell groups. In each regenerative cell group the majority of cells differentiate into new epithelial cells, while some of them still act as stem cells and persist as a reservoir of cells capable for proliferation and differentiation. Because this species is an obligate monophage of plants which accumulate nickel, proliferation and differentiation of midgut stem cells follow degeneration intensively and in a typical manner.},

note = {17},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-77957762715,

title = {Fine structure of the midgut epithelium of nicoletia phytophila gervais, 1844 (Zygentoma: Nicoletiidae: Nicoletiinae) with special emphasis on its degeneration},

author = { M.M. Rost-Roszkowska and J. Vilimová and Ł. Chajec},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-77957762715&doi=10.3409%2ffb58_3-4.217-227&partnerID=40&md5=0120af7b4b6d14185cde22aca75275a9},

doi = {10.3409/fb58_3-4.217-227},

issn = {00155497},

year  = {2010},

date = {2010-01-01},

journal = {Folia Biologica},

volume = {58},

number = {3-4},

pages = {217-227},

abstract = {The midgut epithelium of Nicoletia phytophila is composed of columnar digestive cells and regenerative cells that form regenerative nests. The cytoplasm of midgut epithelial cells shows typical regionalization in organelle distribution. Two types of regenerative cells have been distinguished: cells which are able to divide intensively and cells which differentiate. Spot desmosomes have been observed between neighboring regenerative cells. The occurrence of intercellular junctions is discussed. Themidgut epitheliumdegenerates both in an apoptotic and necrotic way. Necrosis proceeds during each molting period (cyclic manner), while apoptosis occurs between each molting, when the midgut epithelium is responsible for e.g. digestion. These processes of epithelium degeneration are described at the ultrastructural level. Our studies not only add new information about fine structure of the midgut epithelium of N. phytophila, but contribute to resolving the relationships within the Zygentoma. There are no doubts about the very close sister position of Nicoletiidae and Ateluridae. The midgut epithelium characters confirm their close relationship. However we do not recommend classifying the atelurid genera only within Nicoletiidae: Nicoletiinae.},

note = {8},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-77956465521,

title = {Apoptosis and autophagy in the midgut epithelium of Acheta domesticus (Insecta, Orthoptera, Gryllidae)},

author = { M.M. Rost-Roszkowska and I. Poprawa and A. Chachulska-Żymełka},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-77956465521&doi=10.2108%2fzsj.27.740&partnerID=40&md5=fabe9e7f3c40eb1eb7a363ad398cacef},

doi = {10.2108/zsj.27.740},

issn = {02890003},

year  = {2010},

date = {2010-01-01},

journal = {Zoological Science},

volume = {27},

number = {9},

pages = {740-745},

abstract = {The midgut epithelium of Acheta domesticus (Insecta; Orthoptera; Gryllidae), which is composed of columnar digestive cells and regenerative crypts, degenerates in two manners: necrotic and apoptotic. While necrosis was described in our previous paper, programmed cell death was the aim of the present studies. The first morphological signs of programmed cell death in midgut epithelium cells are alterations in the cytoplasm connected with shrinkage of the cells. Gradual modifications in a cell's structure cause it to be discharged into the midgut lumen, where it disintegrates. Autophagy is involved in the disintegration of organelles. The transitions of apoptotic cells are described at the ultrastructural level. Immunostaining methods were used in order to indicate the early stages of apoptosis when DNA fragmentation, which results from apoptotic signaling cascades, occurs. © 2010 Zoological Society of Japan.},

note = {25},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-77956488408,

title = {Fine structure of the midgut epithelium of Atelura formicaria (Hexapoda: Zygentoma: Ateluridae), with special reference to its regeneration and degeneration},

author = { M.M. Rost-Roszkowska and J. Vilimová and Ł. Chajec},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-77956488408&partnerID=40&md5=58f419c2204aadc7e57fbe6ef058f668},

issn = {10215506},

year  = {2010},

date = {2010-01-01},

journal = {Zoological Studies},

volume = {49},

number = {1},

pages = {10-18},

abstract = {Atelura formicaria belongs to a basal hexapod group, the Zygentoma. Its midgut epithelium is composed of epithelial cells, which are responsible for digestion, secretion, and absorption, and regenerative cells, which form regenerative nests. The midgut epithelium ultrastructure was compared to that described for other zygentoman groups, the Lepismatidae, and the Archaeognatha, a group closely related to the Zygentoma. Among regenerative cells, we distinguished midgut stem cells (resting regenerative cells), which are able to proliferate and differentiate, and differentiating regenerative cells. Just before mitotic division in the cytoplasm of stem cells, many cisterns of endoplasmic reticulum and electrondense granules appear. During mitosis, the electron-dense granules are still present, but are not visible in the resting regenerative cells. A morphological sign of midgut stem cell differentiation is the accumulation of mitochondria just above the nuclei. They gradually assume characteristic features of epithelial cells during elongation toward the midgut lumen. Proliferation and differentiation of regenerative cells are caused by processes of degeneration (apoptosis and necrosis), which intensively occur in the midgut epithelium of A.formicaria.},

note = {18},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-74149092436,

title = {The role of cell death in the midgut epithelium in Filientomon takanawanum (Protura)},

author = { M.M. Rost-Roszkowska and R. Machida and M. Fukui},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-74149092436&doi=10.1016%2fj.tice.2009.06.003&partnerID=40&md5=7be7f40e1e0b319e70308205f38cbf19},

doi = {10.1016/j.tice.2009.06.003},

issn = {00408166},

year  = {2010},

date = {2010-01-01},

journal = {Tissue and Cell},

volume = {42},

number = {1},

pages = {24-31},

publisher = {Elsevier Ltd},

abstract = {Midgut epithelium in Filientomon takanawanum is composed of epithelial cells and single, sporadic regenerative cells. In 80% of analyzed specimens midgut epithelial cells, as fat body and gonads, are infected with rickettsia-like microorganism. In non-infected specimens young and completely differentiated epithelial cells are distinguished among epithelial cells. Characteristic for midgut epithelial cells regionalization in organelles distribution is not observed. Autophagy is the sporadic process, but if the cytoplasm of epithelium cells possesses numerous spherites and sporadic autophagosomes, the apoptosis begins. Necrosis is observed sporadically. In the midgut epithelium cells of about 80% of analyzed specimens rickettsia-like microorganisms are observed. The more rickettsia-like microorganisms occur in the cytoplasm, the more autophagosomes are formed, and the process of apoptosis proceeds intensively. © 2009 Elsevier Ltd. All rights reserved.},

note = {32},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-54349111178,

title = {Degeneration of the midgut epithelium in Epilachna cf. nylanderi (Insecta, Coccinellidae): Apoptosis, autophagy, and necrosis},

author = { M.M. Rost-Roszkowska and I. Poprawa and J. Klag and P. Migula and J. Mesjasz-Przybyłowicz and W.J. Przybyłowicz},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-54349111178&doi=10.1139%2fZ08-096&partnerID=40&md5=a31b6ec1e4c785eac6506fe4bd370a18},

doi = {10.1139/Z08-096},

issn = {00084301},

year  = {2008},

date = {2008-01-01},

journal = {Canadian Journal of Zoology},

volume = {86},

number = {10},

pages = {1179-1188},

abstract = {This study investigates mechanisms of adaptation to metal toxicity peculiar to the midgut epithelium of Epilachna cf. nylanderi (Mulsant; 1850) (Coccinellidae). This species of beetle has currently been identified in only one locality in South Africa and is known to feed on the nickel hyperaccumulator Berkheya coddii Roessl. (Asteraceae), an endemic plant species of the South African ultramafic ecosystem. Our focus involves an analysis of the morphological features of cells forming the midgut epithelium, which is the first organ exposed to toxic levels of metals ingested by the insect. Through the three key processes of apoptosis, necrosis, and autophagy, excess metals are eliminated from the organism and homeostatic conditions are maintained. Apoptosis and necrosis are both known to be involved in the degradation of midgut epithelial cells, while the role of autophagy is mainly implicated in the disintegration of the organelles of cells. This study reports on the participation of these three key degenerative processes in the removal of excess metals based on targeted observations of the insect midgut epithelium by light and electron microscopies. Additionally, the TUNEL reaction was specifically used to detect apoptosis. © 2008 NRC.},

note = {42},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-51549119063,

title = {Degeneration of the midgut epithelium in Allacma fusca L. (Insecta, Collembola, Symphypleona): Apoptosis and necrosis},

author = { M.M. Rost-Roszkowska},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-51549119063&doi=10.2108%2fzsj.25.753&partnerID=40&md5=c9849f2336f1526ab8bd22b4a3e0c5fe},

doi = {10.2108/zsj.25.753},

issn = {02890003},

year  = {2008},

date = {2008-01-01},

journal = {Zoological Science},

volume = {25},

number = {7},

pages = {753-759},

abstract = {Apoptotic and necrotic changes in the midgut epithelium cells of Allacma fusca (Collembola; Symphypleona) are described at the ultrastructural level. The morphological sign indicating the beginning of the apoptotic process in these cells is their shrinkage and the transformation of their mitochondria. The nucleus assumes a lobular shape and finally undergoes fragmentation. The intercellular junctions between an apoptotic cell and adjacent epithelial cells gradually disappear. Apoptotic cells are discharged into the midgut lumen just beneath the peritrophic membrane, where they are initially distributed singly but ultimately form a single layer. No phagocytosis was observed, so no apoptotic bodies are formed. Only young midgut epithelium shows apoptosis; as cells age, necrosis accompanies apoptosis, and necrosis finally completely replaces apoptosis. © 2008 Zoological Society of Japan.},

note = {11},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-42149100666,

title = {Fine structure and differentiation of the midgut epithelium of Allacma fusca (Insecta: Collembola: Symphypleona)},

author = { M.M. Rost-Roszkowska and A. Undrul},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-42149100666&partnerID=40&md5=2e8192a3eb56390f8354902448c9611a},

issn = {10215506},

year  = {2008},

date = {2008-01-01},

journal = {Zoological Studies},

volume = {47},

number = {2},

pages = {200-206},

abstract = {Allacma fusca belongs to a less well known, primitive, wingless insect group. The aim of our study was to describe all changes which accompany midgut epithelium differentiation of adult specimens of A. fusca. The midgut epithelium of A. fusca is composed of columnar cells with an epithelial character. No regenerative cells, which are commonly responsible for midgut epithelium regeneration, were observed. Therefore the growth of the entire epithelium depends on an increase in the dimensions of epithelial cells. Epithelial cells are not able to proliferate, as was earlier suggested, in the 1st larval stage of this species. The characteristic regionalization in the organelle arrangement was observed like in all epithelia responsible for secretion, transport, and excretion. However during the insect's lifespan, distinct differences appear between all epithelial cells. Allacma fusca does not have Malpighian tubules; thus the midgut epithelium is also responsible for excretion. This process is connected with urospherites which accumulate in epithelial cells. Their structure suggests that they might be identified with type A granules described for many Pterygota insects.},

note = {15},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-39049087579,

title = {Ultrastructural changes in the midgut epithelium of Acheta domesticus (Orthoptera: Gryllidae) during degeneration and regeneration},

author = { M.M. Rost-Roszkowska},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-39049087579&doi=10.1603%2f0013-8746%282008%29101%5b151%3aUCITME%5d2.0.CO%3b2&partnerID=40&md5=2b9be27f372e1a74c9f9c9f77d65e03d},

doi = {10.1603/0013-8746(2008)101[151:UCITME]2.0.CO;2},

issn = {00138746},

year  = {2008},

date = {2008-01-01},

journal = {Annals of the Entomological Society of America},

volume = {101},

number = {1},

pages = {151-158},

publisher = {Entomological Society of America},

abstract = {The midgut of Acheta domesticus L. (Orthoptera: Gryllidae) is composed of anterior and posterior paris. Midgut epithelium has columnar digestive cells and regenerative cells, the latter of which form regenerative crypts. Differences at the ultrastructural level between digestive and regenerative cells of the anterior and posterior midgut are described. Processes of degeneration and regeneration are more extensive in the posterior midgut, where entire groups of the digestive cells undergo necrosis, whereas only individual degenerating cells are observed in the anterior midgut. Regenerative cells, which occupy the basal regions of regenerative crypts, proliferate intensively, and they are the stem cells of the midgut epithelium. The cells situated in the apical part of the regenerative crypt assume an epithelial character and differentiate into epithelial cells. Those digestive cells that degenerate separate from the basal lamina and are lost. Regeneration in this species proceeds in a continuous manner. © 2008 Entomological Society of America.},

note = {27},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-37149015692,

title = {Ultrastructural changes in the midgut epithelium of the first larva of Allacma fusca (Insecta, Collembola, Symphypleona)},

author = { M.M. Rost-Roszkowska and I. Poprawa and P. Świątek},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-37149015692&doi=10.1111%2fj.1744-7410.2007.00105.x&partnerID=40&md5=2f8e1358b681cb8ff17e0d3032d20c99},

doi = {10.1111/j.1744-7410.2007.00105.x},

issn = {10778306},

year  = {2007},

date = {2007-01-01},

journal = {Invertebrate Biology},

volume = {126},

number = {4},

pages = {366-372},

abstract = {In the newly hatched larva in Allacma fusca, the midgut epithelium was fully developed and formed by flattened epithelial cells surrounding the yolk mass in the midgut lumen. Immediately after hatching, the first larva began to feed; the migut lumen was filled with the yolk mass and food (mainly algae). Regenerative cells typical of the developing midgut epithelium of many insects were not observed. Initially, midgut cells of the larva were cuboidal but became columnar in shape with distinct regionalization in the distribution of cell organelles. Furthermore, urospherites appeared in the midgut cell cytoplasm, i.e., structures characteristic for the midgut epithelium of insects having no Malpighian tubules. As a result, cells with the capacity for digestion, absorption, and excretion were observed to be completely formed in the first larval stage. © 2007, The American Microscopical Society, Inc.},

note = {8},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-34548454014,

title = {Ultrastructure of alimentary tract formation in embryos of two insect species: Melasoma saliceti and Chrysolina pardalina (Coleoptera, Chrysomelidae)},

author = { M.M. Rost-Roszkowska and A. Kubala and B. Nowak and S. Pilarczyk and J. Klag},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-34548454014&doi=10.1016%2fj.asd.2007.03.002&partnerID=40&md5=04d641a68ef3a63373d1129dac05e1ec},

doi = {10.1016/j.asd.2007.03.002},

issn = {14678039},

year  = {2007},

date = {2007-01-01},

journal = {Arthropod Structure and Development},

volume = {36},

number = {3},

pages = {351-360},

abstract = {Embryogenesis of the alimentary tract in two chrysomelid species (Chrysolina pardalina and Melasoma saliceti) is described. The embryonic development of both species lasts 7 days at room temperature. Stomodaeum and proctodaeum invaginate at the anterior and posterior ends of the germ band. Together with the ectodermal tissue the endoderm cells also enter into the embryo. The anterior and posterior parts of the alimentary tract wedge into the yolk in the form of conical structures. The endodermal cells remain at the yolk surface and start migration over the yolk mass as two lateral bands of cells. The endoderm is always accompanied by mesoderm. On the fifth day of development the endodermal cells together with the mesoderm layer spread over the ventral and dorsal sides of the yolk mass and form the single layered primordium of the midgut epithelium. On the sixth day of development a basal lamina appears between the endoderm and the mesoderm cells and differentiation of both tissues starts. The endodermal epithelium cells change shape from flat to cuboidal and eventually into columnar. Mesoderm cells differentiate into muscle and tracheae. On the 7th day of development stomodaeum and proctodaeum become lined with cuticle and the midgut becomes covered with microvilli. The yolk cells populating the yolk mass do not contribute to midgut formation in the species studied. © 2007 Elsevier Ltd. All rights reserved.},

note = {6},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{2-s2.0-33947416223,

title = {Ultrastructural studies of midgut epithelium formation in Lepisma saccharina L. (Insecta, Zygentoma)},

author = { M.M. Rost-Roszkowska and M. Piłka and R. Szymska and J. Klag},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-33947416223&doi=10.1002%2fjmor.10513&partnerID=40&md5=ba759ea6c5222115d9903a61f63b5b8c},

doi = {10.1002/jmor.10513},

issn = {03622525},

year  = {2007},

date = {2007-01-01},

journal = {Journal of Morphology},

volume = {268},

number = {3},

pages = {224-231},

abstract = {At the end of embryogenesis of Lepisma saccharina L. (Insecta; Zygentoma), when the stomodaeum and proctodaeum are completely formed, the midgut epithelium is replaced by the primary midgut, a yolk mass is surrounded by a cell membrane. Midgut epithelium formation begins in the 1st larval stage. Energids migrate toward the yolk periphery and aggregate just beneath the cell membrane. They are gradually enclosed by cell membrane folds of the primary midgut. Single cells are formed. Succeeding energids join just formed cells. Thus, groups of cells, regenerative cell groups, are formed. Their number gradually increases. The external cells of the regenerative cell groups transform into epithelial cells and their basal regions spread toward the next regenerative cell groups. Epithelial cells of neighboring regenerative cell groups join each other to form the epithelium. At the end of the 2nd larval stage, just before molting, degeneration of newly the formed epithelium begins. Remains of organelles and basal membrane occur between the regenerative cell groups. The new epithelium is formed from the regenerative cell groups, which are now termed stem cells of the midgut epithelium. © 2007 Wiley-Liss, Inc.},

note = {18},

keywords = {},

pubstate = {published},

tppubtype = {article}

}